Metabolic Reprograming of Macrophages: A New Direction in Traditional Chinese Medicine for Treating Liver Failure [0.03%]
代谢重编程与巨噬细胞极化：中医药治疗肝衰竭的新方向
Junli Zhang,Na Li,Xiaoyu Hu
Junli Zhang
Acute liver failure (ALF) is a fulminant clinical syndrome that usually leads to multiple organ failure and high mortality. Macrophages play a crucial role in the initiation, development, and recovery of ALF. Targeting macrophages through i...
Identification of Hub Biomarkers and Immune and Inflammation Pathways Contributing to Kawasaki Disease Progression with RT-qPCR Verification [0.03%]
基于RT-qPCR验证的参与川崎病进展的关键生物标志物和免疫炎症通路识别
Hongjun Ba,Lili Zhang,Huimin Peng et al.
Hongjun Ba et al.
Background: Kawasaki disease (KD) is characterized by a disordered inflammation response of unknown etiology. Immune cells are closely associated with its onset, although the immune-related genes' expression and possibly ...
Inhibition of Oxidative Stress-Induced Ferroptosis Can Alleviate Rheumatoid Arthritis in Human [0.03%]
抑制氧化应激诱导的铁死亡可改善人类类风湿性关节炎
Yang Liu,Jiang Liang,Zongge Sha et al.
Yang Liu et al.
Rheumatoid arthritis (RA) is a chronic autoimmunity illness, mainly featured with synovitis of the joint. The specificity of ferroptosis is disparate in different diseases, and the mechanism of ferroptosis in RA has some uncertainty yet. Th...
Manual Therapy Exerts Local Anti-Inflammatory Effects Through Neutrophil Clearance [0.03%]
手法治疗通过清除中性粒细胞发挥局部抗炎作用
Hongwen Liu,Shiguo Yuan,Kai Zheng et al.
Hongwen Liu et al.
Background: Manual therapy (MT) has been widely used in China to treat local tissue inflammation for a long time. However, there is a lack of scientific evidence for using MT in anti-inflammatory therapy, and its anti-inflammatory mechanism...
Construction of the miRNA/Pyroptosis-Related Molecular Regulatory Axis in Abdominal Aortic Aneurysm: Evidence From Transcriptome Data Combined With Multiple Machine Learning Approaches Followed by Experiment Validation [0.03%]
基于转录组数据构建腹主动脉瘤中miRNA/焦亡相关分子调控轴：多种机器学习方法结合实验验证证据
Yongchao Su,Chuangang Lu,Shuchen Chen
Yongchao Su
Background: Abdominal aortic aneurysm (AAA) represents a permanent and localized widening of the abdominal aorta, posing a potentially lethal risk of aortic rupture. Several recent studies have highlighted the role of pyroptosis, a pro-infl...
Agreement of Peru-Based Allergy Tests for Respiratory Allergens in Allergic Rhinitis Patients [0.03%]
基于秘鲁的过敏测试在过敏性鼻炎患者中的呼吸过敏原的一致性研究
César Galván,Margarita Totesaut,Edgar Muñoz et al.
César Galván et al.
Background: The Peruvian Immunoblot panel, together with traditional skin prick tests (SPT), are widely used in vitro allergy tests in Peru. In addition to this, Peruvian allergists are increasingly adopting multiplex tes...
Virus-Triggered Autoimmunity Was Associated With Hirschsprung's Disease Through Activation of Innate Immunity [0.03%]
病毒触发的自身免疫通过激活先天性免疫与Hirschsprung病相关联
Weiyong Zhong,Chaoting Lan,Yuqiong Chen et al.
Weiyong Zhong et al.
Background: Hirschsprung's disease (HSCR) is a congenital enteric nervous system (ENS) disorder. Genetics cannot explain most sporadic cases. To explore the relationship between pathogen infection, autoantibodies, innate immune, and HSCR. M...
Exercise Attenuates Doxorubicin-Induced Myocardial Injury by Inhibiting TSHR and Regulating Macrophage Polarization Through miR-30d-5p/GALNT7 [0.03%]
运动通过miR-30d-5p/GALNT7抑制TSHR调节巨噬细胞极化从而缓解多柔比星诱导的心肌损伤
Haiyan Wu,Ruoyu Zhou,Hanxin Kong et al.
Haiyan Wu et al.
Objective: Doxorubicin (DOX) is an extensively used chemotherapeutic agent that induces cardiotoxicity. Studies have reported that exercise (EXE) can alleviate DOX-induced cardiotoxicity. Therefore, this study aimed to explore the mechanism...
Tumour Immunotherapy and Applications of Immunological Products: A Review of Literature [0.03%]
肿瘤免疫治疗及免疫学产品应用的研究进展
Angus Nnamdi Oli,Samson Adedeji Adejumo,Adekunle Babajide Rowaiye et al.
Angus Nnamdi Oli et al.
Malignant tumors, characterized by uncontrolled cell proliferation, are a leading global health challenge, responsible for over 9.7 million deaths in 2022, with new cases expected to rise to 35 million annually by 2050. Immunotherapy is pre...
Mitochondrial Quality Control Orchestrates the Symphony of B Cells and Plays Critical Roles in B Cell-Related Diseases [0.03%]
线粒体质量控制在B细胞功能中的作用及其在B细胞相关疾病中所扮演的重要角色
Wuhao Li,Peiyang Cai,Ye Xu et al.
Wuhao Li et al.
B cells are essential for humoral immune response due to their ability to secrete antibodies. The development of B cells from the bone marrow to the periphery is tightly regulated by a complex set of immune signals, and each subset of B cel...