Prehypertension, Hypertension, and Their Association With Weight-Adjusted Waist Index in Normoglycemic Japanese Adults: A Cross-Sectional Study [0.03%]
正常血糖日本成人前期高血压与高血压的腰围体重指数交叉-sectional研究
Jing Fan,Lu Wang,Fawang Li et al.
Jing Fan et al.
Objective: Obesity, impaired glucose tolerance, and diabetes significantly increase hypertension risk. Previous studies across various populations have linked the weight-adjusted waist index (WWI)-a key indicator for asse...
GDF15: A Novel Insight Into Its Biology and Therapeutic Potential in Obesity [0.03%]
肥胖症中GDF15生物学及其治疗潜能的新见解
Kamil Ahmed,Asia Saturnino,Paolo Pozzilli
Kamil Ahmed
Growth differentiation factor 15 (GDF15) is a stress-responsive cytokine that has recently been identified as a key regulator of appetite homeostasis. Although GDF15 was previously regarded as only a biomarker of disease burden, the discove...
Prediabetes Phenotypes and Adiposity Patterns: Findings From a Population-Based Study [0.03%]
中国一项基于人口的糖尿病前期表型和肥胖模式研究
Jincheng Rong,Mandy Ho,Sarah Garnett et al.
Jincheng Rong et al.
Background: Prediabetes is a heterogeneous condition encompassing three glucose-defined phenotypes (isolated impaired fasting glucose [i-IFG], isolated impaired glucose tolerance [i-IGT], and IFG + IGT), with distinct pat...
Expression Signatures of Vascular Complication-Associated Proteins in Type 2 Diabetes: A Multiomics Analysis From the FIELD Study [0.03%]
糖尿病驱动的血管并发症相关蛋白表达标志物的多组学分析：FIELD研究结果
Habib Francis,Andrzej S Januszewski,Abubakar S Mangani et al.
Habib Francis et al.
Aims: The aim of the study is to integrate targeted transcriptomic analyses of previously identified biomarker proteins (proteomic findings) to better understand vascular complications (Cx) in Type 2 diabetes (T2D). ...
Selection and Validation of Novel Biomarkers for ntOPN-Based Models for Diabetic Kidney Disease in Patients With Diabetes Mellitus [0.03%]
糖尿病患者用于诊断糖尿病肾脏疾病的基于ntOPN模型的新型生物标志物的选择与验证
Lu-Xi Zou,Zhi-Li Hou,Chen-Huan Qian et al.
Lu-Xi Zou et al.
Introduction: We previously found that urinary n-terminal osteopontin (ntOPN) performed well for predicting diabetic kidney disease (DKD). This study is aimed at screening potential biomarkers for improving ntOPN-based mo...
Evaluation of the Risk Prediction Model for Frailty in Diabetic Patients: A Systematic Review and Meta-Analysis [0.03%]
糖尿病患者衰弱风险预测模型的评价：系统评价和 meta 分析
Qing Chen,Meiling Yang,Mengmeng Chen et al.
Qing Chen et al.
Background: Frailty is highly prevalent among patients with diabetes and is associated with an increased risk of disability, hospitalization, and mortality. Although several frailty prediction models have been developed f...
Implementing Patient Decision Aids for Insulin Initiation in China: What are the Barriers and Facilitators? A TDF-Based Qualitative Study [0.03%]
基于TDF的质性研究：在中国实施胰岛素启动患者决策辅助工具会遇到哪些障碍和促进因素？
Dan Yang,Hongzhan Jiang,Meiqi Meng et al.
Dan Yang et al.
Background: When oral antidiabetic drugs are insufficient to achieve glycemic control in Type 2 diabetes mellitus (T2DM), patients face the decision of whether to initiate insulin therapy. Patient decision aids (PtDAs) fa...
Long-Term Health Outcomes in Individuals With Confirmed Versus Unconfirmed Undiagnosed Diabetes Based on Oral Glucose Tolerance Test: Findings From the Tehran Lipid and Glucose Study [0.03%]
基于口服葡萄糖耐量试验确诊与未确诊糖尿病个体的长期健康结局：德黑兰血脂和血糖研究的结果
Navid Ebrahimi,Samaneh Asgari,Maryam Tohidi et al.
Navid Ebrahimi et al.
Background: To evaluate the prognostic performance of the single-sample confirmatory definition of undiagnosed diabetes on outcomes, including hypertension, chronic kidney disease (CKD), cardiovascular disease (CVD), and ...
Complement System-Related Genes in Diabetic Nephropathy: Screening for Potential Targets of the Mechanism [0.03%]
糖尿病肾病中补体系统相关基因的筛选及机制作用研究
Lifang Wei,Ye Li,Yuhui Lu et al.
Lifang Wei et al.
Diabetic nephropathy (DN) is the most common complication of diabetes, with immune-mediated inflammation playing a significant role in its pathophysiology. The complement system, a key proinflammatory factor, is implicated in DN. This study...
Multiomics Mendelian Randomization Identifies Lactylation-Related Molecular Traits in Type 1 Diabetes [0.03%]
多组学孟德尔随机化识别出1型糖尿病相关的乳酰化相关分子特征
Yu Ding,Shiyang Gao,Lingwen Ying et al.
Yu Ding et al.
Background: Lactylation is a posttranslational modification involved in cellular metabolic and immune processes. Although dysregulated lactate metabolism has been implicated in type 1 diabetes (T1D), the genetic relevance...