Béatrice Laupèze,Robbert van der Most,Giuseppe Del Giudice
Béatrice Laupèze
Vaccine development has traditionally been driven by the need to prevent high numbers of childhood deaths due to infectious disease. With few exceptions, vaccines for adults are the same as vaccines for infants, although it has long been ap...
Jacek M Witkowski,Anis Larbi,Aurélie Le Page et al.
Jacek M Witkowski et al.
Aging is associated with changes in the immune system. Both (innate and adaptive) arms of the immune system are involved. Natural killer (NK) cells are part of the innate immune system. They participate in host defense by eliminating cells ...
Martijn D B van de Garde,Mirjam J Knol,Nynke Y Rots et al.
Martijn D B van de Garde et al.
Determining the optimal vaccination strategy for the protection of the elderly population against pneumococcal disease remains a challenge. Older adults are, second to young infants, most susceptible to become colonized and invaded by Strep...
Glenn Choon Lim Wong,Marie Clare Strickland,Anis Larbi
Glenn Choon Lim Wong
T lymphocytes follow three main stages of differentiation during their lifetime history - memory generation, memory homeostasis, and immunosenescence. Current definitions of T cell immunosenescence now include distinct aspects of both T cel...
Birgit Weinberger
Birgit Weinberger
Emily L Goldberg,Albert C Shaw,Ruth R Montgomery
Emily L Goldberg
The collective loss of immune protection during aging leads to poor vaccine responses and an increased severity of infection for the elderly. Here, we review our current understanding of effects of aging on the cellular and molecular dysreg...
Ageism, Aging and HIV: Community Responses to Prevention, Treatment, Care and Support [0.03%]
老龄化与艾滋病：预防、治疗、护理和支持的社区回应
Rosanna F DeMarco,Mark Brennan-Ing,Courtenay Sprague et al.
Rosanna F DeMarco et al.
Ageism, in the form of prejudice, stereotyping, and discrimination targeting older adults, represents a barrier to addressing the graying of the HIV epidemic. There is widespread misperception on the part of older adults themselves, as well...
Jacqueline Shorthill,Rosanna F DeMarco
Jacqueline Shorthill
The connection between palliative care and HIV infection has deep and wide roots in the United States that go back to the time when many gay men in the early 1980s were dying from a disease we knew little about, and there was no way to help...
Lisa E Cox,Mark Brennan-Ing
Lisa E Cox
Older people living with HIV are increasingly requiring formal supportive community-based services. Supportive services are essential to medical care and treatment for older people living with HIV/AIDS. This chapter considers Andersen's beh...
Mental Health, Psychosocial Challenges and Resilience in Older Adults Living with HIV [0.03%]
老年人艾滋病患者的身心健康、心理社会挑战及应对能力
Perry N Halkitis,Kristen D Krause,Dorice L Vieira
Perry N Halkitis
In addition to physical health challenges, older people living with HIV/AIDS (PLWHA) experience mental health burdens and challenges to their social well-being that diminish their overall health. These health states are synergistic and are ...