Integrated Multi-Omics Analysis Identifies PDK4 and ACOT1 as Metabolic Hub Genes Associated With Myocardial Fibrosis in Diabetic Cardiomyopathy [0.03%]
整合多组学分析鉴定出PDK4和ACOT1是糖尿病心肌病心肌纤维化相关代谢关键基因
Huan Liu,Guanming Qi,Shengrong Ouyang et al.
Huan Liu et al.
Diabetic cardiomyopathy (DCM) is a critical pathological driver of heart failure in diabetic patients, primarily characterized by progressive myocardial fibrosis. Nevertheless, the core molecular network linking upstream metabolic dysregula...
Diabetic Atrial Cardiomyopathy: Pathogenesis, Diagnosis, Management, AI-Driven Diagnosis, and Risk Prediction [0.03%]
糖尿病性心房心肌病：发病机制、诊断、管理、人工智能驱动的诊断和风险预测
Helin Yang,Kexiao Yu,Bing Liang
Helin Yang
Background: Diabetic atrial cardiomyopathy, a component of diabetic cardiomyopathy, is increasingly recognized. However, atrial-focused mechanistic and clinical frameworks remain less developed than ventricular paradigms....
A Qualitative Exploration of the Support Needs of Individuals With Type 2 Diabetes and Disordered Eating Behaviours [0.03%]
2型糖尿病伴饮食紊乱患者的治疗需求探究
Emma Reid,Talitha Best,Alicia Carter et al.
Emma Reid et al.
Aims: We aim to explore the support needs of individuals living with type 2 diabetes and disordered eating behaviours. Methods: We cond...
Healing Outcomes in Diabetic Foot Ulcers Managed Within a Structured Multidisciplinary Care Model: A Retrospective Study [0.03%]
糖尿病足溃疡在结构化多学科护理模型下的治疗效果：一项回顾性研究
Gadadharan Vijayakumar,Jazeela Abdul Rahim,Gopika Satheesh et al.
Gadadharan Vijayakumar et al.
Background: Diabetic foot ulcers (DFU) impose a healthcare burden due to prolonged hospitalization, high amputation rates, and increased mortality. This study evaluated healing outcomes and explored factors associated wit...
CD36 Regulates PANoptosis in Diabetic Retinopathy via the NOTCH/MAML Pathway [0.03%]
糖尿病性视网膜病变中，CD36通过NOTCH/MAML通路调节PANoptosis现象
Rongfeng Dai,Yu Qian,Siqi Liu et al.
Rongfeng Dai et al.
Worldwide, diabetic retinopathy (DR) stands as a leading cause of vision loss. However, the involvement of PANoptosis-a form of inflammatory cell death that combines features of apoptosis, pyroptosis, and necroptosis-in the development of D...
Association of Serum Bilirubin Levels With Histopathological Severity of Diabetic Nephropathy in Patients With Type 2 Diabetes: A Cross-Sectional Biopsy Study [0.03%]
血清胆红素水平与2型糖尿病肾活检患者糖尿病肾病病理严重程度的相关性：横断面活检研究
Xiaorong Wang,Congqin Zhang,Chunxia Zhang et al.
Xiaorong Wang et al.
Background: Prior studies have suggested that serum total bilirubin (TBil) may be linked to diabetic nephropathy (DN); however, its potential relationship with structural renal injury in histopathology has not been well d...
Advances in the Identification of Novel Urinary Biomarkers for Diabetic Kidney Disease [0.03%]
糖尿病肾病新型尿液生物标志物的研究进展
Yujie Jin,Yan Ma,Yan Yao et al.
Yujie Jin et al.
Diabetic kidney disease (DKD) is a major microvascular complication of diabetes and remains one of the leading causes of end-stage renal disease, significantly affecting patients' survival rates and quality of life. Currently, commonly used...
Prehypertension, Hypertension, and Their Association With Weight-Adjusted Waist Index in Normoglycemic Japanese Adults: A Cross-Sectional Study [0.03%]
正常血糖日本成人前期高血压与高血压的腰围体重指数交叉-sectional研究
Jing Fan,Lu Wang,Fawang Li et al.
Jing Fan et al.
Objective: Obesity, impaired glucose tolerance, and diabetes significantly increase hypertension risk. Previous studies across various populations have linked the weight-adjusted waist index (WWI)-a key indicator for asse...
GDF15: A Novel Insight Into Its Biology and Therapeutic Potential in Obesity [0.03%]
肥胖症中GDF15生物学及其治疗潜能的新见解
Kamil Ahmed,Asia Saturnino,Paolo Pozzilli
Kamil Ahmed
Growth differentiation factor 15 (GDF15) is a stress-responsive cytokine that has recently been identified as a key regulator of appetite homeostasis. Although GDF15 was previously regarded as only a biomarker of disease burden, the discove...
Prediabetes Phenotypes and Adiposity Patterns: Findings From a Population-Based Study [0.03%]
中国一项基于人口的糖尿病前期表型和肥胖模式研究
Jincheng Rong,Mandy Ho,Sarah Garnett et al.
Jincheng Rong et al.
Background: Prediabetes is a heterogeneous condition encompassing three glucose-defined phenotypes (isolated impaired fasting glucose [i-IFG], isolated impaired glucose tolerance [i-IGT], and IFG + IGT), with distinct pat...