The mouse model of induced sperm DNA damage caused by polystyrene microplastics exhibited distinct transcriptomic and proteomic features [0.03%]
聚苯乙烯微塑料诱导小鼠精子DNA损伤的基因表达和蛋白变化特征研究
Chenming Zhang,Xiaofei Han,Yifei Wang et al.
Chenming Zhang et al.
Polystyrene microplastics (PS-MPs) are extensively utilized in plastic goods worldwide. The ingestion of PS-MPs has resulted in a high rate of DNA fragmentation index (DFI), which can potentially result in infertility and recurrent spontane...
Phloretin enhances the efficiency of sheep oocyte IVM and early embryonic development by bolstering antioxidant defenses, inhibiting apoptosis, and promoting development [0.03%]
茋通过增强抗氧化防御、抑制凋亡和促进发育来提高羊卵母细胞体外成熟和早期胚胎发育的效率
Xu Li,Shuhong Tang,Yinwei Zheng et al.
Xu Li et al.
Phloretin, a natural dihydrochalcone flavonoid, is recognized for its potent antioxidant, anti-apoptotic, and anti-inflammatory properties. This study investigated the effects of phloretin on the in vitro maturation (IVM) of sheep oocytes a...
Annatto concentrate supplementation improves systemic redox balance and modulates placental FGF-2 expression in ewes [0.03%]
红树胶浓缩物补充改善母羊的全身氧化还原平衡并调节胎盘FGF-2表达
Leonardo Lima Salata,Calie Castilho,Isabella Guartieri da Silva et al.
Leonardo Lima Salata et al.
Annatto (Bixa orellana) carotenoids have antioxidant potential, but effects on placental biology and antioxidant parameters in ewes are unclear. We tested whether dietary annatto concentrate (ANC) in late gestation modulates immediate-postp...
Emerging role and interplay of programmed cell death in endometritis: Insights into mechanisms and therapeutic targets [0.03%]
子宫内膜炎中程序性细胞死亡的作用及相互作用：机制和治疗靶点的启示
Islam Ahmed Abdelmawgood,Dina M M Kotb,Ahmed Ezzat Mostafa et al.
Islam Ahmed Abdelmawgood et al.
Endometritis is the inflammation of the endometrial lining, frequently linked to pelvic pain. Endometritis is significantly associated with postpartum problems, including infertility. Programmed cell death (PCD) is a genetically regulated m...
Non-surgical sterilization of male animals using sclerosing agents: A systematic review of intratesticular and intraepididymal injection protocols [0.03%]
使用硬化剂进行雄性动物非手术去势的系统评价：睾丸和附睾内注射方案
Iara Magalhães Ribeiro,Renner Philipe Rodrigues Carvalho,Arabela Guedes de Azevedo Viana et al.
Iara Magalhães Ribeiro et al.
The overpopulation of free-roaming animals, particularly dogs and cats, poses a significant global public health concern, contributing to socioeconomic, ecological, political, and ethical issues. These animals reproduce freely, increasing t...
USP13 exacerbates the malignant progression of cervical cancer by inhibiting ECT2 ubiquitination and degradation [0.03%]
USP13通过抑制ECT2泛素化及降解促进宫颈癌恶性进展
Tingting Li,Xiulan Xiong,Tingting Xie et al.
Tingting Li et al.
Cervical cancer (CC) is one of the most common malignant tumors affecting the female reproductive system. Epithelial Cell Transforming Sequence 2 (ECT2), a guanine nucleotide exchange factor, is crucial in regulating cellular functions. Thi...
Influence of different cell passage numbers on bovine cloned embryo: A systematic review and meta-analysis [0.03%]
不同传代数的体细胞对牛克隆胚胎影响的系统评价和meta分析
Haris Setiawan,Agung Irawan
Haris Setiawan
Animal cloning remains inefficient, with live birth rates below 5 % in most mammalian species, slightly higher in bovines (20-25 %). Among various factors, nuclear donor cells play crucial roles, and their passage numbers may influence clon...
Branched chain amino acid sufficiency is necessary for proper luteinizing hormone response and testosterone synthesis [0.03%]
支链氨基酸的充足性对于适当的黄体生成素反应和睾酮合成是必要的
Yeva Shamailova,Saad A Farooq,Megan E Gilmore et al.
Yeva Shamailova et al.
Testosterone production by testicular Leydig cells (steroidogenesis) is vital to male fertility and overall male health. Information about how nutrition influences Leydig cell steroidogenesis is lacking. Branched chain amino acids (BCAAs - ...
Extracellular vesicles derived from placental trophoblast regulate ovine endometrial receptivity by promoting the transformation of endometrial epithelial cells [0.03%]
来源于胎盘滋养细胞的外泌体通过促进子宫内膜上皮细胞转化调节羊子宫内膜容受性
Huijia Jin,Yujiao Guo,Yanshe Xie et al.
Huijia Jin et al.
The establishment of endometrial receptivity is required for successful embryo implantation during early pregnancy in many mammals. Extracellular vesicles (EVs) microRNAs (miRNAs) play an important role during embryo implantation. While the...
Cytotoxicity, antioxidant activity, and gene expression effects of gossypol in primary smooth muscle of myometrium from Ovis aries (PSMo24) cells [0.03%]
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Carolina Rodriguez Jimenez,Bruno Scatena Gatti,Daniela Pimenta et al.
Carolina Rodriguez Jimenez et al.
This study aimed to investigate the effects of gossypol on cell viability, oxidative stress, and gene expression in Primary Smooth Muscle of Myometrium from Ovis aries (PSMo24) Cells. The cells were cultured and treated with varying concent...