Role of reactive oxygen species and oxidative stress in the pathomechanism of glaucoma [0.03%]
活性氧和氧化应激在青光病发病机制中的作用
Nicholas T H Chan,Ushasree Pattamatta,Andrew White
Nicholas T H Chan
Background: Glaucoma is a major cause of vision impairment and blindness, characterized by damage to retinal ganglion cells (RGC) at the optic nerve head (ONH). The pathomechanism underlying glaucoma is heterogeneous and ...
Visual outcomes for the initial 500 eyes treated with keratorefractive lenticule extraction (KLEx) for myopia and myopic astigmatism at a single-site [0.03%]
首个性圆晶体取出术(KLEx)治疗近视及近视散光的视觉效果分析
Bryce L Palmer,Mina M Sitto,Jonathan C Davis et al.
Bryce L Palmer et al.
Background: Keratorefractive lenticule extraction (KLEx) has become a widely used corneal refractive surgery. Since its approval by the United States Food and Drug Administration (FDA), there are relatively few studies fr...
Reactive oxygen species and oxidative stress in ocular disease: from molecular mechanisms to targeted therapies [0.03%]
眼部疾病的活性氧和氧化应激：从分子机制到靶向治疗
Yara Abukhaled
Yara Abukhaled
Background: Reactive oxygen species and oxidative stress are increasingly recognized as central drivers in the development of major ocular diseases, including cataracts, age-related macular degeneration, glaucoma, and dia...
Ozlem Ozkan,Canan Asli Utine
Ozlem Ozkan
Background: The cornea and ocular surface serve as a vital barrier and the eye's primary refractive medium, requiring precise coordination to maintain transparency, structural integrity, and immune protection. Constantly ...
Scleral lenses and PROSE: indications, complications, and future challenges [0.03%]
角膜接触镜和PROSE：适应证、并发症及未来挑战
Alejandro Rodriguez-Garcia,Julio C Jimenez-Perez,Raul E Ruiz-Lozano et al.
Alejandro Rodriguez-Garcia et al.
Background: Scleral lenses (SLs) and prosthetic replacement of the ocular surface environment (PROSE) are the same device, designed to enhance the optical quality of irregular surfaces or ectatic corneas. They also improv...
Bilateral superior oblique suture extension in pediatric A-pattern esotropia [0.03%]
儿童A型位斜视的双侧上斜肌延长缝合术
Ye Haiyun,Fang Wangyi,Cheng Chi et al.
Ye Haiyun et al.
Background: A-pattern esotropia is defined as an increase of more than 10 prism diopters (PD) divergence in down-gaze than in up-gaze. The long-term outcomes of bilateral superior oblique tendon suture extension (SOSE), a...
Acanthamoeba keratitis: from pathophysiology to prevention, a contemporary clinical perspective [0.03%]
棘阿米巴角膜炎：从病理生理到预防的当代临床视角
Pelin Kiyat,Melis Palamar
Pelin Kiyat
Background: Acanthamoeba keratitis represents a devastating corneal infection caused by free-living protozoan organisms. This condition has evolved from an extraordinarily rare disease to a significant public health conce...
Seher Koksaldi,Omer Karti,Ali Osman Saatci
Seher Koksaldi
Background: Retinal diseases, including neovascular age-related macular degeneration, diabetic retinopathy, and retinal vein occlusion, are leading causes of vision loss worldwide. The introduction of anti-vascular endoth...
Ethical integrity in systematic reviews and meta-analyses: challenges, pitfalls, and best practices in ophthalmology [0.03%]
眼科学系统评价和Meta分析的伦理完整性：挑战、陷阱和最佳实践
Yara Abukhaled,Tharaa M Allawama,Hashem Abu Serhan
Yara Abukhaled
Background: Systematic reviews and meta-analyses (SRMAs) are central to evidence-based ophthalmology, influencing clinical guidelines and treatment decisions. However, the rapid increase in SRMA publications has exposed s...
Janitha Plackal Ayyappan,Zoelfigar Dafalla Mohamed,Gopi Suresh Vankudre et al.
Janitha Plackal Ayyappan et al.
Background: Diabetic retinopathy (DR) is a major microvascular complication of diabetes mellitus (DM) and a leading cause of preventable visual impairment (VI) and blindness worldwide. The rising global prevalence of DM, ...