The Same Intestinal Inflammatory Disease despite Different Genetic Risk Factors in the East and West? [0.03%]
东西方遗传风险因素不同但炎症性肠病类似？
Rashid N S Lui,Siew C Ng
Rashid N S Lui
Background: Inflammatory bowel disease (IBD) is a chronic inflammatory disease with unknown etiology. It is likely caused by a complex interplay between genetic, immunologic and environmental factors. Although IBD is stil...
The Innate Immune System: A Trigger for Many Chronic Inflammatory Intestinal Diseases [0.03%]
固有免疫系统：多种慢性炎症性肠病的始动因素
Nobuhiko Kamada,Gerhard Rogler
Nobuhiko Kamada
Background: Mononuclear phagocytes, such as monocytes, macrophages, and dendritic cells, are important cellular components of the innate immune system that contribute to the pathogenesis of many intestinal inflammatory di...
Eosinophilic Esophagitis, Eosinophilic Gastroenteritis, and Eosinophilic Colitis: Common Mechanisms and Differences between East and West [0.03%]
嗜酸细胞性食管炎、嗜酸细胞性胃肠炎和嗜酸细胞性结肠炎：相同机制与东西方差异
Shunji Ishihara,Yoshikazu Kinoshita,Alain Schoepfer
Shunji Ishihara
Background: Eosinophilic esophagitis (EoE), eosinophilic gastroenteritis (EGE), and eosinophilic colitis (EoC) have been diagnosed with an increasing frequency over the last decades. All these diseases share pathogenic si...
The Role of T-Cell Subsets in Chronic Inflammation in Celiac Disease and Inflammatory Bowel Disease Patients: More Common Mechanisms or More Differences? [0.03%]
共病乳糜泻和炎症性肠病患者的慢性炎性疾病中T细胞亚群的作用：更多的共同机制还是差异？
Tadakazu Hisamatsu,Ulrike Erben,Anja A Kühl
Tadakazu Hisamatsu
Background: Chronic intestinal inflammation due to noninfectious causes represents a growing health issue all over the world. Celiac disease as well as inflammatory bowel diseases (IBD) like Crohn's disease and ulcerative...
Gerhard Rogler,Toshifumi Hibi
Gerhard Rogler
Intestinal Fibrosis and Liver Fibrosis: Consequences of Chronic Inflammation or Independent Pathophysiology? [0.03%]
肠道纤维化和肝脏纤维化：慢性炎症的后果还是独立的病理生理过程？
Florian Rieder,Dominik Bettenworth,Jin Imai et al.
Florian Rieder et al.
Background: Intestinal fibrosis and liver fibrosis represent a significant burden for our patients and health-care systems. Despite the severe clinical problem and the observation that fibrosis is reversible, no specific ...
Hiroshi Fukui,Reiner Wiest
Hiroshi Fukui
Background: Understanding of the gut-liver axis is important for the up-to-date management of liver cirrhosis, and changes of intestinal functions form the core of this interesting research field. ...
Ulcerative Colitis with and without Primary Sclerosing Cholangitis: Two Different Diseases? [0.03%]
伴有和不伴原发性硬化性胆管炎的溃疡性结肠炎是两种不同的疾病吗？
Atsushi Tanaka,Joachim C Mertens
Atsushi Tanaka
Background: Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease of unknown origin and an important hepatobiliary complication of inflammatory bowel diseases (IBD), especially ulcerative colitis (UC...
Inflammatory Intestinal Diseases: Why Do We Need Another Gastroenterology Journal? [0.03%]
炎症性肠病：为何需要另一本胃肠病学期刊？
Gerhard Rogler,Toshifumi Hibi
Gerhard Rogler
Asians have more perianal Crohn disease and ocular manifestations compared with white Americans [0.03%]
与白人美国人相比，亚洲人的克罗恩病累及 peri-anal部位以及眼部的比例更高
Bharati Kochar,Edward L Barnes,Hans H Herfarth et al.
Bharati Kochar et al.
Background: Inflammatory bowel disease (IBD) is increasing in Asians. We sought tobetter understand differences in IBD between Asians and whites in the United States (U.S.). ...