Post-diuretic spot urine sodium assessment in acute heart failure: a retrospective analysis [0.03%]
急性心力衰竭患者利尿后尿钠排泄水平的评估：回顾性分析
Lotte Colson,Simon Vanhentenrijk,Theodoros Kalpakos et al.
Lotte Colson et al.
Aims: To provide real-world data on post-diuretic spot urine sodium concentration (UNa) assessment in acute heart failure (AHF) and its implications for treatment. ...
Absence of cross-toxicity between MET inhibitors in a non-small-cell lung cancer with a MET exon 14 skipping mutation [0.03%]
在MET外显子14跳跃突变的非小细胞肺癌中不存在MET抑制剂之间的交叉毒性
Ariane Vanderick,Benoît Colinet
Ariane Vanderick
Introduction: Selective tyrosine kinase inhibitors are proven effective in patients with non-small lung cancer (NSCLC) with a MET exon 14 skipping mutation. ...
Factors to take into account when interpreting 25-hydroxy-vitamin D serum levels [0.03%]
解读血清25-羟维生素D水平时应考虑的因素
Joris R Delanghe,Marijn M Speeckaert,Thomas Maenhout
Joris R Delanghe
Background: Assessing vitamin D status, typically evaluated using serum or plasma 25-hydroxy vitamin D [25(OH)D] concentration, is complex because of various influencing factors. ...
J Crombez,R H De Staelen
J Crombez
Background: During the health crisis of the COVID-19 pandemic, the adagium was to 'flatten the curve'. We investigate how well countries succeeded in this aim by constructing an appropriate severity measure. It is able to...
Case report: diagnosis of VEXAS syndrome in a patient with therapy-resistant large vessel vasculitis [0.03%]
病例报告：一名难治性大血管炎患者诊断出VEXAS综合征
M Boret,T Malfait
M Boret
VEXAS (Vacuoles, E1 enzyme, X-linked, Auto-Inflammatory, Somatic) syndrome is a recently identified multisystemic auto-inflammatory condition caused by somatic mutations in the UBA1 gene. This syndrome presents diagnostic challenges due to ...
The potential role of vitamin D binding protein in kidney disease: a comprehensive review [0.03%]
维生素D结合蛋白在肾脏疾病中的潜在作用：全面回顾
Joris R Delanghe,Charlotte Delrue,Reinhart Speeckaert et al.
Joris R Delanghe et al.
Chronic kidney disease (CKD) is a growing health concern with a complex etiological landscape. Among the numerous factors implicated, vitamin D binding protein (VDBP) has emerged as a focal point of scientific studies because of its critica...
Development of quality indicators for antimicrobial stewardship in Belgian hospitals: a RAND - modified Delphi procedure [0.03%]
比利时医院抗菌药物管理的质量指标的发展：RAND修改的德尔菲程序
Sylvie Legros,Anna Vanoverschelde,Jens van Krieken et al.
Sylvie Legros et al.
Introduction: Inappropriate antibiotic use is a major cause of antibiotic resistance. Therefore, optimizing antibiotic usage is essential. In Belgium, optimization of antimicrobials for the fight against multidrug resista...
Flemish network on rare connective tissue diseases (CTD): patient pathways in systemic sclerosis. First steps taken [0.03%]
Flemish网络在罕见结缔组织疾病（CTD）中的系统性硬化病患者的治疗路径：迈出第一步
Y Piette,F Van den Bossche,J Aerts et al.
Y Piette et al.
Despite the low prevalence of each rare disease, the total burden is high. Patients with rare diseases encounter numerous barriers, including delayed diagnosis and limited access to high-quality treatments. In order to tackle these challeng...
E Degraeuwe,L Persijn,L Nuytinck et al.
E Degraeuwe et al.
Paediatric clinical trials are critical to ensure that medications prescribed to children are safe and effective. However, evidence-based dosing and labelling of such medications remain limited, and most clinical trials in paediatrics fail....
Joris Delanghe
Joris Delanghe
A public debate idealing with nitrogen (N) emissions is ongoing. Government reports use models in which the major N producers are agriculture and industry. Flemish NOx emission amounted to 26.4 kt N accompanied by an ammonia emission of 34....