Development and Validation of a TNF Family-Based Signature for Predicting Prognosis, Tumor Immune Characteristics, and Immunotherapy Response in Colorectal Cancer Patients [0.03%]
基于TNF家族的特征开发与验证以预测结肠直肠癌患者的预后，肿瘤免疫特性和免疫治疗反应
Zheng Xiao,Kechao Nie,Tong Han et al.
Zheng Xiao et al.
In this study, a comprehensive analysis of TNF family members in colorectal cancer (CRC) was conducted and a TNF family-based signature (TFS) was generated to predict prognosis and immunotherapy response. Using the expression data of 516 CR...
Combination of AAV-CCL19 and GPC3 CAR-T Cells in the Treatment of Hepatocellular Carcinoma [0.03%]
AAV-CCL19与GPC3 CAR-T细胞联合治疗肝癌中的应用
Min Meng,Yi-Chen Wu
Min Meng
Background: Chimeric antigen receptor-modified T cell (CAR-T) therapy has great potential for treating malignant tumors, especially hematological malignancies. However, the therapeutic effect of solid tumors is limited. O...
Tumor Biomarker In-Solution Quantification, Standard Production, and Multiplex Detection [0.03%]
肿瘤生物标志物的溶液定量分析，标准品生产及多指标检测
Nicole C Japp,Joshua J Souchek,Aaron R Sasson et al.
Nicole C Japp et al.
The diagnosis and monitoring of cancer have been facilitated by discovering tumor "biomarkers" and methods to detect their presence. Yet, for certain cancers, we still lack sensitive and specific biomarkers or the means to quantify subtle c...
Circular RNA FOXP1 Induced by ZNF263 Upregulates U2AF2 Expression to Accelerate Renal Cell Carcinoma Tumorigenesis and Warburg Effect through Sponging miR-423-5p [0.03%]
ZNF263诱导的环状RNA FOXP1通过吸附miR-423-5p上调U2AF2表达加速肾细胞癌肿瘤发生和战争效应
Li Fang,Ting Ye,Yanmei An
Li Fang
Renal cell carcinoma (RCC), as one of the most common malignant tumors in the urinary system, is featured with high morbidity and mortality. Although the improvement of clinical intervention, such as surgery technology, chemotherapy, and ra...
Blocking the Hepatic Branch of the Vagus Aggravates Hepatic Ischemia-Reperfusion Injury via Inhibiting the Expression of IL-22 in the Liver [0.03%]
阻断肝支迷走神经通过抑制肝脏IL-22的表达加重肝缺血再灌注损伤
Heng Zhou,Juling Xu,Sanxiong Huang et al.
Heng Zhou et al.
Liver ischemia-reperfusion injury (IRI) is an inevitable process during liver transplantation, hemorrhagic shock, resection, and other liver surgeries. It is an important cause of postoperative liver dysfunction and increased medical costs....
Angiotensin II-Treated Cardiac Myocytes Regulate M1 Macrophage Polarization via Transferring Exosomal PVT1 [0.03%]
经血管紧张素II处理的心肌细胞通过转移exoPVT1调节M1巨噬细胞的极化
Feng Cao,Zhe Li,Wenmao Ding et al.
Feng Cao et al.
Atrial fibrillation (AF) seriously reduces the health and life quality of patients. It is necessary to explore the pathogenesis of AF and provide a new target for the treatment. Here, exosomes were identified using transmission electron mic...
Identification of Immune-Related Risk Signatures for the Prognostic Prediction in Oral Squamous Cell Carcinoma [0.03%]
鉴定口腔鳞状细胞癌预后预测的免疫相关风险标志物
Chen Zou,Dahong Huang,Haigang Wei et al.
Chen Zou et al.
Background: Oral squamous cell carcinoma (OSCC) is the most common type of oral cancer, which remains a major cause of morbidity and mortality in patients with head and neck cancers. However, the critical immune-related s...
Kangli Qiu,Kai Li,Tianshu Zeng et al.
Kangli Qiu et al.
Objective: Hashimoto's thyroiditis, also known as chronic lymphocytic thyroiditis, is a common autoimmune thyroiditis, which mostly occurs in young and middle-aged women. It can be manifested as hyperthyroidism in the ear...
A Perspective on Withania somnifera Modulating Antitumor Immunity in Targeting Prostate Cancer [0.03%]
Withania somnifera调控抗肿瘤免疫在前列腺癌靶向治疗中的作用展望
Seema Dubey,Manohar Singh,Ariel Nelson et al.
Seema Dubey et al.
Medicinal plants serve as a lead source of bioactive compounds and have been an integral part of day-to-day life in treating various disease conditions since ancient times. Withaferin A (WFA), a bioactive ingredient of Withania somnifera, h...
Correlation between Hyperalgesia and Upregulation of TNF- α and IL-1 β in Aqueous Humor and Blood in Second Eye Phacoemulsification: Clinical and Experimental Investigation [0.03%]
临床及实验研究飞秒激光白内障手术第二眼时疼痛加剧与房水和血液中TNF-α、IL-1β上调之间的关系
Ruibo Yang,Chang Liu,Di Yu et al.
Ruibo Yang et al.
The aim of this study was to explore the correlation between intraoperative hyperalgesia of the second eye and the dynamic changes of tumor necrosis factor (TNF)-α and interleukin (IL)-1β levels in aqueous humor (AH) of the second eye and...