Growth factor-free chondrogenesis and immunomodulation of Wharton's jelly MSCs on chitosan-hyaluronic acid films [0.03%]
无生长因子诱导的Wharton胶源间充质干细胞软骨分化及免疫调节功能检测及其在壳聚糖-透明质酸膜上的诱导分化的研究
Rasha Basso,Ahed Ghamrawi,Bayan Aasar et al.
Rasha Basso et al.
This study explores a surface modification strategy that mimics the native cellular environment through the layer-by-layer assembly of natural polyelectrolytes. Specifically, we developed a multilayer matrix composed of 10 alternating layer...
Tissue maturation and development of mechanical properties in hyaluronic acid bioink-based cartilaginous constructs [0.03%]
透明质酸生物墨水基软骨构建体的组织成熟及力学性能发展规律研究
Paula Büttner,Jessica Faber,Jörg Teßmar et al.
Paula Büttner et al.
Introduction: Bioprinting has emerged as a promising technology for cartilage tissue engineering. In cartilage, the mechanical properties are closely associated with the extracellular matrix (ECM) and of paramount importa...
Treatment of femoral defects in rats with collagen and elastin polymers combined with hydroxyapatite and bone morphogenetic protein [0.03%]
用胶原和弹性蛋白聚合物联合羟基磷灰石及骨形态发生蛋白治疗大鼠股骨缺损
Eduardo Gomes Machado,Marina Ribeiro Paulini,Gustavo Andrade Fraga et al.
Eduardo Gomes Machado et al.
Biomaterials have emerged as promising therapeutic alternatives in clinical conditions in which bone regenerative capacity is limited, whether due to trauma or pathological bone loss. Among these, collagen-based materials, hydroxyapatite (H...
A bioactive heart-derived ECM hydrogel potentiates Astragaloside IV-mediated microvascular regeneration [0.03%]
一种生物活性心脏衍生的ECM水凝胶能增强 Astragaloside IV 介导的微血管再生作用
Yanxing Lan,Zijun Xu,Yajing Li et al.
Yanxing Lan et al.
Impaired microcirculation and insufficient angiogenesis critically limit functional recovery after myocardial infarction (MI), yet effective strategies for localized and sustained vascular regeneration remain lacking. Here, we develop a hea...
Weida Li,Yi Wang,Yue Cui et al.
Weida Li et al.
Joint injuries represent a significant clinical challenge with limited regenerative options. Three-dimensional (3D) bioprinting has emerged as a transformative technology, enabling the precise fabrication of patient-specific, anatomically m...
Shotgun proteomics for biomarker discovery in microbial pathogens and allergens in food: a review [0.03%]
食物中微生物病原体和过敏原的生物标志物发现的鸟枪法蛋白质组学研究综述
Manuel G Amado,Paula Borrajo,Manuel Pazos et al.
Manuel G Amado et al.
Shotgun proteomics has revolutionized protein research by combining liquid chromatography with tandem mass spectrometry (LC-MS/MS), enabling the identification and quantification of proteins in complex mixtures. This technique has significa...
Evidence-based approaches for Empty Nose Syndrome management: a systematic review highlighting current treatments and future directions [0.03%]
基于证据的空鼻综合征管理方法：系统性回顾当前治疗及未来方向
Giulia Galaverni,Davide Adamo,Anjana Chathanchirappattu Raj et al.
Giulia Galaverni et al.
Background: Empty nose syndrome (ENS) is an iatrogenic condition that develops following turbinate surgery. ENS presents with paradoxical nasal obstruction, sensation of suffocation, nasal dryness, accompanied by a substa...
The antimicrobial peptide EM86 loaded to gamma-irradiated sodium alginate/polyvinyl alcohol electrospun nanofibrous dressing treated multidrug-resistant Pseudomonas aeruginosa wound infections in BALB/c mice [0.03%]
辐照的海藻酸钠/聚乙烯醇载抗菌肽EM86纳米纤维敷料治疗BALB/c小鼠多重耐药铜绿假单胞菌感染伤口的研究
Samar Essam Metwally,Hala Abd Allah Farrag,Hassan Ahmed Abd El-Rehim et al.
Samar Essam Metwally et al.
Background: Treating infected wounds is challenging, and conventional dressings delay healing. Resistance to the last-resort antibiotics is on the rise. Antimicrobial peptides (AMPs) offer advantages over traditional anti...
Characterization of the acetabular labrum articular surface and its translation into biomimetic graft design [0.03%]
髋关节盂唇关节面的特征及其在生物仿生移植物设计中的应用
Matthias X T Santschi,Stephanie Huber,Lukas Bienz et al.
Matthias X T Santschi et al.
Background: The acetabular labrum contributes to hip joint stability and lubrication, yet its articular surface properties remain poorly characterized. Understanding and replicating these surface features is critical for ...
Generative tissue modeling for customized biomechanical analysis: a data-driven synthesis framework of simulation-ready 3D shapes [0.03%]
基于生成组织建模的个性化生物力学分析：一种模拟就绪的三维形状数据驱动综合框架
Junmin Ma,Zhi Wang,Zuxing Wu et al.
Junmin Ma et al.
Introduction: Conventional computational modeling of human body and tissue relies on time-consuming reconstruction from medical images. Instead, generative artificial intelligence synthesizes novel samples with few margin...