TP63 drives TKI resistance in EGFR-mutant lung cancer via ferroptosis inhibition [0.03%]
TP63通过抑制铁死亡诱导EGFR突变型肺癌对TKI产生耐药性
Kehan Li,Jiane Liu,Wenjuan Wang et al.
Kehan Li et al.
Background: The emergence of acquired resistance to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) presents a significant obstacle in the therapeutic strategy for EGFR-mutant non-small cell lung...
Short- and long-term outcomes after laparoscopic versus open total gastrectomy for stage 0-I gastric cancer: a multicenter, retrospective analysis [0.03%]
腹腔镜全胃切除术与开腹全胃切除术治疗I期胃癌的短期和长期结局：一项多中心回顾性分析
Fangyao Zhou,Zaisheng Ye,Chengbin Zheng et al.
Fangyao Zhou et al.
Background: Laparoscopic surgery has been increasingly adopted in the treatment of gastric cancer. Although the safety and efficacy of laparoscopic distal gastrectomy have been well established, evidence regarding laparos...
Causal relationship between renin-angiotensin system inhibitors and cancer: a two-sample, two-step Mendelian randomization study [0.03%]
血管紧张素系统抑制剂和癌症之间的因果关系：两种工具的双样本两步孟德尔随机化研究
Chenggong Zeng,Juanhua Zhu,Xi Zhen et al.
Chenggong Zeng et al.
Background: The renin-angiotensin system (RAS), particularly the angiotensin II (AT2)/angiotensin I receptor axis, is implicated in promoting tumorigenesis. However, the causal relationship between angiotensin-converting ...
Development and validation of a diagnostic model based on artificial intelligence for diagnosing pancreatic cancer [0.03%]
基于人工智能的胰腺癌诊断模型的建立及验证
Fedor N Paramzin,Victor V Kakotkin,Dmitry A Burkin et al.
Fedor N Paramzin et al.
Background: The global incidence and mortality rates of pancreatic cancer have been on the rise in recent decades. At the same time, pancreatic cancer occupies a leading position among malignant neoplasms, which are often...
Davide Campobasso,Stefano Puliatti,Stefania Ferretti
Davide Campobasso
Bispecific immune-angiogenic blockade in extensive-stage small-cell lung cancer-positioning ivonescimab [0.03%]
广泛期小细胞肺癌中的双特异性免疫抗血管生成阻断治疗-ivonescimab的定位研究
Èlia Sais Girona,Joaquim Bosch-Barrera
Èlia Sais Girona
Cadonilimab plus chemotherapy in recurrent or metastatic nasopharyngeal carcinoma: a step forward for bispecific immunotherapy? [0.03%]
卡哆尼利联合化疗治疗复发或转移性鼻咽癌：双特异性免疫疗法的前进步伐？
Jia Li Low,Lu Lu Huang,Boon Cher Goh
Jia Li Low
Endocrine therapy in estrogen receptor-low breast cancer: new evidence, persistent questions [0.03%]
低雌激素受体乳腺癌的内分泌治疗：新证据与未决问题
Tomás Reinert,Maiane Maria Pauletto,Flavio Vinicius Costa Ferreira et al.
Tomás Reinert et al.
Preventing unplanned "whoops" sarcoma surgery: from technical pearls to early referral and network-level quality metrics [0.03%]
预防意外的副肿瘤肉瘤手术：从技术细节到早期转诊和网络层面的质量评估指标
Bruno Fuchs,Georg Schelling,Ruben Jaeger
Bruno Fuchs