Yao Tian,Hongyi Yang,Na Liu et al.
Yao Tian et al.
Sjögren's syndrome (SS) is a chronic autoimmune disease of unknown etiology that mainly involves exocrine glands. Patients present with dry mouth and eyes, fever, arthralgia, and other systemic symptoms. In severe cases, the quality of lif...
Elevated Natural Killer Cell-Mediated Cytotoxicity Is Associated with Cavity Formation in Pulmonary Tuberculosis Patients [0.03%]
肺结核患者细胞毒作用增强的自然杀伤细胞与空洞形成有关
Shanshan Li,Dongpo Wang,Panjian Wei et al.
Shanshan Li et al.
Cavitation is a major pathological feature of pulmonary tuberculosis (TB). The study is aimed at investigating the mechanism of natural killer (NK) cells participating the cavity formation during Mycobacterium tuberculosis (MTB) infection. ...
Observational Study
Journal of immunology research. 2021 Oct 4:2021:7925903. DOI:10.1155/2021/7925903 2021
Nicotine Exacerbates TAAD Formation Induced by Smooth Muscle-Specific Deletion of the TGF- β Receptor 2 [0.03%]
烟碱加剧由平滑肌TGF-β受体2特异性缺失诱导的TAAD形成
Changzoon Chun,Xiaoyan Qi,Fen Wang et al.
Changzoon Chun et al.
Tobacco smoke is an established risk factor for thoracic aortic aneurysms and dissections (TAAD). However, little is known about its underlying mechanisms due to the lack of validated animal models. The present study developed a mouse model...
Justyna Sakowska,Paulina Glasner,Maciej Zieliński et al.
Justyna Sakowska et al.
Cornea is one of the most commonly transplanted tissues worldwide. However, it is usually omitted in the field of transplantology. Transplantation of the cornea is performed to treat many ocular diseases. It restores eyesight significantly ...
HIV-Related Immune Activation and Inflammation: Current Understanding and Strategies [0.03%]
HIV相关免疫激活和炎症：当前的理解与策略
Tingxia Lv,Wei Cao,Taisheng Li
Tingxia Lv
Although antiretroviral therapy effectively controls human immunodeficiency virus (HIV) replication, a residual chronic immune activation/inflammation persists throughout the disease. This aberrant immune activation and inflammation are con...
circCOL1A1 Promotes the Progression of Gastric Cancer Cells through Sponging miR-145 to Enhance RABL3 Expression [0.03%]
circCOL1A1通过吸附miR-145促进胃癌细胞的进展从而增强RABL3的表达
Yue Ma,Yanyi Ren,Huitao Wen et al.
Yue Ma et al.
Circular RNA has been reported to be a new noncoding RNA which plays important roles in tumor progression. One of the most common functions of circular RNA is to regulate microRNA expression by acting as a microRNA sponge. However, the circ...
Increased Circulating CD4+CXCR5+ Cells and IgG4 Levels in Patients with Myelodysplastic Syndrome with Autoimmune Diseases [0.03%]
患有自身免疫性疾病的骨髓增生异常综合征患者循环CD4+CXCR5+细胞及IgG4水平升高
Na Xiao,Xin He,Haiyue Niu et al.
Na Xiao et al.
Objectives: Immune abnormalities play an important role in the pathogenesis and progression of myelodysplastic syndrome (MDS). Some patients with MDS have autoimmune diseases (AI). Follicular helper T (Tfh) cells help B c...
Integrated Bioinformatics and Experimental Approaches Identified the Role of NPPA in the Proliferation and the Malignant Behavior of Breast Cancer [0.03%]
整合生物信息学和实验方法揭示NPPA在乳腺癌增殖及恶性行为中的作用
Aijun Sun,Xiaonan Sheng,Jinhai Tang et al.
Aijun Sun et al.
Breast cancer is the 3rd most common type of malignant tumor worldwide with high heterogeneity, frequent recurrence, and high metastasis tendency. In this study, we aimed to demonstrate the value of extracellular matrix- (ECM-) related gene...
Inhaled [D-Ala2]-Dynorphin 1-6 Prevents Hyperacetylation and Release of High Mobility Group Box 1 in a Mouse Model of Acute Lung Injury [0.03%]
吸入[D-ala2]- Dynorphin 1-6可防止急性肺损伤小鼠模型中高迁移率族盒1的过度乙酰化和释放
Vladislav N Karkischenko,Veronika I Skvortsova,Melik T Gasanov et al.
Vladislav N Karkischenko et al.
COVID-19 is a respiratory infection caused by the SARS-CoV-2 virus that can rapidly escalate to life-threatening pneumonia and acute respiratory distress syndrome (ARDS). Recently, extracellular high mobility group box 1 (HMGB1) has been id...
Meng Wang,Bo Zhang
Meng Wang
Exosomes are lipid bilayer particles that originated from almost all types of cells and play an important role in intercellular communication. Tumor-derived exosomes contain large amounts of noncoding RNA, DNA, and proteins, which can be tr...