Bissene Douma,Thouraya Ben Younes,Hanene Benrhouma et al.
Bissene Douma et al.
Background: Autoimmune encephalitis (AE) is a rapidly progressive encephalopathy caused by antibodies targeting neurons in the central nervous system generating specific immune responses. It is increasingly recognized in ...
Upregulation of lnc-ZNF281 Inhibits the Progression of Glioma via the AKT/GSK-3 β/ β-Catenin Signaling Pathway [0.03%]
长链非编码RNA lnc-ZNF281通过AKT/GSK-3β/β-catenin信号通路抑制胶质瘤进展
Yu-Qin Deng,Gang-Yong Kong,Song Li et al.
Yu-Qin Deng et al.
The purpose of this study is to elucidate the roles and potential underlying mechanisms of long noncoding RNA lnc-ZNF281 in glioma. We performed qRT-PCR to detect the expression levels of lnc-ZNF281 in glioma tissues. The effects of lnc-ZNF...
Observational Study
Journal of immunology research. 2021 May 11:2021:5573071. DOI:10.1155/2021/5573071 2021
Induction of Humoral and Cellular Immunity by Intradermal Delivery of SARS-CoV-2 Nucleocapsid Protein Using Dissolvable Microneedles [0.03%]
用于递送SARS-CoV-2核衣壳蛋白的可溶性微针诱导体液和细胞免疫反应
Chaiyaporn Kuwentrai,Jinming Yu,Bao-Zhong Zhang et al.
Chaiyaporn Kuwentrai et al.
The nucleocapsid protein (NP) of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) contains immunogenic epitopes that can induce cytotoxic T lymphocyte (CTL) against viral infection. This makes the nucleocapsid protein a suit...
Neuroprotective Effects of Asparagus officinalis Stem Extract in Transgenic Mice Overexpressing Amyloid Precursor Protein [0.03%]
华法芦笋茎提取物对APP转基因小鼠的神经保护作用
Zhanglong Peng,Supinder Bedi,Vivek Mann et al.
Zhanglong Peng et al.
To mimic Alzheimer's disease, transgenic mice overexpressing the amyloid precursor protein (APP) were used in this study. We hypothesize that the neuroprotective effects of ETAS®50, a standardized extract of Asparagus officinalis stem prod...
Increased TNF- α Initiates Cytoplasmic Vacuolization in Whole Blood Coculture with Dengue Virus [0.03%]
增高的TNF- α介导的登革病毒全血共培养细胞浆气球样变性形成增多
Rahmat Dani Satria,Tzu-Wen Huang,Ming-Kai Jhan et al.
Rahmat Dani Satria et al.
During the acute febrile phase of dengue virus (DENV) infection, viremia can cause severe systemic immune responses accompanied by hematologic disorders. This study investigated the potential induction and mechanism of the cytopathic effect...
Observational Study
Journal of immunology research. 2021 May 6:2021:6654617. DOI:10.1155/2021/6654617 2021
Epitope-Based Peptide Vaccine Design against Fructose Bisphosphate Aldolase of Candida glabrata: An Immunoinformatics Approach [0.03%]
基于免疫信息学的葡萄糖醛酸单胞菌fructose bisphosphate aldol酶表位肽疫苗设计
Lina Mohamed Elamin Elhasan,Mohamed B Hassan,Reham M Elhassan et al.
Lina Mohamed Elamin Elhasan et al.
Background: Candida glabrata is a human opportunistic pathogen that can cause life-threatening systemic infections. Although there are multiple effective vaccines against fungal infections and some of these vaccines are e...
Pleiotropic Effect of Hormone Insulin-Like Growth Factor-I in Immune Response and Pathogenesis in Leishmaniases [0.03%]
胰岛素样生长因子-Ⅰ在利什曼病免疫反应及发病中的多效性作用研究
Luiza C Reis,Eduardo Milton Ramos-Sanchez,Fernanda N Araujo et al.
Luiza C Reis et al.
Leishmaniases are diseases caused by several Leishmania species, and many factors contribute to the development of the infection. Because the adaptive immune response does not fully explain the outcome of Leishmania infection and considerin...
miR-183-5p Is a Potential Molecular Marker of Systemic Lupus Erythematosus [0.03%]
miR-183-5p可能是系统性红斑狼疮的潜在分子标志物
Shaolan Zhou,Jing Zhang,Pengfei Luan et al.
Shaolan Zhou et al.
Objective: To investigate microRNA (miRNA) expression profiles in individuals with systemic lupus erythematosus (SLE) and identify the valuable miRNA biomarkers in diagnosing and monitoring SLE. ...
Observational Study
Journal of immunology research. 2021 May 6:2021:5547635. DOI:10.1155/2021/5547635 2021
TASP1 Promotes Proliferation and Migration in Gastric Cancer via EMT and AKT/P-AKT Pathway [0.03%]
TASP1通过上皮间质转化及AKT/P-Akt通路促进胃癌的增殖和迁移
Xue-Mei Wan,Xue-Lei Zhou,Yong-Jun Du et al.
Xue-Mei Wan et al.
Threonine aspartase 1 (TASP1) was reported to function in the development of cancer. However, the regulatory mechanism of TASP1 in gastric cancer (GC) remains unclear. In this study, we determined the expression of TASP1 in tissues of GC pa...
Ursolic Acid Regulates Intestinal Microbiota and Inflammatory Cell Infiltration to Prevent Ulcerative Colitis [0.03%]
乌索林酸调节肠道微生物群和炎性细胞浸润以预防溃疡性结肠炎
Qinsong Sheng,Fei Li,Guanping Chen et al.
Qinsong Sheng et al.
Ulcerative colitis (UC) is a chronic and relapsing inflammatory bowel disorder in the colon and rectum leading to low life-quality and high societal costs. Ursolic acid (UA) is a natural product with pharmacological and biological activitie...