Molecular and pharmacological aspects of piperine as a potential molecule for disease prevention and management: evidence from clinical trials [0.03%]
临床试验中 pepparine 作为潜在的疾病预防和治疗分子的分子和药理学方面证据
Amit Kumar Tripathi,Anup Kumar Ray,Sunil Kumar Mishra
Amit Kumar Tripathi
Background: Piperine is a type of amide alkaloid that exhibits pleiotropic properties like antioxidant, anticancer, anti-inflammatory, antihypertensive, hepatoprotective, neuroprotective and enhancing bioavailability and ...
Pathophysiological effects of Tamiflu on liver and kidneys of male rats [0.03%]
达菲对雄性大鼠肝脏和肾脏病理生理学影响的研究
Wafaa H Abdel-Ghaffar,Eman A Abdelghffar
Wafaa H Abdel-Ghaffar
Background: Tamiflu/oseltamivir phosphate (OP), an anti-influenza drug, has a highly doubted safety especially after many cases of abnormal behaviour and deaths reported after being used. Such controversy was also locally...
Hydrogel based tissue engineering and its future applications in personalized disease modeling and regenerative therapy [0.03%]
基于水凝胶的组织工程及其在个性化疾病建模和再生治疗中的未来应用
Shikha Chaudhary,Eliza Chakraborty
Shikha Chaudhary
Background: Evolution in the in vitro cell culture from conventional 2D to 3D technique has been a significant accomplishment. The 3D culture models have provided a close and better insight into the physiological study of...
Clinical, laboratory, and radiological characteristics of COVID-19-infected children admitted to pediatric intensive care unit: a single-center experience [0.03%]
儿童新冠重症患者的临床、实验室和影像学特征：单中心经验研究
Heba Mostafa Ahmed,Rehab Muhammad Abd El Kareem,Faten Mohamed Ali et al.
Heba Mostafa Ahmed et al.
Background: During the second wave of COVID-19, there is an increasing incidence of reported cases in children compared to the early wave. Data on the clinical and laboratory characteristics of COVID-19 in children are ev...
Corticosteroids for treatment of COVID-19: effect, evidence, expectation and extent [0.03%]
COVID-19皮质类固醇治疗：效果、证据、期望和范围
Vijay K Patel,Ekta Shirbhate,Preeti Patel et al.
Vijay K Patel et al.
Background: The World Health Organization (WHO) announced the COVID-19 occurrence as a global pandemic in March 2020. The treatment of SARS-CoV-2 patients is based on the experience gained from SARS-CoV and MERS-CoV infec...
Vitamins and other immune-supportive elements as cofactors for passing the COVID-19 pandemic [0.03%]
作为应对COVID-19大流行的协同因素的维生素和其他免疫辅助元素
Haitham Saeed,Hasnaa Osama,Mona A Abdelrahman et al.
Haitham Saeed et al.
Background: Coronavirus disease 2019 (COVID-19) is a viral disease that causes a respiratory disorder, started in December of 2019 in China. Several vitamins and trace elements could help in enhancing host immunity produc...
Search for RNA aptamers against non-structural protein of SARS-CoV-2: Design using molecular dynamics approach [0.03%]
针对SARS-CoV-2非结构蛋白的RNA适体筛选：使用分子动力学方法设计
Ram Kothandan,Pavithra Uthayasooriyan,Sivaranjani Vairamani
Ram Kothandan
Background: Recent outbreak of deadly Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) urges the scientist to identify the potential vaccine or drug to control the disease. SARS-CoV-2 with its single stranded ...
Evolution of RNA viruses from SARS to SARS-CoV-2 and diagnostic techniques for COVID-19: a review [0.03%]
从SARS到SARS-CoV-2的RNA病毒演变及COVID-19的诊断技术：综述
Johra Khan,Lubna Ibrahim Al Asoom,Maryam Khan et al.
Johra Khan et al.
Background: From the start of the twenty-first century up to the year 2021, RNA viruses are the main causative agents of the majority of the disease outbreaks the world has confronted. Recently published reviews on SARS-C...
Phage therapy as a revolutionary medicine against Gram-positive bacterial infections [0.03%]
噬菌体疗法作为治疗革兰氏阳性细菌感染的革命性药物
Archana Loganathan,Prasanth Manohar,Kandasamy Eniyan et al.
Archana Loganathan et al.
Background: Antibiotic resistance among pathogenic bacteria has created a global emergency, prompting the hunt for an alternative cure. Bacteriophages were discovered over a century ago and have proven to be a successful ...
Interaction of SARS-CoV-2 spike protein with angiotensin converting enzyme inhibitors and selected compounds from the chemical entities of biological interest [0.03%]
血管紧张素转换酶抑制剂与生物兴趣化学实体中选定化合物和SARS-CoV-2刺突蛋白的相互作用
Suleiman Aminu,Mohammed Auwal Ibrahim,Abdullahi Balarabe Sallau
Suleiman Aminu
Background: Recent COVID-19 outbreak has prompted the search of novel therapeutic agents to treat the disease. The initial step of the infection involves the binding of the virus through the viral spike protein with the h...