Canonical and noncanonical NF-κB signaling in uveal melanoma: mechanisms, microenvironment, and therapeutic modulation [0.03%]
脉络膜黑色素瘤中的经典和非经典NF-κB信号通路：机制、微环境及治疗干预
Sobhan Jalali,Iman Dianat,Sina Baghi Keshtan et al.
Sobhan Jalali et al.
Background: Uveal melanoma (UM) is an aggressive intraocular malignancy with high metastatic potential to the liver and poor prognosis. The nuclear factor kappa B (NF-κB) pathway, comprising the canonical and noncanonica...
Sutureless-dehydrated amniotic membrane (Omnigen®) mounted on contact lens (OmniLenz®) in the treatment of small corneal perforations secondary to exposure keratitis in ICU patients [0.03%]
无缝脱水胎盘膜（Omnigen®）装载于接触镜(OmniLenz®)治疗重症监护病房暴露性角膜炎所致的小角膜穿孔伤
Nancy M Lotfy,Mubarak Alrasheedi,Rola Y Khachaba et al.
Nancy M Lotfy et al.
Background: Exposure keratopathy is a common ocular complication in patients admitted to the intensive care unit (ICU) and may progress from superficial epithelial breakdown to corneal perforation, a vision-threatening em...
Crosslinking of tarsal collagen as a hypothetical therapy for dry eye disease [0.03%]
交联睑结膜胶原蛋白治疗干眼病的假说疗法研究
Alexandra I Manta,Shuko Suzuki,Traian V Chirila
Alexandra I Manta
Background: Dry eye disease (DED) is one of the most prevalent and distressing ocular conditions worldwide; it primarily results from alterations in the natural tear film that covers the ocular surface and is often due to...
Evaluating the predictive value of optical coherence tomography angiography metrics and central corneal thickness among glaucoma suspect patients: a comparative cross-sectional study [0.03%]
基于疑似青光眼患者的光学相干断层扫描血管造影指标和中央角膜厚度的预测价值评估：一项比较性横断面研究
Fathy Mohamed Abo Elftouh Elsalhy,Sarah Abbas Alshamarti,Saif Abbas Alshamarti et al.
Fathy Mohamed Abo Elftouh Elsalhy et al.
Background: Glaucoma suspects (GS) exhibit risk factors such as elevated intraocular pressure (IOP), suspicious optic disc or retinal nerve fiber layer (RNFL) findings, or a positive family history, yet their risk of prog...
Role of reactive oxygen species and oxidative stress in the pathomechanism of glaucoma [0.03%]
活性氧和氧化应激在青光病发病机制中的作用
Nicholas T H Chan,Ushasree Pattamatta,Andrew White
Nicholas T H Chan
Background: Glaucoma is a major cause of vision impairment and blindness, characterized by damage to retinal ganglion cells (RGC) at the optic nerve head (ONH). The pathomechanism underlying glaucoma is heterogeneous and ...
Visual outcomes for the initial 500 eyes treated with keratorefractive lenticule extraction (KLEx) for myopia and myopic astigmatism at a single-site [0.03%]
首个性圆晶体取出术(KLEx)治疗近视及近视散光的视觉效果分析
Bryce L Palmer,Mina M Sitto,Jonathan C Davis et al.
Bryce L Palmer et al.
Background: Keratorefractive lenticule extraction (KLEx) has become a widely used corneal refractive surgery. Since its approval by the United States Food and Drug Administration (FDA), there are relatively few studies fr...
Reactive oxygen species and oxidative stress in ocular disease: from molecular mechanisms to targeted therapies [0.03%]
眼部疾病的活性氧和氧化应激：从分子机制到靶向治疗
Yara Abukhaled
Yara Abukhaled
Background: Reactive oxygen species and oxidative stress are increasingly recognized as central drivers in the development of major ocular diseases, including cataracts, age-related macular degeneration, glaucoma, and dia...
Ozlem Ozkan,Canan Asli Utine
Ozlem Ozkan
Background: The cornea and ocular surface serve as a vital barrier and the eye's primary refractive medium, requiring precise coordination to maintain transparency, structural integrity, and immune protection. Constantly ...
Scleral lenses and PROSE: indications, complications, and future challenges [0.03%]
角膜接触镜和PROSE：适应证、并发症及未来挑战
Alejandro Rodriguez-Garcia,Julio C Jimenez-Perez,Raul E Ruiz-Lozano et al.
Alejandro Rodriguez-Garcia et al.
Background: Scleral lenses (SLs) and prosthetic replacement of the ocular surface environment (PROSE) are the same device, designed to enhance the optical quality of irregular surfaces or ectatic corneas. They also improv...
Bilateral superior oblique suture extension in pediatric A-pattern esotropia [0.03%]
儿童A型位斜视的双侧上斜肌延长缝合术
Ye Haiyun,Fang Wangyi,Cheng Chi et al.
Ye Haiyun et al.
Background: A-pattern esotropia is defined as an increase of more than 10 prism diopters (PD) divergence in down-gaze than in up-gaze. The long-term outcomes of bilateral superior oblique tendon suture extension (SOSE), a...