Multi-Targeting CAR-T Cell Strategies to Overcome Immune Evasion in Lymphoid and Myeloid Malignancies [0.03%]
针对淋巴和骨髓恶性肿瘤免疫逃逸的多靶点CAR-T细胞策略
Jessica Peter,Fabio Toppeta,Alexandre Trubert et al.
Jessica Peter et al.
Background: Chimeric antigen receptor (CAR)-T cell therapy has become a groundbreaking treatment for hematological malignancies, particularly lymphomas and multiple myeloma, with high remission rates in refractory and rel...
Highlights of Translational and Molecular Research Presented at the European Society for Medical Oncology Annual Meeting 2024 [0.03%]
欧洲医学肿瘤学会2024年会上展示的转化和分子研究亮点
Carolin Krekeler,Verena Turco,Annabel Helga Sophie Alig et al.
Carolin Krekeler et al.
Artificial Intelligence and Gynecological Oncology: A Comparative Study of ChatGPT-Omni and Gemini-Pro Across Repeated Intervals with Case Scenario and Open-Ended Queries [0.03%]
人工智能与妇科肿瘤学：在重复间隔中使用案例场景和开放性查询对ChatGPT-Omni和Gemini-Pro进行比较研究
Seckin Tuna Kaplan
Seckin Tuna Kaplan
supporting clinical decision-making, diagnosis, and treatment. The study aims to compare the performance of ChatGPT-4o (Omni) and Gemini-pro in answering clinical questions and case scenarios related to gynecological oncology and to assess ...
Effect of Early Tumor Shrinkage and Depth of Response on the Clinical Outcomes of Patients with Unresectable Hepatocellular Carcinoma Treated with Transcatheter Arterial Chemoembolization and Lenvatinib Plus PD-1 Inhibitors [0.03%]
早期肿瘤缩小和深度缓解对不可切除的肝细胞癌患者经动脉化疗栓塞联合仑伐替尼加PD-1抑制剂治疗临床结局的影响
Xiaobing Zhang,Zhemin Shen,Shuping Qu et al.
Xiaobing Zhang et al.
Introduction: Systematic therapies, including tyrosine kinase inhibitors (TKIs) and immune checkpoint inhibitors (ICIs), have now been approved as the mainstay treatment for patients with unresectable hepatocellular carci...
Modifications to prostate cancer diagnosis following COVID-19 and following models [0.03%]
COVID-19及模型对前列腺癌诊断的改变
Miroslav Stojadinovic,Milorad Stojadinovic,Slobodan Jankovic
Miroslav Stojadinovic
Introduction: The COVID-19 pandemic has impacted the treatment of prostate cancer (PCa). The study examines any predictions that could point to future models. ...
Improving Accuracy and Source Transparency in Responses to Soft Tissue Sarcoma Queries using GPT-4o Enhanced with German Evidence-Based Guidelines [0.03%]
利用增强德国循证指南的GPT-4o提高对软组织肉瘤查询响应的准确性和来源透明度
Cheng-Peng Li,Wei-Wei Jia,Yuan Chu et al.
Cheng-Peng Li et al.
Introduction: This study aimed to evaluate the effectiveness of GPT-4o, with and without Retrieval-Augmented Generation (RAG), in responding to soft tissue sarcoma (STS)-related queries. ...
Liquid Biopsy in early breast cancer Will minimal residual disease monitoring be part of routine surveillance? [0.03%]
液体活检在早期乳腺癌中的应用 仍将最小残留病检测作为常规监测的一部分吗？
Kerstin Pfister,Henning Schäffler,Sophia Huesmann et al.
Kerstin Pfister et al.
Background: Current breast cancer (BC) surveillance is limited to the detection of local, locoregional or contralateral recurrence. This is based on two outdated studies from the 1990s and ignores current evidence on liqu...
Impact of epidural anesthesia on the outcome of elderly patients with endometrial cancer - results of a propensity score matched analysis [0.03%]
硬膜外麻醉对老年子宫癌患者预后的影响——倾向评分匹配分析的结果
Valerie Catherine Linz,Marco Johannes Battista,Regina Hummel et al.
Valerie Catherine Linz et al.
Introduction: Epidural anesthesia is a standard procedure to mitigate pain during surgery for endometrial cancer (EC). Little data exist about the influence of epidural anesthesia on the oncological outcome in elderly pat...
Tumor Infiltrating Lymphocytes, CAR-, and T Cell Receptor- Modified T Cells in Solid Cancer Oncology [0.03%]
肿瘤浸润淋巴细胞、CAR-T和TCR-T细胞在实体瘤中的应用
Hakim Echchannaoui,Kevin Jan Legscha,Matthias Theobald
Hakim Echchannaoui
Background: Adoptive cellular therapy (ACT) is a promising treatment approach aiming at enhancing T cell antitumor immune response. ACT includes tumor-infiltrating lymphocytes (TILs), chimeric antigen receptor (CAR) and T...
Molecular tissue profiling in a clinically selected pancreatic cancer cohort [0.03%]
临床选择的胰腺癌队列的分子组织学谱分析
Stefanie Hegenberg,Tobias Germing,Elena Schlageter et al.
Stefanie Hegenberg et al.
Introduction: Pancreatic ductal adenocarcinoma (PDAC) is a challenging malignancy and precision oncology treatment options may improve patient outcomes. Next-generation sequencing (NGS) is an established tool that enables...