High-throughput optimization of antibody production in CHO cells by tuning heavy- and light-chain promoter strength [0.03%]
通过调节抗体的重链和轻链启动子强度在CHO细胞中实现高通量抗体产量优化
Marzia Rahimi,Anna Christina Adams,Lise M Grav et al.
Marzia Rahimi et al.
Monoclonal antibody (mAb) production in CHO cells depends, among other factors, on balanced co-expression of the heavy (HC) and light (LC) chains. Imbalances between HC and LC can reduce titer, compromise product quality, and negatively aff...
A wearable functional electrical stimulation device with a movable electrode for motor point tracking [0.03%]
一种带有可移动电极的用于监测电机点的外骨骼功能电刺激设备
Yue Liu,Shin Ebihara,Masao Sugi et al.
Yue Liu et al.
Functional electrical stimulation is widely applied in the rehabilitation of individuals with cerebrovascular disease or spinal cord injury but is limited by rapid muscle fatigue. We present a novel stimulation strategy based on real-time m...
Assisting hand gesture classification and rehabilitation assessment via sEMG and finger motion data [0.03%]
基于表面肌电和手指运动数据的手势分类及康复评估辅助技术研究
Xiuxiu Yang,Lingfeng Zhang,Fukui Wu et al.
Xiuxiu Yang et al.
Introduction: To address the lack of integrated and clinically applicable motion capture systems for hand function assessment, we developed a wearable device capable of simultaneously recording finger curvature and surfac...
Elastic, load-bearing and autoclavable protein-based graft for coronary revascularization [0.03%]
一种用于冠状动脉再血管化的弹性、承压和可高压灭菌的基于蛋白质的移植物
Federica Sallustio,Ikram El Maachi,Dominic Pascal Andre et al.
Federica Sallustio et al.
Autologous grafts, such as the internal mammary artery and saphenous vein, are considered the gold standard for coronary artery bypass. However, there is a critical need for small diameter vascular grafts to meet the demands of coronary art...
Biomechanics of medial meniscus tears in the context of pain: a finite element analysis [0.03%]
膝关节内侧半月板撕裂的生物力学与疼痛关系：有限元分析
Karol Daszkiewicz,Piotr Łuczkiewicz
Karol Daszkiewicz
Introduction: Meniscal tears represent the most common knee pathology and may be associated with pain. Meniscal pain is caused by direct mechanical stimulation of nociceptors located in the outer, vascular part of the men...
GelMA-GelDopa-Sr double-network hydrogel promotes skin regeneration by enhancing angiogenesis and macrophage polarization [0.03%]
明胶甲基丙烯酸酯-多巴-硫酸钙双网络水凝胶通过促进血管生成和巨噬细胞极化来促进皮肤再生
Yuxuan Su,Fang Zhao,Shuang Liu et al.
Yuxuan Su et al.
Introduction: Chronic skin defects typically exhibit persistent inflammation, damaged cell regeneration, and insufficient vascularization, all of which severely impede the healing process. Traditional skin dressings merel...
Effect of rear impact on the instrumented cervical spine: a finite element study [0.03%]
后撞对仪器测量颈椎的影响：有限元研究
Balaji Harinathan,Davidson Jebaseelan,Narayan Yoganandan
Balaji Harinathan
Introduction: Degenerative cervical myelopathy (DCM) is a leading cause of spinal cord dysfunction and often requires surgical decompression and instrumentation. Anterior cervical discectomy and fusion (ACDF) is the most ...
Microfluidic preparation of size- and lamellarity-controlled liposomes using a static mixer and the advantage of a multilamellar structure in biosensing applications [0.03%]
基于静态混合器的微流控法控制制备尺寸和层状结构的脂质体及多层状结构在生物传感中的优势研究
Makoto Kiuchi,Shinji Takeoka,Keitaro Sou
Makoto Kiuchi
Background: Liposomes are useful tools for amplifying signals in biosensing techniques, which are used to detect and analyze biological molecules. The goal of this study is to improve the sensitivity of immunosorbent assa...
Aligned piezoelectric fibrous scaffolds for prevention of traumatic neuroma formation [0.03%]
用于预防创伤性神经瘤形成的压电纤维支架
Yujie Chen,Xinyi Gu,Huiran Zang et al.
Yujie Chen et al.
Purpose: Traumatic neuroma, a painful complication of peripheral nerve injury, arises from disorganized axonal regeneration and chronic inflammation. Existing treatments provide limited relief. This study aimed to evaluat...
Unlocking circular bioeconomy potential of termite-gut yeasts: dual bioremediation and biodiesel production [0.03%]
肠道酵母的圆形生物经济潜力：双重生物修复和生物柴油生产
Sameh S Ali,Min Xiong,Rania Al-Tohamy et al.
Sameh S Ali et al.
Lignin-derived aromatics and synthetic azo dyes are among the most persistent and toxic pollutants released by textile processing, petrochemical industries, pulp-and-paper manufacturing, and agricultural waste streams. Their structural comp...