Recent advances and novel agents for FLT3 mutated acute myeloid leukemia [0.03%]
急性髓系白血病FLT3突变的最新进展和新型药物治疗
Rahul Pawar,Omar Preet Singh Bali,Bharat Kumar Malhotra et al.
Rahul Pawar et al.
Acute myeloid leukemia (AML) is a devastating hematologic malignancy that affects both older adults as well as children. Treatments available for AML largely depend on cytotoxic agents and often the only curative option is an allogeneic bon...
Cutaneous metastasis as an initial presentation of lung adenocarcinoma with KRAS mutation: a case report and literature review [0.03%]
带有KRAS突变的肺腺癌皮肤转移作为初始表现一例及相关文献复习
Huijuan Liao,Shenhong Wu,Stephen R Karbowitz et al.
Huijuan Liao et al.
Cutaneous metastasis as an initial presentation occurs in 0.8% of patients with internal malignancies, and is poorly understood in its molecular pathogenesis. We reported a case in which a 61-year-old male patient initially presented with r...
Bin Kang,Xiao-Hong Sun
Bin Kang
Like normal stem cells, cancer stem cells (CSCs) are capable of self-renewal, either by symmetric or asymmetric cell division. They have the exclusive ability to reproduce malignant tumors indefinitely, and to confer resistance in response ...
Isolated factor V deficiency in a patient with elevated PT and aPTT during routine pre-operative laboratory screening [0.03%]
术前常规实验室筛查中发现的因子V缺乏症并发PT和APTT延长的病例报告
Keyur Thakar,Kaushal Parikh,Yamei Chen et al.
Keyur Thakar et al.
Isolated factor V (FV) deficiency is a rare disorder with approximately 150 cases reported in the literature since 1943. Bleeding symptoms from FV deficiency vary widely. FV deficiency usually manifests early in the life. We present a 59-ye...
Protein kinase C delta (PKCδ) splice variant modulates senescence via hTERT in adipose-derived stem cells [0.03%]
蛋白激酶Cδ(PKCδ)剪切变体通过hTERT调节脂肪来源干细胞的衰老过程
Gay Carter,Rekha Patel,André Apostolatos et al.
Gay Carter et al.
Background: Adipose-derived stem cells (ADSC) were isolated and characterized from lean and obese subjects. We previously reported that distinct differences were observed in differentiating lean and obese preadipocytes. P...
A new Stem Cell Investigation [0.03%]
新的干细胞研究
Zhizhuang Joe Zhao,Delong Liu
Zhizhuang Joe Zhao
Andreas Kurtz,Su-Jun Oh
Andreas Kurtz
Caleb E Finch,Andrew P McMahon
Caleb E Finch
Megakaryocytes regulate the quiescence of hematopoietic stem cells through PF4: 2013 ASH meeting highlights [0.03%]
巨大血小板系细胞通过PF4调节造血干细胞的静息状态：2013ASH年会亮点报告
Yamei Chen,Delong Liu
Yamei Chen
Hematopoietic stem cells (HSCs) can take one of the three different pathways: quiescence, self-renewal and differentiation. Mechanisms that control the tight balance to maintain lifelong hematopoietic homeostasis have been a major interest ...