Retinol Binding Protein 4 and Uric Acid as Risk Factors for Insulin Resistance in Type 2 Diabetes Mellitus [0.03%]
维生素D与血尿酸水平及其相互作用对2型糖尿病患者胰岛素抵抗的影响
Linyan Cheng,Liyan Wu,Tao-Hsin Tung et al.
Linyan Cheng et al.
Background: Hyperuricemia (HUA) is closely associated with insulin resistance (IR). Retinol-binding protein 4 (RBP4) plays a critical role in inducing IR. However, the combined effects of uric acid (UA) and RBP4 on IR rem...
Association of FTO rs9939609 Polymorphism With Obesity and Elevated Glycemic Parameters in a Syrian Population: A Case-Control Study [0.03%]
FTO基因多态性与叙利亚人群肥胖和高血糖参数的相关性:一项病例对照研究
Lana Wehbi,Shaden Haddad
Lana Wehbi
Background: Obesity is a major risk factor for Type 2 diabetes mellitus (T2DM), with substantial genetic determinants. The fat mass and obesity-associated (FTO) gene rs9939609 polymorphism has been consistently associated...
Long-Term Glycemic Control and Pharmacotherapy in Type 2 Diabetes Mellitus: A Descriptive Analysis of 10-Year Trends in a Statewide Sample [0.03%]
2型糖尿病的长期血糖控制及药物治疗:基于 statewide样本的10年变化描述性分析
Helen N Chen,Michael Weiner,Julian Wolfson et al.
Helen N Chen et al.
Background: Little is known about prescribing and glycemic control trends for Type 2 diabetes (T2D) drug classes across populations. Objective: ...
Identifying Diabetic Kidney Disease in Type 2 Diabetes Patients Using Explainable Machine Learning: A Case-Control Study [0.03%]
利用可解释机器学习识别2型糖尿病患者的糖尿病肾脏疾病:一项病例对照研究
Tongtong Qiu,Yi Bai,Hai Zhao et al.
Tongtong Qiu et al.
Objective: This research focused on establishing and testing a machine learning-driven predictive tool aimed at assisting in the identification of diabetic kidney disease (DKD). ...
Risk Stratification for Diabetic Kidney Disease Progression in Predicting All-Cause and Cardiovascular Mortality in Type 2 Diabetes: A National Cohort Study From NHANES 1999-2018 [0.03%]
基于NHANES(1999-2018)的全国队列研究:预测2型糖尿病患者全因死亡和心血管死亡的糖尿病肾病进展风险分层模型
Ying Qiu,Jun Jiang,Hongqiang Zhang et al.
Ying Qiu et al.
Diabetic kidney disease (DKD) substantially contributes to premature mortality in individuals with Type 2 diabetes (T2D). Although the 2024 American Diabetes Association (ADA) guideline incorporates the risk stratification of DKD progressio...
Metformin and Placental Ferroptosis in Gestational Diabetes: A Mechanistic Study [0.03%]
二甲双胍与妊娠糖尿病胎盘铁死亡的机制研究
Qiannan Lin,Xinyu Qin,Meihong Shen et al.
Qiannan Lin et al.
Gestational diabetes mellitus (GDM) is a major contributor to adverse pregnancy outcomes. Although the involvement of ferroptosis in GDM pathogenesis has been recognized, the precise mechanisms remain incompletely understood. This study is ...
Grape Exosome-Like Nanovesicles Reverse the Prediabetic State in Mice [0.03%]
葡萄类外体样纳米囊泡可逆转小鼠糖尿病前期状态
Zao-Ling Liu,Shu-Ya Cai,Aerna Qiayimaerdan et al.
Zao-Ling Liu et al.
Objective: This research explored the effect of grape exosome-like nanovesicles (GELNs) on reversing prediabetic conditions in mice and investigated the underlying mechanisms via metabolomic and gut microbiota analyses. ...
Caffeoylquinic Acids From Lonicera japonica Thunb. as Hypoglycemic Agents: Network Pharmacology and Pharmacological Validation [0.03%]
日本金银花 caffeoylquinic酸通过网络药理学及药理验证表明其具有降血糖活性
Yiyi Ye,Dawei Xu,Shilu Zhang et al.
Yiyi Ye et al.
The global increase in Type 2 diabetes (T2D) presents a serious public health challenge. Lonicera japonica Thunb., a traditional medicinal and edible plant, is a rich source of caffeoylquinic acids (CQAs), which are naturally occurring poly...
Achieving Diabetes Remission Through Dietary Intervention: A 12-Month Randomized Controlled Trial of Caloric-Carbohydrate Restriction in Overweight Patients With Early-Stage Type 2 Diabetes Mellitus [0.03%]
饮食干预实现糖尿病缓解:一项关于卡路里和碳水化合物限制对早期二型糖尿病超重患者的随机对照试验
Hongquan Wang,Qiong Wang,Jieqiong Chen et al.
Hongquan Wang et al.
Objective: We are aimed at evaluating the effects of a calorie-restricted low-carbohydrate diet (CR-LCD) on diabetes remission, weight control, and metabolic parameters in overweight patients with early-stage Type 2 diabe...
Randomized Controlled Trial
Journal of diabetes research. 2026;2026(1):e7230214. DOI:10.1155/jdr/7230214 2026
An Integrated Approach Combining Chemical Profiling, Network Pharmacology, and Experimental Validation Is Used to Clarify the Pharmacological Basis of the Yiqi-Tongluo-Huoxue-Mingmu Formula in Diabetic Retinopathy [0.03%]
整合化学谱图、网络药理学和实验验证的集成方法阐释益气通络活血明目法治疗糖尿病视网膜病变的作用物质基础
Yuan Gao,Qiang Lyu,Si-Wei Wang et al.
Yuan Gao et al.
Background: According to traditional Chinese medical (TCM) principles diabetic retinopathy (DR) is categorized as a type of "Wasting-Thirst Eye Disease." According to TCM, the pathophysiology of DR is primarily attributed...