Coordination Between Treg Cells and Bifidobacterium in the Immune-Bacterial Network of Human Colostrum [0.03%]
人类初乳免疫-细菌网络中Treg细胞与双歧杆菌的相互作用
Mextli Y Bermejo-Haro,Graciela Hernández-Peláez,Ivonne J Álvarez-Peña et al.
Mextli Y Bermejo-Haro et al.
Breast milk is the primary source of nutrients, bacterial, and defensive elements, which are required for infants in their first years of life. Colostrum, the first stage of breast milk, contains abundant levels of antibodies, lymphocytes, ...
Allergic Sensitization to Common Ragweed and Mugwort Pollen Allergens: A 6-Year Single-Center Retrospective Analysis [0.03%]
对常见艾属和蒿属花粉过敏原过敏敏感性：一项6年的单中心回顾性分析
Zhipeng Zhao,Runqing Li,Rui Li et al.
Zhipeng Zhao et al.
Objective: Based on a 6-year longitudinal monitoring of specific immunoglobulin E (sIgE) responses to common ragweed (Ambrosia, Ambrosia artemisiifolia) and mugwort (Artemisia, Artemisia vulgaris) pollen allergens, this s...
Local and Systemic Immunologic Profiles Differentiate Accepted and Rejected Islet Grafts in a Rat Anterior Chamber Model [0.03%]
局部和全身免疫谱型可区分大鼠眼前房异体移植胰岛的接受与排斥反应
Jae-Young Lee,Choun-Ki Joo,Asif I Shawl et al.
Jae-Young Lee et al.
The anterior chamber of the eye (ACE) provides a minimally invasive, immune-privileged site for pancreatic islet engraftment. However, loss of immune privilege during revascularization can trigger inflammation and graft rejection. In this s...
Multicenter Analytical Comparison of Automated Quantitative Assays Versus Line Immunoassay for Anti-Ro/La Antibody Detection in Primary Sjögren's Syndrome [0.03%]
多中心定量检测与线性免疫印迹法检测原发性舍格伦综合征抗Ro/ La抗体的对比研究
Yu-Lan Chen,Chao-Jun Hu,Lin-Yi Peng et al.
Yu-Lan Chen et al.
Objective: This multicenter study aimed to analytically compare the performance of automated quantitative assays-chemiluminescence immunoassay (CLIA) and multiplexed bead immunoassay (MBI)-for detecting anti-Ro/La antibod...
Comparative Study
Journal of immunology research. 2026;2026(1):e9771858. DOI:10.1155/jimr/9771858 2026
The Role of BMAL1 in Regulating Circadian Rhythms During Airway Remodeling in Asthma [0.03%]
BMAL1在哮喘气道重塑过程中调节生物钟节律的作用
Xiaorong Xiang,Caiming Zhong,Hao Tang
Xiaorong Xiang
Asthma is a chronic respiratory disease characterized by airway inflammation, hyperresponsiveness, and remodeling. The circadian clock governs natural 24 h biological rhythms, encompassing physiological, metabolic, and hormonal fluctuations...
Metabolic Reprogramming of T Cells by MSCs Rebalances Th17/Treg Axis to Attenuate Collagen-Induced Arthritis [0.03%]
间充质干细胞重塑T细胞代谢以重构Th17/Treg平衡从而抑制自身免疫关节炎
Xiaoping Wang,Jingjing He,Qun Wang et al.
Xiaoping Wang et al.
Background: Rheumatoid arthritis (RA) is a chronic autoimmune disorder characterized by dysregulated T cell responses and metabolic disturbances. Mesenchymal stromal cells (MSCs) have shown therapeutic promise, but their ...
Si Shen,Zhonghao Tang,Chen Guo et al.
Si Shen et al.
Prostate cancer (PCa) is a major global cancer burden in men, and its treatment is hindered by the immunosuppressive tumor microenvironment. In this context, PCa initially shows a favorable response to immunotherapy. However, as the disease...
Chaiyin Granules Improve Acute Lung Injury by Regulating Gut Microbiota and Unsaturated Fatty Acid Mediated Wnt/β-Catenin Signaling Pathway [0.03%]
柴银颗粒通过调节肠道菌群及不饱和脂肪酸介导的Wnt/β-catenin信号通路改善急性肺损伤
Wenting Ni,He Xiao,Qun Feng et al.
Wenting Ni et al.
Aim of study: This study aimed to investigate the efficacy and mechanism of Chaiyin granules (CY) in improving acute lung injury (ALI) based on the gut-lung axis. ...
Characteristic Changes in the Immune Landscape of Aging Liver: From Basic Mechanism to Clinical Transformation [0.03%]
衰老肝脏免疫景观的特征性变化：从基本机制到临床转化研究进展
Tong Zhu,Aijing Xu,Wei Yin et al.
Tong Zhu et al.
The global population is aging at an unprecedented rate, significantly increasing the burden of age-related liver diseases. While the mechanisms of liver aging remain incompletely understood, immune senescence within the hepatic microenviro...
IL-27: A Double-Edged Sword in Immune Regulation via JAK-STAT Orchestration [0.03%]
通过JAK-STAT调节的免疫调控中的双刃剑IL-27
Xiangqi Zhang,Chen Feng,Ye Xu et al.
Xiangqi Zhang et al.
Interleukin-27 (IL-27) is a multifunctional cytokine produced mainly by innate immune cells that regulates immune responses primarily through the Janus kinase (JAK)-signal transducer and activator of transcription (STAT) signaling pathway. ...