Improved longevity and in vivo performance of neurotransmitter detection using 30 µm cone-shaped carbon fiber microelectrode [0.03%]
一种改进的神经递质检测方法及其在体表现性能良好且直径为30µm的锥形碳纤维微电极
Haeun Kwon,Hyun-U Cho,Jeongeun Sim et al.
Haeun Kwon et al.
Fast Scan Cyclic Voltammetry (FSCV) is a widely used electrochemical technique to detect rapid extracellular dopamine transients in vivo. It employs carbon fiber microelectrodes (CFMEs), but conventional 7 µm diameter CFMEs often suffer fr...
Identification of critical process parameters and quality attributes for bioreactor-based expansion of human MSCs [0.03%]
基于生物反应器的人类MSCs扩增关键工艺参数及质量属性的鉴定
Laura Herbst,Bastian Nießing,Robert H Schmitt
Laura Herbst
Mesenchymal stem/stromal cells (MSCs) have been identified as a promising therapeutic option for osteoarthritis, graft vs. host disease and cardiovascular diseases, among others. For widespread application of these therapies, robust and sca...
Finite element and preclinical analysis of tissue response to negative pressure wound therapy with a felted foam containing 10 mm through holes [0.03%]
含10毫米贯穿孔的成型泡沫负压伤口治疗的有限元和临床前分析
Amy K McNulty,Robert P Wilkes,Brenda Marchand et al.
Amy K McNulty et al.
Introduction: Not all wound patients are candidates for surgical debridement. A felted, reticulated open cell foam with an array of 10 mm holes (VFCC) for use with instillation therapy has been used to eliminate non-viabl...
Personalized porous tantalum implants crafted via 3D printing: new horizons in complex cervical-thoracic spinal fusion [0.03%]
个性化多孔钽假体植入物的３Ｄ打印制备及其在颈胸椎复杂脊柱融合中的应用展望
Chang Chen,Huaquan Fan,Ge Chen et al.
Chang Chen et al.
Background: Complex interbody fusion remains challenging, while traditional surgical instruments are not suitable for complex spinal deformities. Porous tantalum (Ta) has excellent osteogenic properties, but there is curr...
Engineering a 3D wounded skin equivalent to study early inflammatory and regenerative responses in vitro [0.03%]
工程化3D损伤皮肤模型以体外研究早期炎症和再生反应
Rima Nuwayhid,Nguyen Ngoc-Huyen,Dmitry Notov et al.
Rima Nuwayhid et al.
Introduction: Traditional models for studying wound healing, including 2D cell cultures and animal models, present substantial limitations in mimicking human skin physiology. In this study, we present a three-dimensional ...
Dynamic male mouse gut microbiota signature linked to improved wound healing of a novel salecan hydrogel dressing [0.03%]
动态的雄性小鼠肠道微生物群标志物与新型褐藻胶伤口敷料促进伤口愈合相关
Guangping Luo,Tongtong Zhang,Yanan Jiang et al.
Guangping Luo et al.
Salecan-based hydrogel (thereafter called Sal-hydrogel) dressings and gut microbiota have been associated with enhanced wound healing. However, the relationship between these two factors remains unclear. This study investigated the dynamic ...
Effective detection of staphylococcal infections in human bone tissue using combined raman microscopy and micro-computed tomography [0.03%]
结合拉曼显微镜和微型计算机断层扫描有效检测人类骨组织中的葡萄球菌感染
Richard Andreas Lindtner,Lukas Kampik,Larissa Noack et al.
Richard Andreas Lindtner et al.
Bone infections caused by Staphylococcus aureus and Staphylococcus epidermidis are serious complications in orthopedic surgery. These infections commonly occur in joint replacements, fracture management, and bone grafting procedures. Rapid ...
3D bioprinting patient-specific grafts for tendon/ligament repair in motion: emerging trends and challenges [0.03%]
用于运动中肌腱/韧带修复的个性化移植物的3D生物打印：新兴趋势与挑战
Xuejian Bai,Yihan Yang,Jinwei Chu et al.
Xuejian Bai et al.
Tendon/ligament (T/L) injuries sustained during motion are highly prevalent and severely impact athletes' careers and quality of life. Current treatments, including autografts, allografts, and synthetic ligaments, have limitations such as d...
3D-printed copper-containing tailored titanium alloys with corrosion resistance, biocompatibility, and anti-inflammatory properties for enhanced guided bone regeneration [0.03%]
一种用于引导骨再生的增强型抗腐蚀、生物相容性和抗炎含铜钛合金的3D打印技术
Lan Luo,Quan Zhong,Zi-Qin Chen et al.
Lan Luo et al.
Introduction: Guided bone regeneration (GBR) serves as a critical technique in dental implantology, relying heavily on barrier membranes for successful alveolar bone augmentation. Titanium mesh, widely utilized in GBR pro...
Alternating 2D and 3D culture reduces cell size and extends the lifespan of placenta-derived mesenchymal stem cells [0.03%]
间叶干细胞交替二维和三维培养减少细胞大小并延长胎盘来源的间充质干细胞寿命
Ying Pan,Li Han,Yakun Yang et al.
Ying Pan et al.
Background: Mesenchymal stem cells (MSCs) hold great promise for treating a variety of human diseases; however, their clinical translation is hindered by challenges in large-scale expansion while preserving therapeutic po...