From food to infertility: Disruption of the male reproductive axis by wheat lectin in rats [0.03%]
从食物到不育：麦属凝集素通过干扰大鼠的雄性生殖轴作用而导致不育的研究
Ini-Ibehe E Okoko,Bamidele A Iwalokun,Francis I O Duru et al.
Ini-Ibehe E Okoko et al.
Male fertility is declining globally, prompting efforts to identify contributing dietary factors. Wheat, a major staple worldwide, provides caloric and protein value but also contains anti-nutritional components such as wheat germ agglutini...
Amygdalin inhibits 17β-estradiol-induced mesenchymal transition through TGF- β/Smad signaling in normal and endometriotic endometrial epithelial cells [0.03%]
苦杏仁苷通过TGF-β/Smads信号通路抑制雌二醇诱导的内膜细胞上皮间质转化的作用及机制研究
Fang Hu,Jie Zheng,Guoqiong Zhang et al.
Fang Hu et al.
Endometriosis is a common gynecological disorder characterized by chronic pelvic pain, infertility, and systemic symptoms, with currently limited treatment options. Amygdalin, a cyanogenic glycoside derived from bitter apricot kernels, has ...
HDAC2 regulates oocyte maturation in Tan sheep via its strong association with regulating H4K12 acetylation and EREG secretion [0.03%]
HDAC2通过强烈调节H4K12乙酰化和EREG分泌来调节滩羊卵母细胞成熟
Junli He,Yaxiu Xu,Xiangyan Wang et al.
Junli He et al.
This study aimed to explore the potential mechanism of histone deacetylase 2 (HDAC2) in follicular development and oocyte maturation of Tan sheep, and clarify whether it affects oocyte maturation by responding to luteinizing hormone (LH) si...
Adipogenesis and myogenesis transcriptome in Piau local breed conceptuses and its comparison with Commercial pig data [0.03%]
皮豪猪地方品种胚胎的脂肪发生和肌细胞发生的转录组及其与商业品种数据对比研究
Tânia Fernandes Martins,Susana Amaral Teixeira,Lucas Lima Verardo et al.
Tânia Fernandes Martins et al.
The growth and development of skeletal muscle, along with intramuscular fat deposition, determine the quantity and quality of pork. The Brazilian Piau breed, which has not undergone genetic improvement, exhibits slower growth, greater fat d...
Chronic ozone exposure does not alter sexual behavior but modulates oxidative stress and early testicular apoptosis in adult male rats [0.03%]
慢性臭氧暴露不影响雄性大鼠的性行为，但可调节氧化应激和生精小管早期凋亡现象
Ahmet Yardimci,Nazife Ulker Ertugrul,Ramazan Fazil Akkoc et al.
Ahmet Yardimci et al.
Ozone (O₃) has been used to treat various diseases for many years, with most preclinical studies focusing on its effects in conditions such as testicular torsion and ischemia-reperfusion injury; however, its impact on male reproductive fun...
Metabolic-endocrine remodelling of the testis under polystyrene nanoplastic exposure: Intervention by organ-specific phytocomplexes of Nelumbo nucifera [0.03%]
聚苯乙烯纳米塑料暴露下荷花器官特异性植物复合物对睾丸代谢-内分泌重塑的干预作用
Putri Ayu Ika Setiyowati,Febriyansyah Saputra,Firli Rahmah Primula Dewi et al.
Putri Ayu Ika Setiyowati et al.
Polystyrene nanoplastics (PS-NPs) are emerging endocrine-disrupting pollutants that can accumulate systemically and impair male reproduction by inducing oxidative stress, hormonal dysregulation, and disrupted spermatogenesis. Nelumbo nucife...
Investigating trophoblast invasion and angiogenesis expression changes in a caloric deficient mouse model of fetal growth restriction [0.03%]
营养缺乏的小鼠胎儿生长受限模型中滋养细胞侵袭和血管生成表达变化的研究
James R Bardill,Caitlin R Eason,Holly Wood et al.
James R Bardill et al.
Fetal growth restriction (FGR) is a severe pregnancy complication often caused by placental insufficiency. Proper trophoblast invasion is essential for placental development and function, ensuring adequate nutrient and oxygen supply to the ...
Hexavalent chromium inhibits testosterone synthesis in bovine testicular leydig cells through mitochondrial damage via BNIP3 [0.03%]
六价铬通过BNIP3介导的线粒体损伤抑制牛睾丸 Leydig细胞合成睾酮
Hongxia Li,Jia Liu,Liwei Huang et al.
Hongxia Li et al.
This study investigated the molecular mechanisms underlying the inhibitory effects of hexavalent chromium (Cr(Ⅵ)) exposure on testosterone synthesis in bovine testicular Leydig cells. First, bovine Leydig cells were isolated and purified, ...
L-carnitine or melatonin supplementation during vitrification and warming mitigates oxidative stress and improves cryotolerance in immature bovine cumulus-oocyte complexes [0.03%]
左卡尼汀或褪黑素在卵母细胞玻璃化冷冻过程中的氧化应激缓解及 cryotolerance 改善作用研究
Vivian A P Alfradique,Thais de A Oliveira,Thamiris E C Silva et al.
Vivian A P Alfradique et al.
Vitrification of immature cumulus-oocyte complexes (COCs) is a valuable tool in assisted reproductive technologies, but it often induces oxidative stress, reduces viability, and compromises developmental potential. This study investigated t...
Decreased autophagic activity in spermatozoa from infertile men adversely affects early embryonic development [0.03%]
不育男性精子自噬活性降低不利于早期胚胎发育
Mehmet Alper Arslan,Aysın Pınar Türkmen,Ramazan Aşcı
Mehmet Alper Arslan
Oligoasthenoteratozoospermia (OAT) is a complex reproductive health problem characterized by impaired sperm parameters. Autophagy serves critical functions in diverse stages of male reproduction and has been shown to be functionally active ...