Completing the pieces of a puzzle: in-depth probing of Toxoplasma gondii rhoptry protein 4 as a promising target for vaccination using an in-silico approach [0.03%]
完成拼图的缺失部分:通过计算机模拟方法深入探究束泡蛋白ROP4作为疫苗靶点的潜力
Masoud Foroutan,Mohammad Mehdi Shadravan
Masoud Foroutan
The present study aimed to evaluate the key characteristics of Toxoplasma gondii rhoptry protein 4 (TgROP4), including physicochemical parameters, structural features, immunogenic epitopes, and virtual immune simulation, using several bioin...
Incidence of narcolepsy symptoms after taking COVID-19 vaccines: a Jordanian cross-sectional study [0.03%]
新冠疫苗接种后嗜睡症症状的发病几率——一项约旦横断面研究
Mohammad Al Katatbeh,Yazan Al-Mashakbeh,Hadeel Freihat et al.
Mohammad Al Katatbeh et al.
Purpose: Sleeping disorders were reported in many patients who took vaccines during previous pandemics. We aim to investigate the relationship between coronavirus disease 2019 (COVID-19) vaccines and the incidence of narc...
Immunogenicity of a novel inactivated canine adenovirus type 2 variant vaccine for dogs [0.03%]
一种新型犬腺病毒2型灭活变异疫苗的免疫原性试验
Dong-Kun Yang,Sangjin Ahn,Hye Jeong Lee et al.
Dong-Kun Yang et al.
Purpose: The immunogenicity of vaccines containing the canine adenovirus (CAdV) type 2 (CAdV-2) variant has not yet been reported. We prepared a novel inactivated CAdV-2 variant vaccine using the CAV2232-41 strain, and ev...
The BCG vaccine, advantages, and disadvantages of introducing new generation vaccines against Mycobacterium tuberculosis [0.03%]
BCG疫苗:新一代结核分枝杆菌疫苗的优劣分析
Marzie Mahdizade Ari,Masoumeh Beig,Mohammad Sholeh et al.
Marzie Mahdizade Ari et al.
Tuberculosis (TB) is consistently ranked among the deadliest diseases worldwide, causing millions of deaths annually. Mycobacterium tuberculosis is the causative agent for this infection. Different antibiotics and vaccines have been discuss...
Insights into structural vaccinology harnessed for universal coronavirus vaccine development [0.03%]
结构疫苗学在通用型冠状病毒疫苗开发中的应用得新见解
Chin Peng Lim,Chiuan Herng Leow,Hui Ting Lim et al.
Chin Peng Lim et al.
Structural vaccinology is pivotal in expediting vaccine design through high-throughput screening of immunogenic antigens. Leveraging the structural and functional characteristics of antigens and immune cell receptors, this approach employs ...
SARS-CoV-2 parental vaccination and risk of multisystem inflammatory syndrome in children: a single-center retrospective study [0.03%]
新冠病毒亲代接种与儿童多系统炎症综合征风险的关系:单中心回顾性研究
Raffaele Falsaperla,Vincenzo Sortino,Ausilia Desiree Collotta et al.
Raffaele Falsaperla et al.
Purpose: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) usually causes a mild disease in children and the most serious consequence is multisystem inflammatory syndrome in children (MIS-C). Currently, there a...
The influence of Omicron on vaccine efficacy and durability: a neurology perspective [0.03%]
奥密克戎对疫苗效力和持久性的影响:神经学视角
Jethendra Kumar Muruganantham,Ramakrishnan Veerabathiran
Jethendra Kumar Muruganantham
Omicron variants present new challenges when it comes to understanding their impact on vaccines, antiviral strategies, and possible neurological consequences. This article describes the characteristics of the Omicron variant, its epidemiolo...
Urinary incontinence after COVID-19 vaccination: a case study in an 8-year-old boy [0.03%]
一例8岁男孩接种新冠疫苗后的尿失禁病例研究报告
Thi Loi Dao,Trung Kien Nguyen,Xuan Bai Nguyen et al.
Thi Loi Dao et al.
There have been many studies on the adverse effects of coronavirus disease 2019 (COVID-19) vaccines but the urinary incontinence after COVID-19 vaccination is rare. Here, we report an 8-year-old boy presented to outpatient department, Thai ...
Intranasal and intraperitoneal immunization against Brucella infection using niosome and mannosylated niosomes containing Brucella recombinant trigger factor/Bp26/Omp31 chimeric protein in a mouse model [0.03%]
负载布鲁氏菌重组TF-Bp26-Omp31嵌合蛋白的非离子胶束和甘露糖修饰非离子胶束经鼻和腹腔免疫小鼠的对比研究
Fahimeh Sharif,Razieh Nazari,Mahdi Fasihi-Ramandi et al.
Fahimeh Sharif et al.
Purpose: Brucellosis, a zoonotic infectious disease, is a worldwide health issue affecting animals and humans. No effective human vaccine and the complications caused by the use of animal vaccines are among the factors th...
Development and validation of enzyme-linked immunosorbent assay for anti-mouse pertussis immunoglobulin G using international reference anti- Bordetella pertussis mouse serum NIBSC 97/642 [0.03%]
应用国际标准血清NIBSC 97/642建立并验证了抗小鼠百日咳杆菌IgG ELISA检测方法
Kyu-Ri Kang,Yi-Hyeon Kwon,Gyu-Won Cho et al.
Kyu-Ri Kang et al.
Purpose: In this study, an in-house enzyme-linked immunosorbent assay (ELISA) was developed and validated. The titer of ELISA was calculated using the reference line (RFL) method based on the standard curve drawn using th...