The Impact of Monkeypox Virus Infection on Pregnancy Outcome: Clinical Features and Potential Pathogenic Mechanisms [0.03%]
猴痘病毒感染对妊娠结局的影响：临床特征及可能的致病机制
Jingyi Wu,Fangbin Huang,Qingliang Zheng
Jingyi Wu
Monkeypox has garnered significant attention following its emergence in multiple countries and its designation as a global health emergency in 2022. There is a notable deficiency in clinical and experimental data regarding pregnancy outcome...
Myeloid-Derived Suppressor Cells: Immunoregulatory Roles and Therapeutic Prospects in Immune-Mediated Hematological Disorders [0.03%]
髓源抑制细胞在免疫介导的血液系统疾病中的免疫调节作用及治疗前景
Qi Liu,Kunpeng Zhang,Shun He et al.
Qi Liu et al.
Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of immature myeloid cells that have been increasingly defined and characterized over the past two decades, known for their remarkable capacity to expand and exert immun...
CD47 Expression in Classic Hodgkin Lymphoma and Its Association With Tumor Microenvironment [0.03%]
经典霍奇金淋巴瘤中的CD47表达及其与肿瘤微环境的关系研究
Xiaoyue Xiao,Lin Nong,Yiyang Luo et al.
Xiaoyue Xiao et al.
Cluster of differentiation 47 (CD47) has been reported to overexpress in various malignant tumors and is associated with inferior prognosis. However, the critical role of CD47 in classic Hodgkin lymphoma (CHL) and its association with immun...
CD39 Expression in Peripheral CD4+ T Lymphocytes Is Associated With Disease Activity in Patients With Systemic Lupus Erythematosus [0.03%]
外周血CD4+T淋巴细胞CD39表达与系统性红斑狼疮病情活动度的关系
Hao Jin,Lu Tang
Hao Jin
Objective: Regulatory T cells (Tregs) and CD4-positive T cells are crucial for the immunological control of systemic lupus erythematosus (SLE). As a crucial component of the adenosine metabolism pathway, CD39 influences t...
Lnc-CHRM4-2:1 Inhibits M2 Polarization and Efferocytosis of Macrophages by Downregulating MerTK and SLC2A1 in Rheumatoid Arthritis [0.03%]
长链非编码RNA Lnc-CHRM4-2:1通过下调MerTK和SLC2A1抑制类风湿关节炎中巨噬细胞M2极化及胞葬作用
Jinjin Chu,Jie Zang,Lili Zhang et al.
Jinjin Chu et al.
Objective: Rheumatoid arthritis (RA) is a common chronic and systemic autoimmune disease. Long noncoding RNAs (lncRNAs) have been documented to play important roles in the pathogenesis of RA. This study is aimed to invest...
Cytokine Signatures Outperform Immune Subsets in Machine Learning Models for Predicting Acute Graft-Versus-Host Disease at Neutrophil Engraftment [0.03%]
细胞因子谱优于免疫亚群：预测中性粒细胞植入的机器学习模型
Mohini Mendiratta,Praful Pandey,Shobhit Pandey et al.
Mohini Mendiratta et al.
Background: Acute graft-versus-host disease (aGvHD) is a major immune complication of allogeneic hematopoietic stem cell transplantation (Allo-HSCT), driven by complex immune-cytokine interactions. This study employed mac...
The Abnormal Expression of B7-H4 Is Associated With the Pathogenesis of Autoimmune Thyroid Diseases [0.03%]
B7-H4异常表达与自身免疫性甲状腺疾病发病机制的相关性研究
Yuqing Wu,Jianbin Xu,TianTian Cai et al.
Yuqing Wu et al.
Background: B7-H4 is an immunosuppressive molecule extensively studied in tumor diseases and is also of interest in some autoimmune diseases. However, the relationship between B7-H4 and autoimmune thyroid diseases (AITDs)...
Next-Generation Immune Checkpoints and Tumor Microenvironment Modulation in Cancer Immunotherapy [0.03%]
癌症免疫治疗中的下一代免疫检查点和肿瘤微环境调控
Jhommara Bautista,Carolina E Echeverría,Iván Maldonado-Noboa et al.
Jhommara Bautista et al.
Immunotherapy has reshaped the oncology landscape by enabling the immune system to recognize and eliminate malignant cells. Although immune checkpoint inhibitors (ICIs) targeting cytotoxic T-lymphocyte-associated protein 4 (CTLA-4), program...
Xin Liu,Mingyu Yu,Pan Zou et al.
Xin Liu et al.
Psoriasis is a chronic inflammatory skin disease characterized by abnormal proliferation of epidermal cells induced by an overactive immune system. In addition to the interaction between immune cells and keratinocytes, emerging research hig...
Epigenetic Modulation of IL-7 and IL-10: Toward Personalized Immune Therapies in Viral Epidemics [0.03%]
表观遗传调控IL-7和IL-10：面向病毒流行中个体化免疫治疗的研究
Zerrin Yulugkural,Mustafa Yildiz,Ertugrul Topcu et al.
Zerrin Yulugkural et al.
Background: Host immune responses, including cytokine production, shape the severity of viral epidemics. Epigenetic mechanisms such as DNA methylation regulate cytokine gene expression and may contribute to immune dysregu...