Histological and biological evaluation of wheat straw-derived nanocellulose in a rat model of cutaneous wound healing [0.03%]
基于小麦秸秆的纳米纤维素在大鼠皮肤伤口愈合模型中的组织病理学和生物学评价
Nahidah Ibrahim Hammadi,Ahmed J Alfahdawi,Athraa Basheer Radhi et al.
Nahidah Ibrahim Hammadi et al.
Background: Healing of cutaneous wound is a complex biological process that requires the migration of fibroblasts, production of extracellular matrix (ECM) component, angiogenesis and a highly regulated expression pattern...
Design considerations for miniaturized biosensor-enabled systems for older adults: insights from participatory design [0.03%]
参与式设计在老年人适用的微型生物传感器系统中的设计考虑因素：见解
Mia Quidato,Merlin Teodosia Suarez,Ryan Ebardo
Mia Quidato
Miniaturized technologies, including small, portable, or wearable devices such as biosensors, smartwatches, and implantable devices, are transforming health and wellness by enabling real-time, personalized monitoring and interventions, offe...
Genetically reprogrammed BMSCs with Lamin B1 depletion enhance bone regeneration for osteoporosis therapy [0.03%]
基因重编的Lamin B1低表达骨髓间充质干细胞促进骨缺损修复及防治osteoporosis
Xuekun Fu,Shaochuan Huo,Chunhao Cao et al.
Xuekun Fu et al.
Background: Mesenchymal stem cell (MSC) dysfunction contributes to impaired bone regeneration in osteoporosis. Lamin B1, a nuclear lamina protein implicated in stem cell aging, has an unclear role in osteogenesis. ...
A novel chitosan-collagen bilayer scaffold prevents contraction and accelerates cutaneous repair in a rat splint-skin model [0.03%]
新型壳聚糖-胶原蛋白双层支架可防止收缩并加速大鼠外固定皮肤模型的皮肤修复
Priya Das,Matthew McGrath,Noof Sulaiman et al.
Priya Das et al.
Introduction: The treatment of chronic wound is extremely challenging and is often exacerbated by inflammation, poor angiogenesis and recurrent bacterial infections. To address this, we have developed a novel biomimetic b...
Yi-Chen Chen,Shuo-Wen Hsu,Eisuke Shimokita et al.
Yi-Chen Chen et al.
The systematic culling of male layer chicks raises ethical concerns, leading to bans in Germany and other European countries and spurring the search for reliable in-ovo sexing methods. Most existing strategies rely on integration of exogeno...
Development and pre-clinical evaluation of an isosorbide-based pit and fissure sealant achieving low polymerization shrinkage and high biocompatibility [0.03%]
一种新型糖醇基窝沟封闭剂的研制及前期评价研究
Ming Zhang,Yinan Cui,Su Yang et al.
Ming Zhang et al.
Objectives: Resin-based sealants (RBSs) are widely used to prevent pit and fissure caries in clinical dentistry. However, their high density of C=C double bonds leads to volumetric shrinkage during photo-polymerization, w...
Reactive oxygen species in skin diseases: pathogenic mechanisms and nanomaterial-based therapeutic strategies [0.03%]
皮肤病中的活性氧：致病机制和基于纳米材料的治疗策略
Qi Yan,Yu Zheng,Long Chen et al.
Qi Yan et al.
Reactive oxygen species (ROS) are inevitable by-products of aerobic metabolism and play a dual role in skin physiology and pathology. At physiological levels, ROS act as essential second messengers regulating cellular signaling and maintain...
Neuro-immune-vascular-stem cell crosstalk in bone/cartilage regeneration: mechanisms, technological advances, and clinical perspectives [0.03%]
骨/软骨再生中的神经免疫血管干细胞相互作用：机制、技术进展和临床应用前景
Zhichao Liu,Haiyan Fan,Yun Yang
Zhichao Liu
Functional regeneration of bone and cartilage remains an urgent clinical challenge in orthopedics, as its repair process involves the synergistic participation of multiple systems and cell types. Traditional studies have mostly focused on t...
Tianfei Zheng,Dongfeng Guo,Yaqi Shi et al.
Tianfei Zheng et al.
Microbial communities play pivotal roles in the fermentation of cigar tobacco leaves. Although high-throughput sequencing technology has facilitated the exploration of these communities, a comprehensive understanding of their assembly mecha...
Reactive oxygen species accelerated glycation for oxygen-independent corneal cross-linking [0.03%]
氧依赖性角膜交联的活性氧加速糖基化方法
Jiashuai Fan,Sinisa Vukelic
Jiashuai Fan
Background: The pentose-initiated Maillard reaction may serve as an oxygen-independent, non-enzymatic crosslinking (CxL) mechanism, but its slow kinetics limit clinical applicability. We hypothesize that glycation-mediate...