Oocyte-intrinsic aging drives whole-chromosome aneuploidy independent of ovarian reserve beyond maternal age as risk factor [0.03%]
卵母细胞内在老化独立于卵巢储备驱动整倍体非整倍性变化而非高龄产妇的风险因素
Pham Thi Hai Ha,Mai Vuong Hung,Nguyen Khac Han Hoan et al.
Pham Thi Hai Ha et al.
This retrospective cross-sectional study investigated whether maternal age functions as an independent risk factor for chromosomal aneuploidy in day-5 blastocysts through oocyte-intrinsic aging mechanisms rather than quantitative ovarian re...
Integrative assessment of gamete and embryo quality in porcine in vitro production: A comprehensive review [0.03%]
猪体外受精综合评估：全面综述
Victoria Slezec-Frick,Guillaume Lenoir,Loris Commin et al.
Victoria Slezec-Frick et al.
Despite significant progress in porcine in vitro embryo production (IVP), major challenges persist, particularly regarding the biological quality and developmental competence of gametes and embryos produced in vitro. The lack of standardise...
Patterns of cell exclusion in human embryos reveal a stage-dependent association with the detection of fetal heartbeat within fresh cycles [0.03%]
人类胚胎的细胞排除模式揭示了与新鲜周期中胎儿心跳检测的阶段依赖性联系
Radhika Kakulavarapu,Aleksej Stevanovic,Mario Iliceto et al.
Radhika Kakulavarapu et al.
Cell exclusion (CE) is a morphological phenomenon observed and characterized relative to embryo morulation, yet its implications for reproductive competence seem heterogeneous. This study investigated whether variability in reproductive suc...
Temporal characterization of conditions that promote functional capacitation of stallion sperm [0.03%]
促进公马精子功能获能的条件的时间特征分析
Joao D de Agostini Losano,Jillian E Guertin,Maura S McGraw et al.
Joao D de Agostini Losano et al.
Equine in vitro fertilization (IVF) has historically been challenged due to lack of conditions that promote functional capacitation of stallion sperm. Capacitation success is often attributed to prolonged sperm incubation requirements. Adva...
From food to infertility: Disruption of the male reproductive axis by wheat lectin in rats [0.03%]
从食物到不育：麦属凝集素通过干扰大鼠的雄性生殖轴作用而导致不育的研究
Ini-Ibehe E Okoko,Bamidele A Iwalokun,Francis I O Duru et al.
Ini-Ibehe E Okoko et al.
Male fertility is declining globally, prompting efforts to identify contributing dietary factors. Wheat, a major staple worldwide, provides caloric and protein value but also contains anti-nutritional components such as wheat germ agglutini...
Amygdalin inhibits 17β-estradiol-induced mesenchymal transition through TGF- β/Smad signaling in normal and endometriotic endometrial epithelial cells [0.03%]
苦杏仁苷通过TGF-β/Smads信号通路抑制雌二醇诱导的内膜细胞上皮间质转化的作用及机制研究
Fang Hu,Jie Zheng,Guoqiong Zhang et al.
Fang Hu et al.
Endometriosis is a common gynecological disorder characterized by chronic pelvic pain, infertility, and systemic symptoms, with currently limited treatment options. Amygdalin, a cyanogenic glycoside derived from bitter apricot kernels, has ...
HDAC2 regulates oocyte maturation in Tan sheep via its strong association with regulating H4K12 acetylation and EREG secretion [0.03%]
HDAC2通过强烈调节H4K12乙酰化和EREG分泌来调节滩羊卵母细胞成熟
Junli He,Yaxiu Xu,Xiangyan Wang et al.
Junli He et al.
This study aimed to explore the potential mechanism of histone deacetylase 2 (HDAC2) in follicular development and oocyte maturation of Tan sheep, and clarify whether it affects oocyte maturation by responding to luteinizing hormone (LH) si...
Adipogenesis and myogenesis transcriptome in Piau local breed conceptuses and its comparison with Commercial pig data [0.03%]
皮豪猪地方品种胚胎的脂肪发生和肌细胞发生的转录组及其与商业品种数据对比研究
Tânia Fernandes Martins,Susana Amaral Teixeira,Lucas Lima Verardo et al.
Tânia Fernandes Martins et al.
The growth and development of skeletal muscle, along with intramuscular fat deposition, determine the quantity and quality of pork. The Brazilian Piau breed, which has not undergone genetic improvement, exhibits slower growth, greater fat d...
Chronic ozone exposure does not alter sexual behavior but modulates oxidative stress and early testicular apoptosis in adult male rats [0.03%]
慢性臭氧暴露不影响雄性大鼠的性行为，但可调节氧化应激和生精小管早期凋亡现象
Ahmet Yardimci,Nazife Ulker Ertugrul,Ramazan Fazil Akkoc et al.
Ahmet Yardimci et al.
Ozone (O₃) has been used to treat various diseases for many years, with most preclinical studies focusing on its effects in conditions such as testicular torsion and ischemia-reperfusion injury; however, its impact on male reproductive fun...
Metabolic-endocrine remodelling of the testis under polystyrene nanoplastic exposure: Intervention by organ-specific phytocomplexes of Nelumbo nucifera [0.03%]
聚苯乙烯纳米塑料暴露下荷花器官特异性植物复合物对睾丸代谢-内分泌重塑的干预作用
Putri Ayu Ika Setiyowati,Febriyansyah Saputra,Firli Rahmah Primula Dewi et al.
Putri Ayu Ika Setiyowati et al.
Polystyrene nanoplastics (PS-NPs) are emerging endocrine-disrupting pollutants that can accumulate systemically and impair male reproduction by inducing oxidative stress, hormonal dysregulation, and disrupted spermatogenesis. Nelumbo nucife...