Wolfgang Jilg
Wolfgang Jilg
People who travel to countries where they are at risk of contracting specific infections often need specific vaccines. To make correct recommendations in this respect several points have to be considered. The state of health of the traveler...
Comorbidities in the Elderly and Their Possible Influence on Vaccine Response [0.03%]
老年人合并症及其对疫苗反应的可能影响
Anja Kwetkat,Hans Jürgen Heppner
Anja Kwetkat
The following chapter is focused on the impact of comorbidities on the effectiveness of vaccination in older persons. Relevant comorbidities are cardiovascular diseases like hypertension, coronary artery disease or congestive heart failure,...
Christopher A Green,Simon B Drysdale,Andrew J Pollard et al.
Christopher A Green et al.
Respiratory syncytial virus (RSV) causes infection throughout life, with infants, adults who are severely immunocompromised, and the elderly at special risk of developing lower respiratory tract disease, hospitalisation, and death. The burd...
Daniela Frasca,Bonnie B Blomberg
Daniela Frasca
The increase in the prevalence of obesity represents a worldwide phenomenon which is associated with several chronic diseases. In this review, we summarize published data showing how obesity, alone or together with the metabolic syndrome, i...
Fiona Ecarnot,Stefania Maggi,Jean-Pierre Michel
Fiona Ecarnot
Vaccine-preventable diseases represent a considerable burden on world health, and can have long-lasting consequences in those infected, especially in older adults, who can suffer functional decline, disability, and death. Vaccine uptake acr...
Annaliesa S Anderson,Ingrid L Scully,Michael W Pride et al.
Annaliesa S Anderson et al.
Nosocomial infections represent a major global disease burden, and effective treatments are urgently needed, especially among older adult populations (≥65 years of age). With increasing age, risk factors for these infections increase due t...
Robert W Johnson,Myron J Levin
Robert W Johnson
Herpes zoster (HZ; shingles) results from reactivation of varicella-zoster virus (VZV) after primary infection as varicella (chicken pox). It affects mainly older adults and people with immunocompromising diseases or treatments. The most co...
Influenza Vaccination: Accelerating the Process for New Vaccine Development in Older Adults [0.03%]
流感疫苗接种：加快老年人新疫苗开发进程
Janet E McElhaney,Melissa K Andrew,Laura Haynes et al.
Janet E McElhaney et al.
Increased susceptibility to the serious complications of influenza is common in older adults. It is often ascribed to weakening of the immune system with age, and 90% of influenza-related deaths occur in older adults despite widespread vacc...
Deborah K Dunn-Walters,Alexander T Stewart,Emma L Sinclair et al.
Deborah K Dunn-Walters et al.
Older people have reduced immune responses to infection and vaccination. B cell activation is key for the efficacy of the vaccine response, but there are several age-related changes in B cells which may contribute to the loss of vaccine eff...
Vaccination of Adults and the Older Population against Tetanus, Diphtheria, Pertussis, and Tick-Borne Encephalitis: The Importance of Booster Vaccinations throughout Life [0.03%]
成人及老年人百日咳、白喉、破伤风和蜱传脑炎的疫苗接种：生活中加强剂接种的重要性
Birgit Weinberger
Birgit Weinberger
Immunization strategies for the elderly are frequently perceived as comprising only vaccines against influenza, Streptococcus pneumoniae, and herpes zoster. However, besides these vaccines, which are recommended specifically for the elderly...