Designing and conducting systematic reviews and meta-analyses in ophthalmology [0.03%]
眼科系统评价和Meta分析的设计与实施
Abbasali Keshtkar,Mohammadreza Ghasemi
Abbasali Keshtkar
Background: Systematic reviews and meta-analyses represent the highest level of evidence in clinical research, yet their methodological quality in ophthalmology remains inconsistent despite a substantial increase in publi...
Association of the TGF-beta1 polymorphism with primary open-angle glaucoma: a case-control study [0.03%]
转化生长因子-β1基因多态性与原发性开角型青光眼的关联研究
Akbar Derakhshan,Mohammad Javad Zia,Jalil Tavakkol Afshari et al.
Akbar Derakhshan et al.
Background: Primary open-angle glaucoma (POAG) is characterized by increased resistance to aqueous humor outflow. Transforming growth factor beta-1 (TGF-beta1) contributes to this resistance by promoting synthesis and rem...
Systemic and ocular complications related to intravitreal administration of anti-VEGF agents [0.03%]
抗血管内皮生长因子药物玻璃体内注射相关的全身及眼前节并发症
Seher Koksaldi,Mustafa Kayabasi,Omer Karti et al.
Seher Koksaldi et al.
Background: Intravitreal anti-vascular endothelial growth factor (anti-VEGF) injections are the backbone of the treatment of neovascular retinal disorders and among the most frequently performed procedures in ophthalmic p...
Andrzej Grzybowski,Carla Lanca
Andrzej Grzybowski
Background: Myopia is becoming more common in many populations worldwide, particularly in East Asia. It is primarily driven by axial elongation, a structural change associated with increased risks of myopic maculopathy, r...
Topical pyridostigmine for ocular myasthenia gravis: a translational hypothesis [0.03%]
用于眼肌型重症肌无力的滴眼剂吡斯地明:转化医学假说
Edsel B Ing,Kate Lim,Neal M Davies et al.
Edsel B Ing et al.
Background: Myasthenia gravis (MG) is an autoimmune disorder of the neuromuscular junction predominantly mediated by antibodies that target the acetylcholine receptors in the skeletal muscles. Ocular involvement of the le...
Efficacy and safety of pilocarpine as a secretagogue versus artificial tears in the management of dry eye disease [0.03%]
唾液滴定素与人造泪液治疗干眼病的疗效和安全性比较研究
Ehab Mohamed Elsayed Saad,Hazem Elbadry Mohammed Mohammed,Ehab Tharwat et al.
Ehab Mohamed Elsayed Saad et al.
Background: Dry eye disease (DED) is a common multifactorial ocular surface disorder that substantially impairs quality of life and remains among the leading reasons for ophthalmic consultations worldwide. We aimed to com...
Canonical and noncanonical NF-κB signaling in uveal melanoma: mechanisms, microenvironment, and therapeutic modulation [0.03%]
脉络膜黑色素瘤中的经典和非经典NF-κB信号通路:机制、微环境及治疗干预
Sobhan Jalali,Iman Dianat,Sina Baghi Keshtan et al.
Sobhan Jalali et al.
Background: Uveal melanoma (UM) is an aggressive intraocular malignancy with high metastatic potential to the liver and poor prognosis. The nuclear factor kappa B (NF-κB) pathway, comprising the canonical and noncanonica...
Sutureless-dehydrated amniotic membrane (Omnigen®) mounted on contact lens (OmniLenz®) in the treatment of small corneal perforations secondary to exposure keratitis in ICU patients [0.03%]
无缝脱水胎盘膜(Omnigen®)装载于接触镜(OmniLenz®)治疗重症监护病房暴露性角膜炎所致的小角膜穿孔伤
Nancy M Lotfy,Mubarak Alrasheedi,Rola Y Khachaba et al.
Nancy M Lotfy et al.
Background: Exposure keratopathy is a common ocular complication in patients admitted to the intensive care unit (ICU) and may progress from superficial epithelial breakdown to corneal perforation, a vision-threatening em...
Crosslinking of tarsal collagen as a hypothetical therapy for dry eye disease [0.03%]
交联睑结膜胶原蛋白治疗干眼病的假说疗法研究
Alexandra I Manta,Shuko Suzuki,Traian V Chirila
Alexandra I Manta
Background: Dry eye disease (DED) is one of the most prevalent and distressing ocular conditions worldwide; it primarily results from alterations in the natural tear film that covers the ocular surface and is often due to...
Evaluating the predictive value of optical coherence tomography angiography metrics and central corneal thickness among glaucoma suspect patients: a comparative cross-sectional study [0.03%]
基于疑似青光眼患者的光学相干断层扫描血管造影指标和中央角膜厚度的预测价值评估:一项比较性横断面研究
Fathy Mohamed Abo Elftouh Elsalhy,Sarah Abbas Alshamarti,Saif Abbas Alshamarti et al.
Fathy Mohamed Abo Elftouh Elsalhy et al.
Background: Glaucoma suspects (GS) exhibit risk factors such as elevated intraocular pressure (IOP), suspicious optic disc or retinal nerve fiber layer (RNFL) findings, or a positive family history, yet their risk of prog...