Bacteriophage Infections of Biofilms of Health Care-Associated Pathogens: Klebsiella pneumoniae [0.03%]
医院相关病原菌生物膜的噬菌体感染：肺炎克雷伯氏菌
Ariel J Santiago,Rodney M Donlan
Ariel J Santiago
Members of the family Enterobacteriaceae, such as Klebsiella pneumoniae, are considered both serious and urgent public health threats. Biofilms formed by these health care-associated pathogens can lead to negative and costly health outcomes...
Prokaryotic Organelles: Bacterial Microcompartments in E. coli and Salmonella [0.03%]
原核细胞器：在大肠杆菌和沙门氏菌中的细菌微隔室
Katie L Stewart,Andrew M Stewart,Thomas A Bobik
Katie L Stewart
Bacterial microcompartments (MCPs) are proteinaceous organelles consisting of a metabolic pathway encapsulated within a selectively permeable protein shell. Hundreds of species of bacteria produce MCPs of at least nine different types, and ...
Jonathan N V Martinson,Seth T Walk
Jonathan N V Martinson
Escherichia coli is one of the most well-studied bacterial species, but several significant knowledge gaps remain regarding its ecology and natural history. Specifically, the most important factors influencing its life as a member of the he...
Tânia A T Gomes,Tadasuke Ooka,Rodrigo T Hernandes et al.
Tânia A T Gomes et al.
Escherichia albertii is an emerging enteropathogen of humans and many avian species. This bacterium is a close relative of Escherichia coli and has been frequently misidentified as enteropathogenic or enterohemorrhagic E. coli due to their ...
Matthew R Hemm,Jeremy Weaver,Gisela Storz
Matthew R Hemm
Escherichia coli was one of the first species to have its genome sequenced and remains one of the best-characterized model organisms. Thus, it is perhaps surprising that recent studies have shown that a substantial number of genes have been...
Inhibition of RNA Polymerase by Rifampicin and Rifamycin-Like Molecules [0.03%]
利福平和类似利福霉素的分子对RNA聚合酶的抑制作用
Hamed Mosaei,Nikolay Zenkin
Hamed Mosaei
RNA polymerases (RNAPs) accomplish the first step of gene expression in all living organisms. However, the sequence divergence between bacterial and human RNAPs makes the bacterial RNAP a promising target for antibiotic development. The mos...
Trans-Acting Small RNAs and Their Effects on Gene Expression in Escherichia coli and Salmonella enterica [0.03%]
参与调控的小分子RNA及其对大肠杆菌和沙门氏菌基因表达的影响
Jens Hör,Gianluca Matera,Jörg Vogel et al.
Jens Hör et al.
The last few decades have led to an explosion in our understanding of the major roles that small regulatory RNAs (sRNAs) play in regulatory circuits and the responses to stress in many bacterial species. Much of the foundational work was ca...
Chromosomal Organization and Regulation of Genetic Function in Escherichia coli Integrates the DNA Analog and Digital Information [0.03%]
大肠杆菌染色体的组织与调控整合了DNA模拟和数字信息
Andrew Travers,Georgi Muskhelishvili
Andrew Travers
In this article, we summarize our current understanding of the bacterial genetic regulation brought about by decades of studies using the Escherichia coli model. It became increasingly evident that the cellular genetic regulation system is ...
EnvZ/OmpR Two-Component Signaling: An Archetype System That Can Function Noncanonically [0.03%]
非 kanonisch 功能的 EnvZ/OmpR 二元信号转导系统
Linda J Kenney,Ganesh S Anand
Linda J Kenney
Two-component regulatory systems represent the major paradigm for signal transduction in prokaryotes. The simplest systems are composed of a sensor kinase and a response regulator. The sensor is often a membrane protein that senses a change...
Stewart G Gardner,William R McCleary
Stewart G Gardner
Phosphorus is required for many biological molecules and essential functions, including DNA replication, transcription of RNA, protein translation, posttranslational modifications, and numerous facets of metabolism. In order to maintain the...