Tissue-engineered dermal substitutes constructed by human embryonic stem cell-derived fibroblasts facilitate the repair of skin wounds [0.03%]
由人胚胎干细胞来源的成纤维细胞构建的组织工程皮肤替代物可促进皮肤伤口修复
Cui Ge,Lu Yin,Liyuan Jia et al.
Cui Ge et al.
Background: Tissue engineering is an efficient method for constructing functional skin equivalents to treat large-area skin wounds. However, the source of seed cells is limited. ...
Anti-fibrotic effect of Spirulina maxima-derived extracellular vesicles: possible role of PARK7 and HSP70 chaperones [0.03%]
螺旋藻衍生的细胞外囊泡抗纤维化作用：PARK7和HSP70分子伴侣的作用机制探究
Beáta Szebeni,Mária Bernáth,Péter Bokrossy et al.
Beáta Szebeni et al.
Introduction: Spirulina maxima (Sm), a blue-green microalgae, is well known for its rich nutritional composition, antioxidant, and anti-inflammatory properties. In this study, we found that small extracellular vesicles (s...
Intra-articular delivery of Si-Vangl2 limits cartilage degeneration in an osteoarthritis rat model [0.03%]
关节内递送Si-Vangl2蛋白限制骨关节炎模型中的软骨退变
Peiru Li,Ke Zhang,Zhuoying Li et al.
Peiru Li et al.
Osteoarthritis (OA) is driven by progressive cartilage degeneration associated with dysregulated chondrocyte metabolism and inflammatory signaling, for which effective disease-modifying treatments remain limited. In this study, we observed ...
Modeling the effects of routine screening for accidental lab-acquired infections on the risk of potential pandemic pathogen escape from high-biosafety research facilities [0.03%]
建模评估常规筛查意外实验室获得性感染对高生物安全研究设施中潜在大流行病原菌泄漏风险的影响
Byron Cohen,Boyu Ren,William Hanage et al.
Byron Cohen et al.
Introduction: Accidental lab-acquired infections (LAIs) risk releasing potential pandemic pathogens from high-biosafety (BSL-3 or BSL-4) research facilities. We constructed a stochastic network infectious disease model to...
Integrating 3D bioprinting and neural stem cell therapy for central nervous system repair: implications for regenerative neurosurgery [0.03%]
结合3D生物打印和神经干细胞疗法进行中枢神经系统修复的再生神经外科意义
Yupeng Guo,Xuanwei Dong,Min Liu et al.
Yupeng Guo et al.
The limited regenerative capacity of the central nervous system (CNS)poses a major challenge in neurosurgical interventions for spinal cord injuries, neurodegenerative diseases,and traumatic brain injuries. Traditional approaches offer stru...
Engaging U.S. experts in environmental oversight of GE crops as it relates to novel biotechnologies [0.03%]
美国专家参与环境监管转基因作物及其新型生物技术的影响
Nick Loschin,Catherine E Sanders,Khara Grieger
Nick Loschin
Advances in agricultural biotechnologies, including gene editing and other new genomic techniques, are expanding the range of organisms, traits, and applications being released into the environment. Questions have been raised about the adeq...
Finite element analysis-based optimization of longitudinal bending stiffness and rearfoot stability in carbon-plated running shoes [0.03%]
基于有限元分析的碳板跑鞋纵向弯折刚度和后跟稳定性的优化
Sewon Kim,Youngbin Lim,Siwoo Jung et al.
Sewon Kim et al.
Introduction: The carbon-plated midsole in running shoes plays a pivotal role in enhancing the runner's performance by storing and releasing energy. A key factor in running shoes is the Longitudinal Bending Stiffness (LBS...
Proteomic evaluation and comparison of native and decellularized human saphenous vein extracellular matrices [0.03%]
人隐静脉原生和脱细胞血管外基质的蛋白质组评价及比较研究
Essi M Niemi,Tuula A Nyman,Håvard Attramadal et al.
Essi M Niemi et al.
Background: The growing prevalence of cardiovascular diseases (CVDs) has created an increasing demand for alternative biologically functional vascular grafts. Among the explored tissue engineering strategies, decellulariz...
Autofluorescence lifetime of gelatin-methacrylate hydrogels is sensitive to changes in crosslinking and post-gelation pH [0.03%]
明胶-甲基丙烯酸盐水凝胶的自体荧光寿命可反映交联和凝胶后pH变化情况
Marcos R Rodriguez,Kyle P Quinn
Marcos R Rodriguez
Introduction: There are limited tools to non-destructively evaluate the physicochemical properties of biomaterials in in vivo and in vitro settings. Here, we evaluate the autofluorescence of gelatin-methacrylate (GelMA) h...
Harnessing biogenic nanoparticles for combating antibiotic resistance: green synthesis, mechanistic insights, and biotechnological applications [0.03%]
利用生物基因纳米颗粒对抗抗生素耐药性：绿色合成、机制洞察和生物技术应用
Emad M Abdallah,Abdulrahman Mohammed Alhudhaibi,Ibrahim Mohammed Hussaini et al.
Emad M Abdallah et al.
Antimicrobial resistance (AMR) continues to escalate worldwide, reducing the effectiveness of existing antibiotics and leading to an urgent need for alternative antimicrobial strategies. Biogenic nanoparticles (BNPs) are nanomaterials synth...