Combined tenofovir, lamivudine, and dolutegravir treatment increases leptin and FABP4 expression in human subcutaneous adipose tissue [0.03%]
含有替诺福韦、拉米夫定和多替拉韦的联合治疗可增加人体皮下脂肪组织瘦素和FABP4表达
Luiza Wolf Zanardo,Larissa Dos Santos Izabel,Letícia Miho Hamada et al.
Luiza Wolf Zanardo et al.
Introduction: Several antiretroviral regimens reportedly affect adipose tissue function. While earlier antiretroviral combinations were associated with lipodystrophy, more recent regimens, particularly those containing do...
Effect of respiratory muscle training on functional capacity related to the quality of life of patients undergoing coronary artery bypass grafting with cardiopulmonary bypass: randomized clinical trial [0.03%]
冠脉旁路移植术后呼吸肌训练改善心肺功能的随机对照试验研究
Mary Silva da Cruz Neves Ribeiro,Fabiana Della Via,Antônio Luís Eiras Falcão et al.
Mary Silva da Cruz Neves Ribeiro et al.
Objective: To evaluate the effects of inspiratory muscle training using POWERbreathe® in patients undergoing myocardial revascularization with extracorporeal circulation, focusing on respiratory and peripheral muscle str...
Randomized Controlled Trial
Einstein (Sao Paulo, Brazil). 2026 Feb 16:24:eAO1720. DOI:10.31744/einstein_journal/2026AO1720 2026
A tertiary care study on the effectiveness of moderate weight loss on heart rate variability frequency-domain components in obese patients at high cardiovascular risk [0.03%]
一项针对心血管疾病高危肥胖患者的三级护理研究：中度减肥对心率变异性频率领域成分的有效性
Priscila Moreira,Cristiane Kovacs Amaral,Dalmo Antônio Ribeiro Moreira et al.
Priscila Moreira et al.
Objective: Cardiovascular diseases remain the leading cause of mortality, and obesity is a significant risk factor. This study aimed to investigate the impact of a structured nutritional intervention on weight loss, heart...
Performance of the Artificial Intelligence large language models ChatGPT 3.5, Gemini (Google Bard), ChatGPT 4.0, and Gemini 2.5 flash in surgical subspecialty questions of Brazilian medical residency exams [0.03%]
Maria Clara Pimenta de Figueiredo,Victor Hugo Alves Diniz,Ana Clara de Campos Granado et al.
Maria Clara Pimenta de Figueiredo et al.
Objective: Given the rapid advancement of Artificial Intelligence and its significant impact on medical education, particularly with the development of large language models, such as ChatGPT and Gemini, ChatBots have show...
SARS-CoV-2 infection and profound hearing loss: much more than a coincidence [0.03%]
新冠肺炎感染与重度听力损失：不仅仅是巧合
Pedro Luiz Mangabeira Albernaz,Sady Selaimen da Costa,Vinícius Oliveira Nitz
Pedro Luiz Mangabeira Albernaz
Objective: To describe a series of cases in which severe acute respiratory (SARS-CoV-2) infection was associated with profound sensorineural hearing loss. Our data provides extensive evidence that COVID-19 infections can ...
Kevin Rafael De Paula Morales,André Vaz,Rafaela Vieira Franklin et al.
Kevin Rafael De Paula Morales et al.
Iridoschisis associated with cataract: a systematic review of case reports [0.03%]
与白内障相关的虹膜分裂症：病例报告的系统性回顾
Dillan Cunha Amaral,Márcio Penha Morterá Rodrigues,Guilherme Nunes Marques et al.
Dillan Cunha Amaral et al.
Background: Iridoschisis is a rare, bilateral condition of unknown etiology, often associated with trauma or surgery, in which the iris stroma splits into layers. It is usually associated with glaucoma and cataract. Facec...
Scientific breakthroughs in the COVID-19 era: embracing Ernst Mayr towards an epistemic renewal of Medicine [0.03%]
新冠肺炎时代下的医学科学突破及知识革新：兼论 Ernst Mayr 的科学史贡献
Bruno Gualano,Marcus Sacrini Ayres Ferraz,Anderson Luis Nakano
Bruno Gualano
The present study examines the development of medical science during the COVID-19 pandemic in light of Ernst Mayr's critique of Thomas Kuhn's philosophy of scientific revolutions. Kuhn's model, which emphasizes paradigm shifts and disruptiv...
The new fitness world: commodifying well-being in the neoliberal era [0.03%]
neoliberal时代下的健身新世界：健康福祉的商品化
Bruno Gualano,Hamilton Roschel,Antonio Valverde
Bruno Gualano
This paper examines the fitness industry as a by-product of neoliberal ideology, using "The New Way of the World: On Neoliberal Society" as a conceptual framework. Neoliberalism, as articulated by Dardot and Laval, extends beyond economic p...
The ontology of mental health disorders: embracing the diathesis-stress model [0.03%]
精神障碍的本体论：接受易感-压力模型
André Connor de Méo Luiz,Myenne Mieko Ayres Tsutsumi
André Connor de Méo Luiz
■ This paper proposes a contextual and non-reductionist ontology of mental health disorders. ■ It reframes the diathesis-stress model through radical behaviorism and functional contextualism. ■ It emphasizes dynamic interactions between ...