Investigating the Role of BAFF and Its Receptors in Renal Transplant Recipients with Chronic Antibody-Mediated Rejection [0.03%]
白细胞介素家族成员B细胞成熟剂在肾移植慢性抗体介导性排斥反应者中的作用及机制研究
Shima Afzali,Saeedeh Salehi,Abbas Shahi et al.
Shima Afzali et al.
Background: Kidney transplantation is the best treatment option for end stage renal disease (ESRD), but graft rejection is still a big obstacle that occurs in spite of immunosuppressive therapy. B cells are considered as ...
Neuromedin U Suppresses Collagen-Induced Arthritis through ILC2-Th2 Activation [0.03%]
神经调节素U通过ILC2-Th2活化抑制胶原诱导的关节炎
Yuanyuan Zhang,Yi Qin,Zhu Chen
Yuanyuan Zhang
Neuromedin U (NMU) is an evolutionarily conserved neuropeptide which was previously thought to have a proinflammatory property. Recently, it was reported that NMU induced rapid ILC2 activation and Th2 responses in allergic diseases. However...
Nicotinamide Ameliorates Dextran Sulfate Sodium-Induced Chronic Colitis in Mice through Its Anti-Inflammatory Properties and Modulates the Gut Microbiota [0.03%]
烟酰胺通过其抗炎特性改善小鼠慢性结肠炎并调节肠道微生物群
Kai Kang,Yue Sun,Dan Pan et al.
Kai Kang et al.
Vitamin B (nicotinamide (NAM)), one of the most important nutritional components for humans, exerts anti-inflammatory activity. This study was aimed at investigating the effect of NAM on the gut microbiota and short-chain fatty acids (SCFAs...
Increased Nuclear Transporter KPNA2 Contributes to Tumor Immune Evasion by Enhancing PD-L1 Expression in PDAC [0.03%]
核转运因子KPNA2促进PDAC中PD-L1表达并介导肿瘤免疫逃逸
Kai-Xia Zhou,Shan Huang,Li-Peng Hu et al.
Kai-Xia Zhou et al.
Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest malignancies and is known for its high resistance and low response to treatment. Tumor immune evasion is a major stumbling block in designing effective anticancer therapeutic s...
Corrigendum to "Hypoxia Impairs NK Cell Cytotoxicity through SHP-1-Mediated Attenuation of STAT3 and ERK Signaling Pathways" [0.03%]
“缺氧通过SHP-1介导的STAT3和ERK信号通路减弱抑制NK细胞细胞毒作用”一文中figure 5b的更正公告
Rui Teng,Yanmeng Wang,Nan Lv et al.
Rui Teng et al.
[This corrects the article DOI: 10.1155/2020/4598476.]. Copyright © 2021 Rui Teng et al.
Published Erratum
Journal of immunology research. 2021 Feb 25:2021:3625084. DOI:10.1155/2021/3625084 2021
Remote Limb Ischemic Postconditioning Protects against Ischemic Stroke via Modulating Microglia/Macrophage Polarization in Mice [0.03%]
远程肢体缺血后处理通过调节小胶质细胞/巨噬细胞极化保护小鼠免受卒中侵害
Dong Han,Jue Wang,Lulu Wen et al.
Dong Han et al.
Aim: The protection against ischemia/reperfusion injury mediated by remote limb ischemic postconditioning (RIPC) shows great clinical value in ischemic stroke therapy, but the particular mechanism of RIPC remains unclear....
The Heterogeneity of Neutrophil Recruitment in the Tumor Microenvironment and the Formation of Premetastatic Niches [0.03%]
肿瘤微环境中中性粒细胞募集的异质性和前转移 niches 的形成
Xin Xing,Yongrui Bai,Jian Song
Xin Xing
The recruitment of neutrophil to the primary cancer has been shown to be steered by neoplastic cells or tumor-educated mesenchymal stromal cells and has a prometastatic effect. However, the neutrophil chemotaxis and their interaction with t...
The Identification and Validation of a Robust Immune-Associated Gene Signature in Cutaneous Melanoma [0.03%]
用于黑色素瘤免疫相关基因标志物的鉴定与验证
Le-Bin Song,Jiao-Chen Luan,Qi-Jie Zhang et al.
Le-Bin Song et al.
Background: Cutaneous melanoma is defined as one of the most aggressive skin tumors in the world. An increasing body of evidence suggested an indispensable association between immune-associated gene (IAG) signature and me...
IL-13 Augments Histone Demethylase JMJD2B/KDM4B Expression Levels, Activity, and Nuclear Translocation in Airway Fibroblasts in Asthma [0.03%]
IL-13上调哮喘气道成纤维细胞JMJD2B/KDM4B表达、活性及核转位
Khuloud Bajbouj,Mahmood Y Hachim,Rakhee K Ramakrishnan et al.
Khuloud Bajbouj et al.
Purpose: Asthma is one of the most common obstructive pulmonary diseases worldwide. Epigenetic alterations, including DNA methylation and histone modifications, have been reported to contribute to asthma pathogenesis. Sin...
Hypoxia-Induced Autophagy Enhances Cisplatin Resistance in Human Bladder Cancer Cells by Targeting Hypoxia-Inducible Factor-1 α [0.03%]
缺氧诱导的自噬通过靶向低氧诱导因子-1α增强顺铂对人类膀胱癌细胞的耐药性
Xiawa Mao,Nanzhang,Jiaquao Xiao et al.
Xiawa Mao et al.
Purpose: To investigate the effect of hypoxia on chemoresistance and the underlying mechanism in bladder cancer cells. Methods: BIU-87 ...