Diurnal variation in clock gene expression and progesterone secretion is inhibited under constant light conditions in Japanese Black cows [0.03%]
日本黑牛在恒定光照条件下时钟基因表达和孕酮分泌的昼夜节律被抑制
Tsuyoshi Otsuka,Hiroki Mitsuishi,Hiroki Onishi et al.
Tsuyoshi Otsuka et al.
The circadian clock is constructed by a transcription-translation feedback loop system of clock genes and regulates various reproductive physiological functions. Understanding the rhythms of clock gene expression is important for understand...
Bovine ampullary and isthmic epithelial spheroids: proteomic profile and physiological features for in vitro studies of gamete-oviduct interactions [0.03%]
牛输卵管壶腹部和峡部上皮球体的生理特征及蛋白质组分析：体外配子输卵管上皮相互作用研究
Coline Mahé,Ludivine Marco,Ludivine Laffont et al.
Coline Mahé et al.
After mating or insemination, spermatozoa reach the first part of the oviduct, known as the isthmus, where a subpopulation binds to the epithelial cilia, forming a reservoir. Then, spermatozoa migrate toward the ampulla, where additional in...
Protective role of gallic acid in sperm health and environmentally induced male infertility: A narrative review of human-relevant and translational preclinical studies [0.03%]
没食子酸在精子健康和环境因素诱导的男性不育中的保护作用：基于具有人类相关性和转化预临床研究的叙述性综述
Weitian Chen,Junfeng Qiu,Zhiming Hong et al.
Weitian Chen et al.
Male infertility has become a growing global concern due to the decline in sperm quality, largely influenced by environmental toxins, aging, and lifestyle factors. This comprehensive review investigates the potential protective effects of g...
Surgical management of ovarian torsion in children: Detorsion, cyst/mass excision, and ovarian fixation [0.03%]
儿童卵巢扭转的手术治疗：复位、囊/肿切除和卵巢固定术
Serpil Sancar,Meryem Anayurt,Sabriye Dayı
Serpil Sancar
This study evaluated surgical interventions based on the presence or absence of ovarian cysts or masses in pediatric and adolescent patients with ovarian torsion (OT) and analyzed their impact on retorsion development. A retrospective revie...
The impact of dexamethasone on cellular stress responses caused by mild serum deprivation in androgen-insensitive prostate cancer cells [0.03%]
地塞米松对轻度血清剥夺诱导的雄激素不敏感前列腺癌细胞内质网应激反应的影响研究
Weronika Broszkiewicz,Jakub Beda,Kamila Domińska
Weronika Broszkiewicz
Dexamethasone (DEX), a glucocorticoid receptor agonist, is widely used for prostate cancer therapies, although its exact impact on androgen-independent prostate cancer cells remains unclear. As solid cancers are typically characterized by n...
Comparative study of sperm protamine gene expression and chromatin integrity in Nellore and Angus bulls [0.03%]
Nelore和Angus公牛精液protamine基因表达及染色质完整性的比较研究
Carlos Alonso Paco Nagaki,Thais Rose Dos Santos Hamilton,Camilla Mota Mendes et al.
Carlos Alonso Paco Nagaki et al.
Methodologies used to evaluate bull fertility often overlook sperm chromatin, a nuclear structure critical for reproductive success due to its DNA composition, which is tightly bound to nucleoproteins called protamines. In mammals, the rati...
Cryptorchidism-induced disruption of TRPM8 expression and calcium signaling in canine testes: A potential mechanism for tumourigenesis [0.03%]
隐睾导致犬睾丸中TRPM8表达及钙信号紊乱：一种潜在的致瘤机制
Anna Gałuszka,Wojciech Łopuszyński,Patrycja Kurowska et al.
Anna Gałuszka et al.
Cryptorchidism is a condition where one or both testes fail to descend, increasing the risk of tumour development. This study investigated histological and molecular changes in canine cryptorchid testes, focusing on the TRPM8 calcium channe...
Use of an exogenous DNA-free system to generate MSTN-KO calves by CRISPR/Cas9 and SCNT [0.03%]
利用CRISPR/Cas9和体细胞核移植技术构建无外源DNA整合的MSTN基因敲除牛体系
Mariana Suvá,Juan Ignacio Bastón,Elisabet Astrid Wiedenmann et al.
Mariana Suvá et al.
This study aimed to obtain myostatin (MSTN)-knockout calves, while avoiding the risk of exogenous DNA integration during gene editing. To achieve this, we combined CRISPR/Cas9 ribonucleoprotein gene editing with somatic cell nuclear transfe...
Ewelina Trela-Kobędza,Anna Ajduk
Ewelina Trela-Kobędza
The number of pollutants stemming from anthropogenic chemicals is increasing every year. Some of them act similarly to hormones and are referred to as endocrine-disrupting chemicals or endocrine disruptors. In this group, bisphenol A (BPA) ...
Evaluation of the relative gene expression of FGF2, HAS2, BCL2, VEGFA, and PGR in repeat-breeder cows undergoing cyclicity or acyclicity [0.03%]
用于评估周期性和非周期性再生母牛中FGF2、HAS2、BCL2、VEGFA和PGR基因表达相对水平的分析方法
Punnawut Yama,Napatsorn Montha,Jakree Jitjumnong et al.
Punnawut Yama et al.
Repeat breeder syndrome (RBS) is one of the main reproductive failures in mono-ovulatory dairy cattle. The differential relative expression of several important genes in the ovary and uterus were evaluated in repeat-breeder dairy cattle. Co...