Epigenetic Regulation of B Cell Memory Formation: A Poised Model for B Cell Epigenetic Reprograming [0.03%]
B细胞记忆形成表观遗传调控:B细胞表观重编程的准备模型
Carlos Valverde-Hernandez
Carlos Valverde-Hernandez
The formation of B cell immunological memory happens after the first encounter with a pathogen. At the germinal center (GC), B cells experience complex transcriptional and epigenetic transitions to differentiate into memory B cells (MBCs) a...
Erratum to "Global Trends in Research of Amino Acid Metabolism in T Lymphocytes in Recent 15 Years: A Bibliometric Analysis" [0.03%]
关于“近15年T淋巴细胞氨基酸代谢研究的全球趋势变化：基于文献计量学的分析”的勘误通知
[This corrects the article DOI: 10.1155/jimr/3393342.]. Copyright © 2025 Journal of Immunology Research published by John Wiley & Sons Ltd.
Published Erratum
Journal of immunology research. 2025 Jun 24:2025:9813495. DOI:10.1155/jimr/9813495 2025
Integrated Transcriptomic Analysis Provided Diagnostic and Pathophysiological Insights for Epilepsy [0.03%]
整合转录组分析为癫痫的诊断和病理生理学提供了见解
Shuang Li,Zhigang Wang,Yake Zheng et al.
Shuang Li et al.
Background: Epilepsy is a common neurological disorder involving multiple genes and molecular pathways. Study of differentially expressed genes (DEGs) and hub genes related to epilepsy can help reveal the pathophysiologic basis and improve ...
Poxvirus Vectors Activate Human NK and MAIT Cells in a Type I Interferon, IL-18, and Monocyte-Dependent Manner [0.03%]
痘病毒载体通过I型干扰素、IL-18和单核细胞依赖的方式活化人体NK细胞和MAIT细胞
Kombo F N&#x;guessan,Zhanna Shubin,Kawthar Machmach et al.
Kombo F N&#x;guessan et al.
Recombinant poxviruses have been extensively studied as vaccine vectors, yet the specific mechanisms by which they engage the immune system remain incompletely understood. ALVAC is a poxviral vector that was a component of the HIV vaccine u...
4-Phenyl Butyric Acid (4-PBA) Suppresses Neutrophil Recruitment in a Murine Model of Acute Perinatal Inflammation [0.03%]
苯基丁酸抑制急性围产期炎症小鼠模型中性粒细胞募集作用
Christian Gille,Maylis Jungwirth,Silvia Pezer et al.
Christian Gille et al.
Neutrophils are the first immune cells to be recruited to the site of infection and deregulated activation is linked to adverse outcome, especially in premature neonates. Dampening neutrophil activity may therefore be a means of preventing ...
The Multifaceted Role of the IL-2 Cytokine Family in Melanoma: Mechanisms, Therapeutic Implications, and Immune Modulation [0.03%]
细胞因子家族在黑色素瘤中的多面作用：机制、治疗意义和免疫调节
Mona Daghaighei,Samaneh Dodge,Soheil Bolandi et al.
Mona Daghaighei et al.
Background and Objective: Melanoma is a complex malignancy where the interplay between immune cells, cytokines, and the tumor microenvironment (TME) significantly influences disease progression and patient outcomes. This review explores the...
Longitudinal Analysis of Traditional Inflammatory Markers (IL-6, CRP) Juxtaposed With Heparin-Binding Protein (HBP) and Serum Amyloid A Protein Component (SAA) During Acute Infection and Convalescence From COVID-19 Infection in the Context of Initial Viral Load and Markers of Tissue Destruction [0.03%]
急性COVID-19感染及后期康复过程中，结合初始病毒载量和组织破坏标志物纵向分析传统炎症标记物（IL-6、CRP）与肝素结合蛋白（HBP）和血清淀粉样蛋白A组分（SAA）的情况
Ahmed Sayed Ahmed,Mohamed A Mahmoud,Hossam Gad et al.
Ahmed Sayed Ahmed et al.
Purpose: Characterization of immune system heterogeneity in COVID-19 patients by comparing the inflammatory markers heparin-binding protein (HBP), serum amyloid A protein (SAA), IL-6, and C-reactive protein (CRP) in relation to viral burden...
Macrophage Transcriptomic Alterations Driven by Alphavirus-Based Cancer Immunotherapy Vectors [0.03%]
基于α病毒的癌症免疫治疗载体驱动的巨噬细胞转录组变化
Ksenija Korotkaja,Darija Lapina,Zhanna Rudevica et al.
Ksenija Korotkaja et al.
Cancer cells promote the polarisation of tumour-associated macrophages (TAMs) into pro-tumorigenic M2-like phenotype, contributing to cancer progression. Reprogramming TAMs by viral immunotherapy vectors represents a promising strategy for ...
The Molecular Mechanisms of Imatinib Treatment on Acute Lung Injury in Septic Mice Through Proteomic Technology [0.03%]
基于蛋白质组学技术探讨伊马替尼治疗脓毒症小鼠急性肺损伤的分子机制研究
Xiao Wang,ZhiQing Zhou,DuanYang Li et al.
Xiao Wang et al.
Background: Acute lung injury (ALI) is the most common complication of sepsis. Despite considerable progress in the treatment of sepsis, the effective treatment strategies are lacking. A previous study has shown that imatinib reduces the ra...
Roles of Mitochondrial Fusion and Division in Harmine Derivative H-2-168-Induced Neurotoxicity [0.03%]
害拉明衍生物H-2-168诱导神经毒性的线粒体融合与分裂作用研究
Yuehong Gong,Meichi Pan,Hang Ren et al.
Yuehong Gong et al.
Background: Harmine (HM) has several pharmacological effects; however, severe neurotoxicity limits its clinical application and development. HM neurotoxicity is associated with abnormal energy metabolism. This study aimed to explore the rol...