Andrei Kuzminov
Andrei Kuzminov
Homologous recombination is the most complex of all recombination events that shape genomes and produce material for evolution. Homologous recombination events are exchanges between DNA molecules in the lengthy regions of shared identity, c...
Agnes Ullmann
Agnes Ullmann
The creation of the "Phage group" by M. Delbrück, S. E. Luria, and A. D. Hershey in 1940 at Cold Spring Harbor played a crucial role in the development of molecular biology. In the 1940s, working with Escherichia coli and its viruses, Luri...
Axel Magalon,Ralf R Mendel
Axel Magalon
The transition element molybdenum (Mo) is of primordial importance for biological systems, because it is required by enzymes catalyzing key reactions in the global carbon, sulfur, and nitrogen metabolism. To gain biological activity, Mo has...
Natassja G Bush,Katherine Evans-Roberts,Anthony Maxwell
Natassja G Bush
DNA topoisomerases are enzymes that control the topology of DNA in all cells. There are two types, I and II, classified according to whether they make transient single- or double-stranded breaks in DNA. Their reactions generally involve the...
The "Cryptic" Escherichia [0.03%]
“隐秘”的大肠杆菌
Seth T Walk
Seth T Walk
In 2009, five monophyletic Escherichia clades were described and referred to as "cryptic" based on the inability to distinguish them from representative E. coli isolates using diagnostic biochemical reactions. Since this original publicatio...
The SOS Regulatory Network [0.03%]
SOS调控网络
Lyle A Simmons,James J Foti,Susan E Cohen et al.
Lyle A Simmons et al.
All organisms possess a diverse set of genetic programs that are used to alter cellular physiology in response to environmental cues. The gram-negative bacterium, Escherichia coli, mounts what is known as the "SOS response" following DNA da...