Incretin-Based Therapies: A Promising Approach for Modulating Oxidative Stress and Insulin Resistance in Sarcopenia [0.03%]
基于肠泌素的疗法：在 sarcopenia 中调节氧化应激和胰岛素抵抗的一种有前景的方法
Raniah I Alnaser,Fawaz A Alassaf,Mohammed N Abed
Raniah I Alnaser
Background: Recent studies have linked sarcopenia development to the hallmarks of diabetes, oxidative stress, and insulin resistance. The anti-oxidant and insulin sensitivityenhancing effects of incretin-based therapies m...
Denosumab in Osteoporosis: Predicting Long-Term Efficacy beyond 10 Years [0.03%]
Denosumab治疗骨质疏松症：10年以上的长期疗效预测分析
Jeongmin Lee,Youn-Ju Lee,Jeonghoon Ha
Jeongmin Lee
Abdominal Aorta Calcification Identified on DXA Scans and the Risk of Mortality in Adults [0.03%]
双能X线吸收法检查中腹部主动脉钙化与成人死亡风险的关系
Carlos H Orces
Carlos H Orces
Background: Abdominal aortic calcification (AAC) on lateral lumbar radiographs increases the risk of cardiovascular events and mortality. However, data on the association between AAC detected in dual energy X-ray absorpti...
Hyunseong Kang,Ho-Hyup Kim,Chaemoon Lim
Hyunseong Kang
Background: No gold standard exists for bone mineral density (BMD) measurement of the ankle. This study aimed to determine the correlation between bone density using Hounsfield units (HU) based on computed tomography (CT)...
Open, Active-Controlled Clinical Study to Evaluate the Correlation between Whole Body DEXA and BIA Muscle Measurements [0.03%]
一项开放式活性对照临床研究评估全身DEXA和BIA肌量测量的相关性
Yong-Chan Ha,Shinjune Kim,Jun-Il Yoo
Yong-Chan Ha
Background: Dual energy X-ray absorptiometry (DXA) is the gold standard for diagnosing sarcopenia. However, comparative studies using bioelectrical impedance analysis (BIA) would be required in the Korean population. This...
Thioredoxin Interacting Protein Expressed in Osteoblasts Mediates the Anti-Proliferative Effects of High Glucose and Modulates the Expression of Osteocalcin [0.03%]
成骨细胞中表达的硫氧还蛋白相互作用蛋白介导高糖抗增殖效应并调控骨钙素表达
Sarah McGarry,Karen Kover,Francesco De Luca
Sarah McGarry
Background: Hyperglycemia is associated with impaired bone health in patients with diabetes mellitus. Although a direct detrimental effect of hyperglycemia on the bone has been previously reported, the specific molecular ...
Effects of Psychogenic Stress Frequency during the Growth Stage on Oxidative Stress, Organ and Bone Development [0.03%]
生长阶段心因性压力频率对氧化应激、器官及骨骼发育的影响
Sangun Lee,Maho Tairabune,Yuka Nakamura et al.
Sangun Lee et al.
Background: This study aimed to examine the effects of psychogenic stress (PS) frequency on oxidative stress and organ development during growth and to gain fundamental insights into developmental processes during this pe...
Body Composition, Sarcopenia, and Serum Myokines in Acromegaly: A Narrative Review [0.03%]
肢端肥大症的体质成分、肌少症和血清肌肽：综述性文章
Arthur Costa Inojosa,Ana Vitória Hirt Ribeiro,Thaís Florêncio Araújo et al.
Arthur Costa Inojosa et al.
Patients with active acromegaly have a higher percentage of lean body mass, a lower percentage of fat body mass, and an increase in their extracellular water compartment compared to healthy individuals. However, muscle function appears to b...
Antidiabetic Agents and Bone Quality: A Focus on Glycation End Products and Incretin Pathway Modulations [0.03%]
抗糖尿病药物与骨质量：糖基化终末产物及肠促胰素途径调节的作用机制聚焦
Muthanna K Zaki,Mohammed N Abed,Fawaz A Alassaf
Muthanna K Zaki
Diabetes mellitus is associated with inadequate bone health and quality and heightened susceptibility to fractures, even in patients with normal or elevated bone mineral density. Elevated advanced glycation end-products (AGEs) and a suppres...
Two-Year Outcomes of Daily and Twice-Weekly Teriparatide Treatment in Postmenopausal Women with Severe Osteoporosis: A Randomized Non-Blinded Prospective Study [0.03%]
每日及每周两次特立帕肽治疗绝经后严重骨质疏松患者两年的疗效：一项前瞻性随机试验
Takeshi Mochizuki,Koichiro Yano,Katsunori Ikari et al.
Takeshi Mochizuki et al.
Background: The long-term effects of daily teriparatide (D-TPTD) and twice-weekly TPTD (W-TPTD) injections are compared among postmenopausal women with severe osteoporosis. ...