Associations Between Immune Senescence and Immune Reconstitution Among People Living With HIV Undergoing Antiretroviral Therapy [0.03%]
HIV感染者接受抗逆转录病毒治疗人群的免疫衰老与免疫重建之间的关联性研究
Zhe Qian,Huolan Long,Houji Wu et al.
Zhe Qian et al.
Background: Failure of immune reconstitution (IR), characterized by suboptimal CD4+ T-cell recovery despite virologic suppression on antiretroviral therapy (ART), remains a critical challenge for people living with human ...
Evaluating Drug-Target Complexes in Therapeutic Monoclonal Antibodies Using A4F-MALS: Implications for Drug Development and Clinical Design [0.03%]
用于治疗性单克隆抗体药物-靶点复合物评价的A4F-MALS研究及其对新药研发和临床试验设计的意义分析研究论文
Nina Liu,Donald Kotowski,Eric T Ong et al.
Nina Liu et al.
Therapeutic monoclonal antibodies (mAbs) remain an important segment of the biopharmaceutical industry, delivering highly effective and targeted responses against human diseases. The immune complexes formed between a therapeutic mAb and its...
Comparison of Serum TARC Levels at Term-Equivalent Age Between Preterm and Term Infants [0.03%]
早产儿与足月儿矫正胎龄足月时血清TARC水平的比较
Ayako Goto,Kei Kubota,Takashi Sakaguchi et al.
Ayako Goto et al.
Objective: Preterm infants have a lower incidence of allergies; however, data on serum levels of thymus and activation-regulated chemokine (TARC/CCL17) are limited. We aimed to compare serum TARC levels at term-equivalent...
Comparative Study
Journal of immunology research. 2026;2026(1):e3984014. DOI:10.1155/jimr/3984014 2026
Tfh Cells in Henoch-Schönlein Purpura (IgA Vasculitis): Current Concept [0.03%]
Henoch-Schönlein紫癜(IgA血管炎)中的TFH细胞:当前概念
Junke Huang,Juan Liu,Yue Hu et al.
Junke Huang et al.
Henoch-Schönlein purpura (HSP) is an inflammatory condition affecting the small blood vessels, leading to organ damage and symptoms across various body systems, including skin, joints, and kidneys. The disease's pathogenesis involves the d...
Research Progress on the Mechanism of Ginsenoside Rg1 in Inflammatory Bowel Disease [0.03%]
红参皂苷Rg1改善肠道炎症机制的研究进展
Dandan Liang,Shaolei Yang,Dehuai Jing et al.
Dandan Liang et al.
Inflammatory bowel disease (IBD), a chronic intestinal inflammatory disorder, has witnessed a rising incidence globally. At present, the primary therapeutic approaches for IBD, such as aminosalicylic acid, glucocorticoids, immunosuppressant...
Deciphering the Underlying Mechanisms Linking Psoriasis and IgA Nephropathy [0.03%]
探究银屑病和IgA肾病之间的内在联系机制
Zijie Tang,Jintong Wu,Meihan Dong et al.
Zijie Tang et al.
Psoriasis is a chronic, immune-mediated inflammatory disease with systemic manifestations that include renal complications. Immunoglobulin A nephropathy (IgAN) represents the most common autoimmune glomerular disease worldwide. Growing epid...
RETRACTION: Microglia Play a Major Role in Direct Viral-Induced Demyelination [0.03%]
撤稿：小胶质细胞在直接病毒诱导的脱髓鞘中扮演主要角色
Journal Of Immunology Research
Journal Of Immunology Research
High Fat Diet-Induced Obesity Alters Cutaneous Immune Cell Function, and These Changes Persist After Weight Loss [0.03%]
高脂饮食诱导的肥胖改变了皮肤免疫细胞的功能，并且在减肥后这些变化会持续存在
Wakana Kamada,Hiromasa Tanno,Rena Takayashiki et al.
Wakana Kamada et al.
Obesity is recognized as a chronic low-grade inflammation that contributes to metabolic disorders. Weight loss (WL) is well known to improve metabolic disorders. However, recent studies have shown that the changes in immune cells associated...
Induction of HIV-Specific T Cell Responses Using αDC1 Pulsed With Conserved HIV-1 Peptides [0.03%]
使用包被了HIV-1肽的αDC1诱导HIV特异性T细胞免疫应答
Laís Teodoro Da Silva,Marina Mazzilli Ortega,Silvia de Jesus Mota et al.
Laís Teodoro Da Silva et al.
Despite the effectiveness of antiretroviral therapy (ART) in suppressing HIV-1 replication and reducing morbidity, viral eradication remains unachievable due to the persistence of latent reservoirs, particularly within memory CD4+ T cells. ...
Induced Regulatory T Cells Attenuate Poly I:C-Triggered Acute Lung Injury by Modulating Cytokine Responses [0.03%]
诱导产生的调节性T细胞通过调控细胞因子反应缓解聚肌苷聚胞苷酸引起的急性肺损伤
Chun-Hsien Hsu,Win-Chin Chiang,Shau-Kwaun Chen et al.
Chun-Hsien Hsu et al.
Background and objective: Acute lung injury (ALI) is characterized by severe pulmonary inflammation and edema and carries a high risk of mortality. This study aimed to evaluate the therapeutic potential of induced regulat...