Julia E Blower,Jayanta K Bordoloi,Alex Rigby et al.
Julia E Blower et al.
Background: Multi-tracer PET/SPECT imaging enables different modality tracers to be present simultaneously, allowing multiple physiological processes to be imaged in the same subject, within a short time-frame. Fluorine-1...
A Review of New High-Throughput Methods Designed for Fluorescence Lifetime Sensing From Cells and Tissues [0.03%]
用于细胞和组织荧光寿命检测的新高通量方法综述
Aric Bitton,Jesus Sambrano,Samantha Valentino et al.
Aric Bitton et al.
Though much of the interest in fluorescence in the past has been on measuring spectral qualities such as wavelength and intensity, there are two other highly useful intrinsic properties of fluorescence: lifetime (or decay) and anisotropy (o...
Optimizing Diffusion Imaging Protocols for Structural Connectomics in Mouse Models of Neurological Conditions [0.03%]
优化小鼠神经疾病模型结构连接组学弥散成像协议
Robert J Anderson,Christopher M Long,Evan D Calabrese et al.
Robert J Anderson et al.
Network approaches provide sensitive biomarkers for neurological conditions, such as Alzheimer's disease (AD). Mouse models can help advance our understanding of underlying pathologies, by dissecting vulnerable circuits. While the mouse bra...
A Highly Sensitive Time-Gated Fluorescence Immunoassay Platform Using Mn-Doped AgZnInS/ZnS Nanocrystals as Signal Transducers [0.03%]
一种高灵敏的时间门控荧光免疫分析平台使用Mn掺杂的AgZnInS/ZnS纳米晶体作为信号转换器
Brandon Gallian,Masoumeh Saber Zaeimian,Derrick Hau et al.
Brandon Gallian et al.
In this work, a time-gated immunoassay platform using low-energy excitable and fluorescence long-lived Mn:AgZnInS/ZnS nanocrystals as signal transducers was developed and applied to the detection of the capsular polysaccharide (CPS) of Burk...
Ricardo Ramirez,Yu-Chiao Chiu,Allen Hererra et al.
Ricardo Ramirez et al.
Background: Cancer has been a leading cause of death in the United States with significant health care costs. Accurate prediction of cancers at an early stage and understanding the genomic mechanisms that drive cancer dev...
Predicting sites of epitranscriptome modifications using unsupervised representation learning based on generative adversarial networks [0.03%]
基于生成对抗网络的无监督表示学习预测表转录组修饰位点
Sirajul Salekin,Milad Mostavi,Yu-Chiao Chiu et al.
Sirajul Salekin et al.
Epitranscriptome is an exciting area that studies different types of modifications in transcripts and the prediction of such modification sites from the transcript sequence is of significant interest. However, the scarcity of positive sites...
Biomedical Research Programs at Present and Future High-Energy Particle Accelerators [0.03%]
当前和未来的高能粒子加速器上的生物医学研究项目
Vincenzo Patera,Yolanda Prezado,Faical Azaiez et al.
Vincenzo Patera et al.
Biomedical applications at high-energy particle accelerators have always been an important section of the applied nuclear physics research. Several new facilities are now under constructions or undergoing major upgrades. While the main goal...
Marco Durante,Katia Parodi
Marco Durante
Heavy ion therapy can deliver high doses with high precision. However, image guidance is needed to reduce range uncertainty. Radioactive ions are potentially ideal projectiles for radiotherapy because their decay can be used to visualize th...
Fluocell for Ratiometric and High-Throughput Live-Cell Image Visualization and Quantitation [0.03%]
用于比值型和高通量活细胞图像可视化与定量的荧光功能化细胞传感器技术（FluoCell）
Qin Qin,Shannon Laub,Yiwen Shi et al.
Qin Qin et al.
Spatiotemporal regulation of molecular activities dictates cellular function and fate. Investigation of dynamic molecular activities in live cells often requires the visualization and quantitation of fluorescent ratio image sequences with s...
Devin L Harrison,Yun Fang,Jun Huang
Devin L Harrison
A T cell is a sensitive self-referential mechanical sensor. Mechanical forces influence the recognition, activation, differentiation, and function throughout the lifetime of a T cell. T cells constantly perceive and respond to physical stim...