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Clinical Trial Case Reports Meta-Analysis RCT Review Systematic Review
Classical Article Case Reports Clinical Study Clinical Trial Clinical Trial Protocol Comment Comparative Study Editorial Guideline Letter Meta-Analysis Multicenter Study Observational Study Randomized Controlled Trial Review Systematic Review
Alison M DeDent,Harold R Collard,Neeta Thakur Alison M DeDent
Rationale: Living in a disadvantaged neighborhood has been associated with worse survival in people with idiopathic pulmonary fibrosis (IPF), however, prior studies have only examined the impact of neighborhood health on outcomes in IPF as ...
Rachel M Thomson,Michael R Loebinger,Andrew J Burke et al. Rachel M Thomson et al.
Rationale: Inhaled granulocyte-macrophage colony-stimulating factor (GM-CSF) has been proposed as a potential immunomodulatory treatment for nontuberculous mycobacterial (NTM) infection.Objectives: This open-label, noncomparative pilot tria...
Gerard J Criner,Jorge M Mallea,Muhanned Abu-Hijleh et al. Gerard J Criner et al.
Rationale: Follow-up of patients with emphysema treated with endobronchial valves is limited to 3-12 months after treatment in prior reports. To date, no comparative data exist between treatment and control subjects with a longer follow-up....
Snigdha Jain,Aruna Priya,Penelope Pekow et al. Snigdha Jain et al.
Rationale: One quarter of Medicare beneficiaries hospitalized for chronic obstructive pulmonary disease (COPD) die within 1 year. Although overall mortality rates are higher among White patients with COPD, racial and ethnic differences in t...
Christopher N Schmickl,Jeremy E Orr,Scott A Sands et al. Christopher N Schmickl et al.
Rationale: Randomized trials have shown inconsistent cardiovascular benefits from obstructive sleep apnea (OSA) therapy. Intermittent hypoxemia can increase both sympathetic nerve activity and loop gain ("ventilatory instability"), which ma...
John P Donnelly,Sarah M Seelye,Patricia Kipnis et al. John P Donnelly et al.
Rationale: Shorter time-to-antibiotics is lifesaving in sepsis, but programs to hasten antibiotic delivery may increase unnecessary antibiotic use and adverse events. Objectives: We sought to estimate both the benefits and harms of shorteni...
Jeremy T Hua,Lauren M Zell-Baran,Camille M Moore et al. Jeremy T Hua et al.
Rationale: Indigenous populations in the United States face numerous health disparities, but the health of Indigenous workers is less well understood. In a recent surveillance study of active Indigenous coal miners, 3% had coal workers' pne...
Jason M Castaneda,Travis Hee Wai,Laura J Spece et al. Jason M Castaneda et al.
Rationale: Nonbenzodiazepine benzodiazepine receptor agonists (NBZRA, e.g., zolpidem) are frequently used to treat insomnia among patients with chronic obstructive pulmonary disease (COPD). However, multiple observational studies find that ...