James B Kaper
James B Kaper
EcoSal Plus (ESP) is the authoritative online review journal that publishes an ever-growing body of expert reviews covering virtually all aspects of Escherichia coli, Salmonella, and other members of the order Enterobacterales and their use...
Transcriptional reprogramming by bacteriophage T4: turning the host transcriptional machinery to the dark side [0.03%]
噬菌体T4转录重编程：将宿主的转录机制引向“黑暗”方面
Deborah M Hinton
Deborah M Hinton
Immediately after infection of Escherichia coli, bacteriophage T4 begins to reprogram the host's transcriptional machinery, first by chemical modification and then by producing factors that alter the specificity of RNA polymerase (RNAP). Th...
Venigalla B Rao
Venigalla B Rao
It has been a 45-year journey studying genome packaging of a single virus, the tailed bacteriophage T4. T4, then and now, remains a powerful model for understanding viruses, particularly tailed phages, the most abundant and widely distribut...
The bacteriophage T4 homologous recombination system: mechanism, applications, conservation, and environmental significance [0.03%]
大肠杆菌T4噬菌体同源重组系统：机制、应用、保守性和环境意义
Scott W Morrical
Scott W Morrical
The homologous recombination (HR) system of bacteriophage T4 plays critical, direct roles in the replication and repair of the phage genome. This review covers the classic, UvsX-dependent HR pathway in T4, focusing on recent findings on the...
The bacteriophage T4 replisome: a model system for understanding DNA replication mechanisms [0.03%]
大肠杆菌T4噬菌体复制酶复合物：理解DNA复制机制的模型系统
Michelle M Spiering,Stephen J Benkovic
Michelle M Spiering
The bacteriophage T4 replisome is a complex molecular machine responsible for DNA replication in the T4 phage. It consists of multiple proteins that work together to ensure efficient and accurate replication of the phage genome. The repliso...
Brian P Anton,Robert Blumenthal,James B Eaglesham et al.
Brian P Anton et al.
Understanding the mechanisms that modulate horizontal genetic exchange in prokaryotes is a key problem in biology. DNA entry is limited by resident host-dependent restriction-modification (RM) systems (HDRM), which are present in most proka...
Jinshil Kim,Bokyung Son
Jinshil Kim
Bacteriophage T4 has provided a model system for understanding post-transcriptional regulation in prokaryotes. This review summarizes several mechanisms of RNA processing and translational control in T4 infection, focusing on the coordinate...
The role of macromolecular crowders in the formation and compaction of the Escherichia coli nucleoid [0.03%]
大分子拥挤物在大肠杆菌核区形成及致密化过程中的作用研究
Jaan Männik,Jaana Männik,Chathuddasie Amarasinghe et al.
Jaan Männik et al.
The chromosomal DNA of Escherichia coli is approximately a thousand times longer than the linear dimensions of the cell it occupies. Nevertheless, it fills only about one-half of the cytosolic volume of the cell. The volume pervaded by the ...
Nicola Holden,Jeri Barak
Nicola Holden
Escherichia coli and non-typhoidal Salmonella enterica are capable of persisting and growing in a wide range of environments. Although best known for their interactions and pathogenic phenotypes in warm-blooded animal hosts, they can be loc...
Viktoria Van Nederveen,Angela R Melton-Celsa
Viktoria Van Nederveen
A cause of diarrhea worldwide, enteroaggregative Escherichia coli (or EAEC) is one of six diarrheagenic E. coli pathotypes. EAEC strains are heterogeneic in terms of virulence factors, adhere strongly to epithelial cells, and produce a stro...