Hyun Jung Lee,Sazaly Abu Bakar,Ok Sarah Shin
Hyun Jung Lee
Zika virus (ZIKV) infection as a cause of microcephaly and Guillain-Barré syndrome gained international attention during the 2015-2016 ZIKV epidemic in the Americas. However, over ten years later, there are still no approved ZIKV vaccines,...
Evaluation of oral and injectable liposome-based vaccines with synthesized lipid for Japanese encephalitis virus in Sprague-Dawley rats [0.03%]
评估合成脂质的口服和注射给药的日本脑炎病毒脂质体疫苗在Sprague-Dawley大鼠中的效果
Hani Lee,Young Min Woo,Keun Woo Lee et al.
Hani Lee et al.
Purpose: Japanese Encephalitis Virus (JEV) is a mosquito-borne flavivirus that causes severe neurological complications and high mortality rates in Asia. Developing vaccines is crucial for controlling its spread. Liposome...
Identification of conserved CD8+ T cell epitopes in Nipah virus towards vaccine development using an immunoinformatics approach [0.03%]
利用免疫信息学方法鉴定尼帕病毒中的保守CD8+t细胞表位以促进疫苗研发
Jeries Dylan T Yadao,Amizah Coleene B Alog,Leana Rich Herrera-Ong
Jeries Dylan T Yadao
Purpose: Developing a treatment for Nipah virus (NiV) infection is necessary due to its high fatality rate, broad host range, and unavailable licensed effective treatment. Therefore, this study aimed to identify candidate...
Nasal immunization with compound 48/80-adjuvanted acellular pertussis vaccines is an effective strategy to induce pertussis-specific systemic and mucosal immunity [0.03%]
卡介苗复合物48/80佐剂鼻内接种无细胞百日咳疫苗可有效诱导全身和粘膜免疫反应
Alison Hofmann Church,Soman N Abraham,Herman F Staats et al.
Alison Hofmann Church et al.
Purpose: Mast cell activating adjuvants induce vaccine-specific systemic and mucosal immunity when administered intranasally. Bordetella pertussis infects the respiratory tract and caused 0.45% childhood mortality in the ...
A promising Staphylococcus aureus vaccine adjuvant candidate to overcome Staphylococcal infection based on innate immunity [0.03%]
基于先天免疫克服金黄色葡萄球菌感染的疫苗佐剂候选药物的研究进展
Xinrui Mao,Thomas Söderhäll,Gi-Sub Choi et al.
Xinrui Mao et al.
Staphylococcus aureus-mediated human disease ranges from minor skin infection to life threatening diseases. In the past, infections caused by this bacterium could be treated with antibiotics. However, this species has become increasingly re...
Han Sol Lee,Ji Yun Noh,Hee Jin Cheong
Han Sol Lee
Influenza C virus (ICV) was discovered in 1947 and detected in humans, with natural infections occurring periodically. However, early studies on ICV were challenging in diagnosis because the virus is difficult to culture. As a result, the d...
The effect of COVID-19 vaccination on viral load among health care workers: a retrospective cohort study [0.03%]
COVID-19疫苗对医疗卫生人员病毒载量的影响：回顾性队列研究
Hajar Motamed,Shadi Siami,Zahra Abdan et al.
Hajar Motamed et al.
Purpose: The current novel coronavirus disease pandemic was declared by the World Health Organization in 2020. Considering the difference in the infection and mortality rates in healthcare workers in Iran compared to othe...
Guillain-Barré syndrome with T-cell receptor gene clonal rearrangement following COVID-19 vaccination: a case report [0.03%]
新型冠状病毒疫苗接种后出现T细胞受体基因重排的吉兰-巴雷综合征1例报告
Kensuke Matsumoto,Tatsuki Morioka,Katsuhiro Tokuda et al.
Kensuke Matsumoto et al.
The occurrence of Guillain-Barré syndrome (GBS) following coronavirus disease 2019 (COVID-19) vaccination have been documented; however, its pathogenesis remains unclear. We present a case of GBS associated with T-cell receptor (TCR) clona...
Assessment of naturally acquired IgG antibodies to pneumococcal vaccine serotypes in healthy and type 2 diabetic adults in India [0.03%]
评估印度健康成人和2型糖尿病成人中针对肺炎球菌疫苗血清型的自然获得性IgG抗体状况
Mettingal Ramakrishnan Shincy,Manheri Mavupadi Akhila,Govindan Vandana et al.
Mettingal Ramakrishnan Shincy et al.
Purpose: Streptococcus pneumoniae is a leading global cause of morbidity and mortality, particularly in individuals with type 2 diabetes, who are at increased risk due to altered immunity. Vaccination is crucial for preve...
Evaluation of the safety and immunogenicity of the ERAGS-GFP oral rabies vaccine in dogs [0.03%]
评估ERAGS-GFP口服狂犬病疫苗在狗身上的安全性和免疫原性
Dong-Kun Yang,Ju-Yeon Lee,Minuk Kim et al.
Dong-Kun Yang et al.
Rabies is a fatal zoonotic disease primarily transmitted through dog bites, making oral rabies vaccines critical for disease control. This study evaluated the immunogenicity of the ERAGS-GFP oral rabies vaccine strain in dogs. To optimize v...