Aurora Kinases in Ocular Malignancies: Functional Significance and Potential Implications [0.03%]
虹膜激酶在眼部恶性肿瘤中的功能意义及潜在影响
Saswati S Lenka,Naheed Arfin Borah,Soumya Sucharita et al.
Saswati S Lenka et al.
Background: Ocular malignancies are rare compared to tumors affecting other organs. The treatment options for these cancers remain limited, mostly restricted to nonspecific chemotherapeutic drugs, radiation therapy, and s...
Ultrasound Biomicroscopy in the Diagnosis and Management of Iris and Ciliary Body Tumors: A Comprehensive Review [0.03%]
超声生物显微镜在诊断和治疗虹膜和睫状体肿瘤中的应用:全面回顾
Dibya Prabha,Arun D Singh,Vishal Raval
Dibya Prabha
Background: Although uncommon, tumors of the iris and ciliary body present significant diagnostic challenges because of their variable appearance and overlap between benign and malignant features and the difficulty of dir...
Retinocytoma: Clinical and Genetic Characteristics in 16 Pediatric and Adult Cases [0.03%]
视网膜细胞瘤的临床和遗传特征:16例儿童及成人患者的分析
Chloé Widehen,Nathalie Cassoux,Denis Malaise et al.
Chloé Widehen et al.
Introduction: Retinocytomas are rare benign intraocular tumors that may mimic spontaneously regressed retinoblastoma (Rb). Materials and methods: ...
Seth T Kazmer,Rachel Frauches,Carlo Galang et al.
Seth T Kazmer et al.
Introduction: Uveal melanocytomas are benign melanocytic proliferations characterized histologically by large polyhedral cells, abundant intracytoplasmic melanin, small centrally located nuclei, and low nuclear-to-cytopla...
Dramatic Inflammatory Regression of Choroidal Metastases from Renal Cell Carcinoma following Ipilimumab and Nivolumab Immunotherapy: A Case Series [0.03%]
伊匹单抗和纳武单抗免疫治疗后肾细胞癌脉络膜转移的炎症消退:一系列病例
Carter W Lim,Kirk A J Stephenson,Katherine E Paton
Carter W Lim
Introduction: Renal cell carcinoma (RCC) is a rare cause of ophthalmic metastasis. Immune checkpoint blockers (ICBs) such as ipilimumab and nivolumab (ipi/nivo) are first-line therapies for advanced RCC. There are limited...
Belzutifan for Ocular Tumors in Patients with von Hippel-Lindau Disease [0.03%]
用于von Hippel-Lindau病患者的视网膜血管瘤病治疗药物Belzutifan治疗眼部肿瘤
Farzad Jamshidi,Samuel Tadros,Lola Lozano et al.
Farzad Jamshidi et al.
Background: Belzutifan is an orally administered small molecule inhibitor of HIF-2-alpha that has been approved for use in von Hippel-Lindau (VHL)-associated renal cell carcinoma, central nervous system (CNS) hemangioblas...
Malcolm Wiseman Jr,Timothy Fuller,R Nick Hogan et al.
Malcolm Wiseman Jr et al.
Introduction: Most uveal melanomas (UMs) are readily diagnosed based on their characteristic features, but they can occasionally pose a diagnostic challenge, such as when they present as an inflammatory mass. We present 2...
Retinal Capillary Haemangioblastoma: Clinical Spectrum, Imaging Insights, and Treatment Strategies [0.03%]
视网膜毛细血管横纹肌瘤:临床谱系、影像学见解和治疗策略
Ramesh Venkatesh,Chaitra Jayadev,Vishma Prabhu et al.
Ramesh Venkatesh et al.
Background: Retinal capillary haemangioblastoma (RCH) is a benign but potentially vision-threatening vascular tumour of the retina. It may occur sporadically or as multifocal, bilateral lesions in association with von Hip...
In Need of Structured Recovery, Ocular Oncology Needs Enhanced Recovery after Surgery [0.03%]
亟需系统性恢复,眼癌手术后康复需求增强
Paige Campbell,Ezekiel Weis,Adam Michael Wandzura et al.
Paige Campbell et al.
The Potential Role of Hyperspectral Retinal Imaging of Choroidal Tumors [0.03%]
超光谱视网膜成像在脉络膜肿瘤中的潜在作用
Darvy Dang,Xavier Hadoux,Rod ODay
Darvy Dang
Background: Early and accurate diagnosis of choroidal tumors including benign nevi, melanomas, and vascular lesions is essential for effective clinical management. Conventional imaging techniques such as fundus photograph...