Correlation Analysis between Gut Microbiota and Metabolites in Children with Systemic Lupus Erythematosus [0.03%]
儿童系统性红斑狼疮肠道微生物与代谢物相关性分析
Min Wen,Taohua Liu,Mingyi Zhao et al.
Min Wen et al.
Systemic lupus erythematosus (SLE) is an autoimmune-mediated diffuse connective tissue disease characterized by immune inflammation with an unclear aetiology and pathogenesis. This work profiled the intestinal flora and faecal metabolome of...
Anti-Inflammatory and Healing Activity of the Hydroalcoholic Fruit Extract of Solanum diploconos (Mart.) Bohs [0.03%]
Solanum diploconos (Mart.) Bohs果实 hydroalcoholic 提取物的抗炎和促愈合作用
Larissa Benvenutti,Roberta Nunes,Ivonilce Venturi et al.
Larissa Benvenutti et al.
Background: Solanum diploconos (Mart.) Bohs is a native Brazilian plant belonging to the Solanaceae family, popularly known as "tomatinho do mato" and poorly investigated. Herein, we presented for the first time evidence ...
Xin Xia,Jun Yang,Shengjun Wang
Xin Xia
Follicular regulatory T (Tfr) cells are the regulatory T cell subset mainly localized in the germinal center (GC), acting as modulators of GC responses. They can disrupt Tfh cell- and B cell-linked recognition, induce Tfh apoptosis, and sup...
miR-100 Suppresses the Proliferation, Invasion, and Migration of Hepatocellular Carcinoma Cells via Targeting CXCR7 [0.03%]
miR-100通过靶向CXCR7抑制肝癌细胞的增殖、侵袭和迁移
Yiman Ge,Jia Shu,Gang Shi et al.
Yiman Ge et al.
This study is to elucidate the functions of miR-100 in hepatocellular carcinoma progression and to explore the underlying mechanisms. Expression levels of miR-100 in normal-cancer hepatocellular carcinoma tissues were measured using quantit...
Observational Study
Journal of immunology research. 2021 Jul 17:2021:9920786. DOI:10.1155/2021/9920786 2021
Predictive Significance of the Prognostic Nutritional Index (PNI) in Patients with Severe COVID-19 [0.03%]
预后营养指数(PNI)对重症新型冠状病毒肺炎患者的预测意义
Wei Wei,Xingyue Wu,Chaoyuan Jin et al.
Wei Wei et al.
Background: The prognostic nutritional index (PNI) has been reported to significantly correlate with poor survival and postoperative complications in patients with various diseases, but its relationship with mortality in ...
Multicenter Study
Journal of immunology research. 2021 Jul 9:2021:9917302. DOI:10.1155/2021/9917302 2021
Crosstalk between Tumor-Infiltrating Immune Cells and Cancer-Associated Fibroblasts in Tumor Growth and Immunosuppression of Breast Cancer [0.03%]
肿瘤浸润免疫细胞与癌症相关成纤维细胞在乳腺癌生长和免疫抑制中的相互作用
Jarupa Soongsathitanon,Pranisa Jamjuntra,Nuttavut Sumransub et al.
Jarupa Soongsathitanon et al.
Signals from the tumor microenvironment (TME) have a profound influence on the maintenance and progression of cancers. Chronic inflammation and the infiltration of immune cells in breast cancer (BC) have been strongly associated with early ...
RNA-seq and In Vitro Experiments Reveal the Protective Effect of Curcumin against 5-Fluorouracil-Induced Intestinal Mucositis via IL-6/STAT3 Signaling Pathway [0.03%]
RNA测序及体外实验揭示姜黄素通过IL-6/STAT3信号通路对抗氟尿嘧啶所致肠黏膜炎的保护作用
Xuan-Ying Wang,Bo Zhang,Yi Lu et al.
Xuan-Ying Wang et al.
Although first-line chemotherapy drugs, including 5-fluorouracil (5-FU), remain one of the major choice for cancer treatment, the clinical use is also accompanied with dose-depending toxicities, such as intestinal mucositis (IM), in cancer ...
A Novel Insight into the Role of PLA2R and THSD7A in Membranous Nephropathy [0.03%]
PLA2R和THSD7A在膜性肾病中作用的新见解
Pingna Zhang,Weijun Huang,Qiyan Zheng et al.
Pingna Zhang et al.
Membranous nephropathy (MN) is an organ-restricted autoimmune disease mainly caused by circulating autoantibodies against podocyte antigens, including the M-type phospholipase A2 receptor (PLA2R) and thrombospondin domain-containing 7A (THS...
Exosomes Derived from Nerve Stem Cells Loaded with FTY720 Promote the Recovery after Spinal Cord Injury in Rats by PTEN/AKT Signal Pathway [0.03%]
神经干细胞衍生的装载FTY720的外泌体通过PTEN/AKT信号途径促进脊髓损伤后的恢复
Jianbin Chen,Can Zhang,Shouye Li et al.
Jianbin Chen et al.
Background: Spinal cord injury (SCI) remains a challenge owing to limited therapies. The exosome of neural stem cells (NSCs-Exos) and FTY720 transplantation could improve SCI effectively. However, the effect and mechanism...
Shunyu Yao,Zixi Zhao,Weijun Wang et al.
Shunyu Yao et al.
The prevalence of inflammatory bowel disease (IBD), which includes ulcerative colitis (UC) and Crohn's disease (CD), increases gradually worldwide in the past decades. IBD is generally associated with the change of the immune system and gut...