Association of the rs2814778 variant in the ACKR1 gene, responsible for the Duffy erythrocyte antigen "null" phenotype, with COVID-19 severity in Southern Brazil [0.03%]
南巴西人中负责杜菲红细胞抗原“零”表型的ACKR1基因rs2814778多态性与COVID-19严重程度的关系研究
Kelly Silvério Góis,Matheus Braga,Victor Hugo de Souza et al.
Kelly Silvério Góis et al.
Objective: This study aimed to analyze the possible association between rs2814778, rs12075 ( ACKR1 gene), and rs4073 ( CXCL8 gene) single nucleotide variants and COVID-19 severity. ...
Relationship between physical disability and satisfaction with medical care and health facility infrastructure in Peru [0.03%]
秘鲁身体残疾与医疗护理和卫生设施基础设施满意度之间的关系
Teodoro Gaspar-Roman,J Jhonnel Alarco
Teodoro Gaspar-Roman
Objective: To analyze the association of physical disability with medical care and health center infrastructure satisfaction among users of medical offices in Peru in 2016. ...
Characterization of a novel MSH2 variant in Lynch syndrome: clinical data and complementary bioinformatics assessment [0.03%]
Lynch综合征中新型MSH2变异的特征描述：临床数据和互补生物信息学评估
Anisse Marques Chami,Thalia Rodrigues de Souza Zózimo,Carolina Guimarães Ramos Matosinho et al.
Anisse Marques Chami et al.
Objective: To describe the clinical characteristics and perform a multi-step bioinformatics evaluation of the pathogenicity of NM_000251.3(MSH2):c.1894_1898del (p.Ile633Lysfs*9), an MSH2 germline variant detected in a fam...
Off-label use of thalidomide in children with Crohn's disease and inflammatory bowel diseases [0.03%]
沙利度胺用于克罗恩病及炎症性肠病患儿的超适应症用药研究
Laura Beatriz Fonseca,Paula Lana de Miranda Drummond,Cristine de Araújo Silva et al.
Laura Beatriz Fonseca et al.
Thalidomide exerts immunomodulatory properties that may be used to treat various conditions. Although its effectiveness in treating Crohn's disease in pediatric patients has been reported, its safety for off-label use is not well establishe...
Hypopituitarism and Rathke's cleft cyst in 48,XXYY Syndrome: new insights into sex chromosome aneuploidies [0.03%]
48,XXYY综合征中的垂体功能减退和拉克氏裂囊肿：性染色体非整倍体的新见解
Rafael Loch Batista,Marilena Nakaguma,Leonardo Andrade Gontijo Tavares et al.
Rafael Loch Batista et al.
The 48,XXYY syndrome is a rare sex chromosome aneuploidy associated with diverse physical, developmental, and endocrine abnormalities. This case report highlights a 15-year-old male with 48,XXYY syndrome presenting with hypopituitarism and ...
Intra- and inter-observer reliabilities of cervical sagittal radiographic measurements among evaluators with different levels of training [0.03%]
不同培训水平的评估者颈椎侧位X线测量的组内和组间可靠性研究
Guilherme Pianowski Pajanoti,Gustavo Henrique de Melo Ultchak,Jose Otavio Donadeli Tome et al.
Guilherme Pianowski Pajanoti et al.
Objective: To assess the intra- and inter-observer reliabilities of cervical sagittal radiographic measurements performed by evaluators with varying levels of clinical experience. ...
Effect of simplified exercise program on quality of life, biomarkers, pain and muscle strength of individuals with knee osteoarthritis [0.03%]
简易运动方案对膝骨关节炎患者生活质量、生物标志物、疼痛及肌肉力量的影响研究
Rosana Ravagnani Campedelli,Mariana Rosada de Souza Jardim,Eliane Antonioli et al.
Rosana Ravagnani Campedelli et al.
Objective: To evaluate a simplified exercise program for patients with knee osteoarthritis in terms of pain, functionality, muscle strength, and quality of life. The correlation of serum levels of molecules and cytokines ...
Telerehabilitation with breathing exercises as a strategy to improve functional capacity of patients with chronic obstructive pulmonary disease: randomized clinical trial [0.03%]
远程康复训练中呼吸锻炼改善慢性阻塞性肺病患者功能能力的作用：随机临床试验
Karine Franciele Toldo de Toledo,Sônia Maria Marques Gomes Bertolini,Sônia Trannin de Mello et al.
Karine Franciele Toldo de Toledo et al.
Objective: This study aimed to analyze the effects of two proposed telerehabilitation interventions on the functional capacity of patients with chronic obstructive pulmonary disease. ...
Randomized Controlled Trial
Einstein (Sao Paulo, Brazil). 2025 Dec 1:23:eAO1182. DOI:10.31744/einstein_journal/2025AO1182 2025
Unraveling atherosclerosis through single-cell RNA sequencing: insights into cellular heterogeneity and disease mechanisms [0.03%]
通过单细胞RNA测序解开动脉粥样硬化：探讨细胞异质性和疾病机制的见解
Carlos Vicente Serrano Jr,Matheus Laterza Ribeiro,Luciana Dornfeld Bichuette et al.
Carlos Vicente Serrano Jr et al.
Atherosclerosis remains the leading cause of mortality worldwide. The characterization of atherosclerotic lesions reveals that they represent a chronic and progressive inflammatory condition affecting the arterial wall. Despite extensive in...
Pulmonary nodules near fissures in hepatocellular carcinoma: assessing their clinical significance [0.03%]
肝细胞癌患者肺裂附近结节的临床意义评估
Leonardo Chaves Machado,Gilberto Szarf,Gustavo Borges da Silva Teles et al.
Leonardo Chaves Machado et al.
Objective: To evaluate whether pulmonary nodules adjacent to fissures, particularly perifissural nodules detected on chest computed tomography in patients with hepatocellular carcinoma, can be reliably classified as benig...