Task-specific computational fluid dynamics evaluation of multi-outlet extrusion nozzles for bioprinting [0.03%]
用于生物打印的多出口挤出喷嘴的任务特定计算流体动力学评估
Cesar D Vargas Urdaneta,Michael Taynnan Barros
Cesar D Vargas Urdaneta
Introduction: Extrusion bioprinting is transitioning from proof-of-concept demonstrations toward repeatable, manufacturing-style workflows, yet nozzle design remains a key bottleneck. Within compact, opaque channels, bioi...
Phytosynthesis of Ag@AgCl nanoparticles using two types of bionanotechnological protocols exhibiting unique antimicrobial, antioxidant, and anti-inflammatory properties [0.03%]
利用两种类型的生物纳米技术协议的植物合成具有独特抗菌、抗氧化和抗炎性能的Ag@AgCl纳米粒子
Yoshinee Doongoor,Joyce G Soulange,Marek Kolenčík
Yoshinee Doongoor
Introduction: The synthesis of nanomaterials aims to integrate scientific innovation with a commitment to address the UN's Sustainable Development Goals (SDGs). Our study reports two biotechnological protocols for the syn...
Organoid models: reshaping the paradigm for precision development and evaluation of CAR-T cell therapies [0.03%]
类器官模型：重塑CAR-T细胞治疗的精准开发与评估范式
Haipeng Li,Jiaqi Yan,Yuxi Liu et al.
Haipeng Li et al.
Chimeric antigen receptor T (CAR-T) cell therapy has achieved transformative success in hematological malignancies; however, its translation to solid tumors remains severely limited by tumor heterogeneity, immunosuppressive microenvironment...
Revisiting MSC heterogeneity: significance of the CD73+CD39+CD146+ perivascular subset in bone marrow [0.03%]
骨髓中MSC异质性的再探讨：CD73+CD39+CD146+血管周细胞亚群的意义
Ramya Lakshmi Rajendran,Atharva A Mahajan,Byeong-Cheol Ahn et al.
Ramya Lakshmi Rajendran et al.
Quercetin in skin burn healing: mechanisms, advanced delivery systems, and translational perspectives [0.03%]
檞皮素在烧伤创面修复中的作用机制、先进递送系统及转化应用前景
Shanza Rani,Muhammad Saleem Chang,Shuwei Li
Shanza Rani
Burn injuries remain a significant global health challenge, often leading to prolonged healing, infection, and scarring. Addressing these complications requires innovative therapeutic strategies that can accelerate tissue repair and minimiz...
Serum-free production of anti-huCD20(hγ1)-IL2no-alpha immunocytokine: a promising therapeutic for B-NHL [0.03%]
无血清抗人CD20（hγ1）-IL2免疫细胞因子的产生：治疗B细胞非霍奇金淋巴瘤的潜在药物
Debbie Laura Bergantiños Albernas,Ernesto Azahares Valdivia,Carlos Lázaro Pérez Rosales et al.
Debbie Laura Bergantiños Albernas et al.
Introduction: Mammalian cell cultures are widely used for producing complex biopharmaceuticals that require human-like post-translational modifications, such as antibody-based therapeutics. Traditionally, serum-supplement...
Experimental evaluation of a real-time implementation of compensatory reserve measurement in a human model of hemorrhagic shock [0.03%]
失血性休克人体模型中实时补充储备测量的实验评估
Ryan Ortiz,Jose M Gonzalez,Tina Rodgers et al.
Ryan Ortiz et al.
Introduction: The leading cause of preventable traumatic death is hemorrhage. Early detection of hemorrhagic shock remains a critical challenge. For the early prediction of hemorrhagic shock-related cardiovascular decompe...
Substrate stiffness modulates human gingival fibroblast paracrine signaling to promote osteogenic differentiation of human periodontal ligament cells [0.03%]
基质刚度通过调节人牙龈成纤维细胞旁分泌信号促进人牙周膜细胞成骨分化
Watcharaphol Tiskratok,Masahiro Yamada,Maythwe Kyawsoewin et al.
Watcharaphol Tiskratok et al.
Background: Human gingival fibroblasts (HGFs) are stromal cells that maintain periodontal tissue structure and extracellular matrix (ECM) dynamics. ECM stiffness serves as a physical cue that regulates HGF behavior and se...
Standalone methacrylated extracellular matrix for digital light processing bioprinting: a practical workflow [0.03%]
适用于数字光处理生物打印的独立甲基丙烯酸化细胞外矩阵：一种实用的工作流程
Hod Bruck,Shachar Sofer,Aharon Lion et al.
Hod Bruck et al.
Decellularized extracellular matrix (dECM) materials are widely reported to present tissue-specific biochemical cues that influence cell behavior; here, we use porcine uterine dECM as a representative soft-tissue model to operationalize a p...
Artificial intelligence and robotic technologies redefining precision and personalization in orthopedic surgery: a narrative review [0.03%]
人工智能和机器人技术重新定义骨科手术的精准性和个性化：叙述性回顾
Fawwaz Al-Smadi,Sajeda Al-Smadi,Xudong Xie et al.
Fawwaz Al-Smadi et al.
The integration of artificial intelligence and robotic technologies is transforming orthopedic surgery by enhancing diagnostic accuracy, surgical precision, and personalized rehabilitation. This review summarizes the development of these te...