Potential Roles of Exosomal lncRNAs in the Intestinal Mucosal Immune Barrier [0.03%]
外泌体长链非编码RNA在肠道黏膜免疫屏障中的潜在作用
Shanshan Chen,Ruonan He,Beihui He et al.
Shanshan Chen et al.
The intestinal mucosal immune barrier protects the host from the invasion of foreign pathogenic microorganisms. Immune cells and cytokines in the intestinal mucosa maintain local and systemic homeostasis by participating in natural and adap...
Diabetic Bone Marrow Cell Injection Accelerated Acute Pancreatitis Progression [0.03%]
糖尿病骨髓细胞注射加速急性胰腺炎进展
Xiao-Min Luo,Cen Yan,Yue-Jie Zhang et al.
Xiao-Min Luo et al.
Acute pancreatitis (AP) is one of the leading causes of hospital admission, 20% of which could progress to the severe type with extensive acinar cell necrosis. Clinical studies have reported that diabetes is an independent risk factor of th...
Miao Wu,Jiawei Bai,Chengtai Ma et al.
Miao Wu et al.
Tumor immunotherapy is the fourth therapy after surgery, chemotherapy, and radiotherapy. It has made great breakthroughs in the treatment of some epithelial tumors and hematological tumors. However, its adverse reactions are common or even ...
Propofol Suppresses Microglia Inflammation by Targeting TGM2/NF- κ B Signaling [0.03%]
异丙酚通过靶向TGM2/NF-κB信号抑制小胶质细胞炎症反应
Yuanyuan Hou,Xi Xiao,Wei Yu et al.
Yuanyuan Hou et al.
Background: Propofol is a known intravenous hypnotic drug used for induction and maintenance of sedation and general anesthesia. Emerging studies also reveal a neuroprotective effect of propofol in diverse diseases of neu...
METTL3 Intensifies the Progress of Oral Squamous Cell Carcinoma via Modulating the m6A Amount of PRMT5 and PD-L1 [0.03%]
METTL3通过调节PRMT5和PD-L1的m6A含量促进口腔鳞状细胞癌的发展
Yilong Ai,Shiwei Liu,Hailing Luo et al.
Yilong Ai et al.
N6-Methyladenosine (m6A) modification is one of the commonest chemical modifications in eukaryotic mRNAs, which has essential effects on mRNA translation, splicing, and stability. Currently, there is a rising concern on the regulatory role ...
Epitope-Based Immunoinformatic Approach on Heat Shock 70 kDa Protein Complex of Cryptococcus neoformans var. grubii [0.03%]
基于抗原表位的新型免疫信息学方法在新生隐球菌热休克蛋白70中的应用研究
Reham M Elhassan,Nagla M Alsony,Khadeejah M Othman et al.
Reham M Elhassan et al.
Introduction: Cryptococcosis is a ubiquitous opportunistic fungal disease caused by Cryptococcus neoformans var. grubii. It has high global morbidity and mortality among HIV patients and non-HIV carriers with 99% and 95%,...
Systemic Proteomic Analysis Reveals Distinct Exosomal Protein Profiles in Rheumatoid Arthritis [0.03%]
系统蛋白质组学分析揭示类风湿关节炎的特异性外泌体蛋白谱型
Qiu Qin,Ronghua Song,Peng Du et al.
Qiu Qin et al.
Objective: Rheumatoid arthritis (RA) is a complex disease with unknown pathogenesis. In recent years, fewer have paid attention to the broad spectrum of systemic markers of RA. The aim of this study was to identify exosom...
Observational Study
Journal of immunology research. 2021 Aug 18:2021:9421720. DOI:10.1155/2021/9421720 2021
The Role and Function of Regulatory T Cells in Toxoplasma gondii-Induced Adverse Pregnancy Outcomes [0.03%]
调节性T细胞在弓形虫诱导的不良妊娠结局中的作用及机制研究进展
Xuyang Gao,Yue Zhong,Yifan Liu et al.
Xuyang Gao et al.
Infection with Toxoplasma gondii (T. gondii) during the pregnant period and its potentially miserable outcomes for the fetus, newborn, and even adult offspring continuously occur worldwide. People acquire infection through the consumption o...
Immune Characters and Plasticity of the Sentinel Lymph Node in Colorectal Cancer Patients [0.03%]
结直肠癌患者的免疫特征和哨兵淋巴结的可塑性
Xiaoyun Li,Jingling Tang,Hang Du et al.
Xiaoyun Li et al.
Purpose: This study is aimed at immunologically characterizing sentinel lymph nodes (SNs) in colorectal cancer (CRC) patients and identifying changes in immunological phenotype and function of SNs isolated from the tumor ...
Observational Study
Journal of immunology research. 2021 Aug 18:2021:5516399. DOI:10.1155/2021/5516399 2021
Probiotics Alleviated Nonalcoholic Fatty Liver Disease in High-Fat Diet-Fed Rats via Gut Microbiota/FXR/FGF15 Signaling Pathway [0.03%]
益生菌通过肠道微生物群/FXR/FGF15信号通路缓解高脂饮食喂养大鼠的非酒精性脂肪肝病
Minmin Luo,Junbin Yan,Liyan Wu et al.
Minmin Luo et al.
Gut microbiota (GM) dysbiosis and bile acid (BA) metabolism disorder play an important role in the pathogenesis of nonalcoholic fatty liver disease (NAFLD). Probiotics had a beneficial effect on NAFLD, but further study is needed to explore...