Innovative advances in microalgal high-value products: unlocking potential from bioprocessing to bioindustrial applications [0.03%]
微藻高价值产品的创新进展：从生物加工到生物工业应用的潜力挖掘
Abdulrahman Alqahtani,Bayan Altoaimi
Abdulrahman Alqahtani
Microalgae are increasingly recognized as industrial biotechnology platforms for the sustainable production of high-value products (HVPs), including carotenoids, polyunsaturated fatty acids (PUFAs), polysaccharides, and phycobiliproteins. T...
Xiong Shen,Hanlin Li,Tingting Liu et al.
Xiong Shen et al.
Purpose: To achieve ultrasound molecular imaging (UMI) of various tumor types, this study developed a novel integrin-targeted probe, RGD-hGVs, based on gas vesicles (GVs) derived from Halobacterium salinarum NRC-1 (Halo) ...
Glucose concentration modulates bovine intervertebral disc response under physiological loading [0.03%]
葡萄糖浓度调节牛椎间盘生理负载下的响应
D Zuncheddu,M Muerner,K Klavins et al.
D Zuncheddu et al.
Introduction: Ex vivo organ culture is a widely accepted model in intervertebral disc (IVD) research, providing valuable insights into pathology and potential new treatments. Many ex vivo culture protocols utilize high co...
Cancer metastasis in vitro models - can 3D biofabrication and microfluidics sow the seeds in the right soil [0.03%]
基于3D生物制造和微流控的体外癌症转移模型-能否在合适的土壤中播种？
Yordan Sbirkov,Ilian Koev,Azad Ozanian et al.
Yordan Sbirkov et al.
More than 140 years after the first observations that cancer cells spread to secondary sites nonrandomly, the lack of representative pre-clinical models of metastasis precludes our understanding of the processes of metastasis. The developme...
Peripheral blood-derived mesenchymal stem cells in osteochondral repair: a perspective on emerging insights and future directions [0.03%]
基于外周血来源的间充质干细胞在骨软骨修复中的作用：新兴研究洞察与未来方向的观点综述
Senthilkumar Rajendran,Pier Paolo Parnigotto,Antara Banerjee et al.
Senthilkumar Rajendran et al.
Mesenchymal stem cells (MSCs) isolated from peripheral blood (PB) are gaining increasing attention among both researchers and clinicians, representing a promising alternative to traditional stem cell sources such as bone marrow and adipose ...
Inhibiting Nampt signaling promotes M2 macrophage polarization to enhance bone regeneration in periodontitis [0.03%]
抑制Nampt信号促进M2型巨噬细胞极化以增强牙周炎骨再生
Yixin Xia,Kexin Xie,Chunhui Liao et al.
Yixin Xia et al.
Background: Dysregulated macrophage polarization is a fundamental cause of bone loss in periodontitis. However, the role of nicotinamide phosphoribosyltransferase (NAMPT) in macrophage regulation within periodontitis rema...
A multifunctional conductive physiomimetic scaffold: synergy of rGO coating and cannabis-derived nanotopography for infection-resistant bone repair [0.03%]
一种多功能导电生理仿生支架：rGO涂层与大麻素纳米拓扑结构协同作用的抗感染骨修复材料
Fateme Hojaty Saeedi,Hosein Shahsavarani,Saadi Hosseini et al.
Fateme Hojaty Saeedi et al.
Conventional bone grafts cannot reliably fulfill the dual requirements of rapid osseoinduction and intrinsic infection-resistance to meet clinical needs. We therefore aimed to overcome this dual challenge by fabricating a novel physiomimeti...
Multiple plant growth-promoting bacteria enhance rice growth in non-grain-converted lands [0.03%]
多种植物促生细菌可促进非耕地上水稻生长
Xuqing Li,Wu Ying,Munazza Ijaz et al.
Xuqing Li et al.
China faces a continuously growing food demand, while a large proportion of its cultivated land is increasingly being shifted to non-grain plantation, leading to widespread soil fertility degradation and microbial community imbalance in lan...
Integrating diagnosis and therapy in hepatocellular carcinoma: advances in nanotheranostics [0.03%]
肝细胞癌的诊疗整合：纳米治疗诊断学的新进展
Jiansong Shen,Yanyan Wen,Sixue Wu et al.
Jiansong Shen et al.
Hepatocellular carcinoma (HCC) poses significant challenges in early diagnosis and effective treatment, leading to a poor prognosis. The emerging strategy of "theranostics," which integrates diagnostic and therapeutic functions into a singl...
Joshua François,Alina Simerzin,Ashwini Jambhekar et al.
Joshua François et al.
Introduction: Understanding how cells respond to internal and external inputs requires investigating cells within three-dimensional (3D) environments, which better mimic physiological conditions. Compared to two-dimension...