National Prevalence of Social Isolation and Loneliness in Adults with Chronic Obstructive Pulmonary Disease [0.03%]
慢性阻塞性肺疾病成人患者的全国性社交孤立和孤独患病率调查
Angela O Suen,Anand S Iyer,Irena Cenzer et al.
Angela O Suen et al.
Rationale: Social isolation and loneliness are gaining recognition for their role in health outcomes, yet they have not been defined in people with chronic obstructive pulmonary disease (COPD). Objective: To determine the national prevalenc...
Accuracy of Pulse Oximetry for Long-Term Oxygen Therapy Assessment in Chronic Obstructive Pulmonary Disease [0.03%]
脉氧测定在慢性阻塞性肺病长期氧疗评估中的准确性
Brian Garnet,Rodrigo Diaz-Lankenau,Elie Jean et al.
Brian Garnet et al.
Rationale: Landmark studies of long-term oxygen therapy (LTOT) in patients with chronic obstructive pulmonary disease (COPD) used arterial oxygen pressure (PaO2) to define severe hypoxemia; however, oxygen saturation as measured by pulse ox...
Dynamic Ventilatory Reserve During Incremental Exercise: Reference Values and Clinical Validation in Chronic Obstructive Pulmonary Disease [0.03%]
incremental exercise时的动态通气储备：慢性阻塞性肺疾病患者的参考值和临床验证
Danilo C Berton,Franciele Plachi,Matthew D James et al.
Danilo C Berton et al.
Rationale: Ventilatory demand-capacity imbalance, as inferred based on a low ventilatory reserve, is currently assessed only at peak cardiopulmonary exercise testing (CPET). Peak ventilatory reserve, however, is poorly sensitive to the subm...
Awakening and Breathing Coordination: A Mixed-Methods Analysis of Determinants of Implementation [0.03%]
觉醒与呼吸协调：实施决定因素的混合方法分析
Griffin H Olsen,Perry M Gee,Doug Wolfe et al.
Griffin H Olsen et al.
Rationale: Routine spontaneous awakening and breathing trial coordination (SAT/SBT) improves outcomes for mechanically ventilated patients, but adherence varies. Understanding barriers to and facilitators of consistent daily use of SAT/SBT ...
A Novel Approach to Clinical Change Endpoints: A Win Ratio Analysis of the INCREASE Trial [0.03%]
INCREASE研究的胜率分析：临床替代终点的新方法
Steven D Nathan,Boris Medarov,Lawrence Ho et al.
Steven D Nathan et al.
Sleep Architecture Patterns in Critically Ill Patients and Survivors of Critical Illness: A Retrospective Study [0.03%]
危重患者和重症幸存者的睡眠结构模式：一项回顾性研究
Dimitris Georgopoulos,Eumorfia Kondili,Beth Gerardy et al.
Dimitris Georgopoulos et al.
Rationale: Sleep abnormalities are very frequent in critically ill patients during and after intensive care unit (ICU) stays. Their mechanisms are poorly understood. The odds ratio product (ORP) is a continuous metric (range, 0.0-2.5) of sl...
Drive versus Pressure Contributions to Genioglossus Activity in Obstructive Sleep Apnea [0.03%]
阻塞性睡眠呼吸暂停症的舌骨肌活动的驱动和压力贡献因素分析
Laura K Gell,Daniel Vena,Kevin Grace et al.
Laura K Gell et al.
Rationale: Loss of pharyngeal dilator muscle activity is a key determinant of respiratory events in obstructive sleep apnea (OSA). After the withdrawal of wakefulness stimuli to the genioglossus at sleep onset, mechanoreceptor negative pres...
Obstructive Sleep Apnea Is a Distinct Physiological Endotype in Individuals with Comorbid Insomnia and Sleep Apnea [0.03%]
共病失眠和睡眠呼吸暂停患者的阻塞性睡眠呼吸暂停是不同的生理亚型
Elliot J Brooker,Shane A Landry,Luke D J Thomson et al.
Elliot J Brooker et al.
Rationale: With up to 40% of individuals with either insomnia or obstructive sleep apnea (OSA) demonstrating clinically significant symptoms of the other disorder, the high degree of comorbidity among the two most common sleep disorders sug...
A Randomized Controlled Clinical Trial of Lung Volume Recruitment in Adults with Neuromuscular Disease [0.03%]
神经肌肉疾病成人肺体积招募的随机对照临床试验
Nicole L Sheers,Mark E Howard,Peter D Rochford et al.
Nicole L Sheers et al.
Rationale: Clinical care guidelines advise that lung volume recruitment (LVR) be performed routinely by people with neuromuscular disease (NMD) to maintain lung and chest wall flexibility and slow lung function decline. However, the evidenc...
Randomized Controlled Trial
Annals of the American Thoracic Society. 2023 Oct;20(10):1445-1455. DOI:10.1513/AnnalsATS.202212-1062OC 2023
Eric Gartman,Matthew Jankowich
Eric Gartman