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Clinical Trial Case Reports Meta-Analysis RCT Review Systematic Review
Classical Article Case Reports Clinical Study Clinical Trial Clinical Trial Protocol Comment Comparative Study Editorial Guideline Letter Meta-Analysis Multicenter Study Observational Study Randomized Controlled Trial Review Systematic Review
Lakshay Jain,Anil Perumbeti Lakshay Jain
Rationale and objectives: Intrapleural tissue plasminogen activator (tPA) plus deoxyribonuclease (DNase) improves drainage in pleural infection, but the optimal administration sequence is uncertain. We evaluated whether c...
Huijie Yi,Jingjing Guo,Brendan T Keenan et al. Huijie Yi et al.
Objectives: Multiple studies have shown that symptom-based subtypes of obstructive sleep apnea (OSA) exist and are generalizable to clinical and population-based samples of different race/ethnic and regional backgrounds. ...
Tijana Milinic,Amalia S Magaret,Crystal E Brown et al. Tijana Milinic et al.
Rationale: Black and Hispanic people with CF (PwCF) experience worse health outcomes related to pulmonary disease compared to White, non-Hispanic PwCF. Improving outcomes in minoritized PwCF is a crucial need in the CF co...
Paul McNally,Karen Lester,Rachel Cregan et al. Paul McNally et al.
Rationale: Progressive structural lung disease (SLD) is a key hallmark of cystic fibrosis. The CFTR modulator combination Elexacaftor/Tezacaftor/Ivacaftor (ETI) is associated with short term improvements in SLD measured o...
Lindsey L Scheller,Abbey Alkon,Thomas J Hoffmann et al. Lindsey L Scheller et al.
Rationale: Although discharge to home is the goal for many children on new long-term mechanical ventilation via tracheostomy (LTMV-T), families often face barriers to access such as home health nursing. Disparities in dis...
Meagan Deviaene,Victoria Haldane,Jason E Black et al. Meagan Deviaene et al.
Background: Bronchiectasis, a condition defined by radiographic evidence of abnormally widened airways, is increasing in prevalence. Previous studies have demonstrated increased morbidity and health care utilization among...
Rina So,Jiawei Zhang,Marie Bergmann et al. Rina So et al.
Rationale: Long-term exposure to air pollution contributes to chronic respiratory diseases, including asthma and chronic obstructive pulmonary disease (COPD). While the effect of fine particulate matter (PM2.5) and nitrog...