Interplay between BMP2 and Notch signaling in endothelial-mesenchymal transition: implications for cardiac fibrosis [0.03%]
骨形态发生蛋白2与 notch 信号通路在内皮-间质转化中的交互作用及其对心脏纤维化的影响
Pavel Docshin,Ahmad Bairqdar,Anna Malashicheva
Pavel Docshin
Background: The endothelial-to-mesenchymal transition (EndoMT) is a crucial process in cardiovascular development and disorders. Cardiac fibrosis, characterized by excessive collagen deposition, occurs in heart failure, l...
Primary central nervous system lymphoma: treatment access and outcomes in HIV positive patients in a minority rich cohort [0.03%]
HIV阳性患者中枢神经系统淋巴瘤的治疗及其疗效——以少数族裔占多数的一组人群为例
Hiba Narvel,Charan Vegivinti,Sindhu Vikash et al.
Hiba Narvel et al.
Novel Human Umbilical Di-Chimeric (HUDC) cell therapy for transplantation without life-long immunosuppression [0.03%]
一种新颖的用于无需终生免疫抑制的人类脐带二嵌合体(HUDC)细胞疗法
Maria Siemionow,Joanna Cwykiel,Lucile Chambily et al.
Maria Siemionow et al.
Background: Cell-based therapies are promising for tolerance induction in bone marrow (BM), solid organs, and vascularized composite allotransplantation (VCA). The toxicity of bone marrow transplantation (BMT) protocols p...
The quest for the holy grail: overcoming challenges in expanding human hematopoietic stem cells for clinical use [0.03%]
追寻圣杯:临床扩增人源造血干细胞的机遇与挑战
Sepideh Bastani,Frank J T Staal,Kirsten Canté-Barrett
Sepideh Bastani
Hematopoietic stem cell (HSC) transplantation has been the golden standard for many hematological disorders. However, the number of HSCs obtained from several sources, including umbilical cord blood (UCB), often is insufficient for transpla...
Identification and characterization of enhancer elements controlling cell type-specific and signalling dependent chromatin programming during hematopoietic development [0.03%]
识别和表征造血发育过程中控制细胞类型特异性及信号依赖性染色质编程的增强子元件
Alexander Maytum,Ben Edginton-White,Constanze Bonifer
Alexander Maytum
The development of multi-cellular organisms from a single fertilized egg requires to differentially execute the information encoded in our DNA. This complex process is regulated by the interplay of transcription factors with a chromatin env...
Immunophenotypic analysis of human adipose-derived stem cells through multi-color flow cytometry [0.03%]
人脂肪来源干细胞的流式细胞术多色免疫表型分析
Paolo Giuseppe Limoli,Marcella Nebbioso
Paolo Giuseppe Limoli
Femur bone marrow from brain death deceased donors as source of human mesenchymal stromal cells for cell therapy [0.03%]
脑死亡捐献者股骨骨髓间充质基质细胞作为细胞治疗的种子细胞来源
Lourdes Echarte,Alexandra Sujanov,Daniel Machin et al.
Lourdes Echarte et al.
Background: The use of a deceased donor (DD) as an alternative source of human mesenchymal stromal cells (hMSC) is promising, but has been little explored. This study evaluated the potential of femur bone marrow (FBM) fro...
Malignant clonal evolution from high proportion of monocytes in patients with aplastic anemia: a case report [0.03%]
纯红细胞再生障碍性贫血合并急性髓系白血病1例报告
Qiuhao Fu,Lingling Liu,Yingmei Li
Qiuhao Fu
Background: Aplastic anemia (AA) is a heterogeneous group of hematopoietic failure diseases, characterized mainly by immune hyperfunction, impaired immune tolerance, the hematopoietic microenvironment, and hematopoietic s...
Case Reports
Stem cell investigation. 2023 May 15:10:11. DOI:10.21037/sci-2022-049 2023
Transcriptomic analysis of feeder-free culture system for maintaining naïve-state pluripotency in human pluripotent stem cells [0.03%]
无饲养层培养体系维持人多能干细胞初始态的转录组分析研究
Wataru Isono,Tomoyuki Kawasaki,Justin K Ichida et al.
Wataru Isono et al.
Background: Human pluripotent stem cells (hPSCs) such as embryonic stem cells (ESCs) and induced pluripotent stem cells (PSCs) have the capacity of self-renewal and multilineage differentiation in vitro. Conventional hPSC...
Macrophages and stem/progenitor cells interplay in adipose tissue and skeletal muscle: a review [0.03%]
巨噬细胞与干细胞/前体细胞在脂肪组织和骨骼肌中的相互作用:综述
Malgorzata Kloc,Ahmed Uosef,Henry V Ubelaker et al.
Malgorzata Kloc et al.
Like all immune cells, macrophages do not act autonomously but in unison with other immune cells, surrounding tissues, and the niche they occupy. Constant exchange of information between cellular and noncellular participants within a tissue...