Central precocious puberty with hypothalamic hamartoma: the first case reports of 2 siblings with different phenotypes of Seckel syndrome 5 [0.03%]
下丘脑错构瘤中枢性早熟：第1例Seckel综合征5型不同表型兄妹报告
Jisun Park,Minjun Jeon,Seri Maeng et al.
Jisun Park et al.
Hypothalamic hamartomas (HHs) are nonneoplastic mass lesions located in the hypothalamus that can cause central precocious puberty (CPP) and/or gelastic seizures. Seckel syndrome 5 (OMIM210600, SCKL5) is a rare autosomal recessive genetic s...
A novel compound variant in GNRHR causing congenital idiopathic hypogonadotropic hypogonadism in a young male Korean patient [0.03%]
GNRHR新复合变异导致的青春期内因性低促性腺素性性发育不良一例报告
Gimin Lee,Mi Seon Lee,Rosie Lee et al.
Gimin Lee et al.
Effectiveness of active video games in overweight and obese adolescents: a systematic review and meta-analysis of randomized controlled trials [0.03%]
超重和肥胖青少年积极视频游戏的有效性：随机对照试验的系统评价和meta分析
Zübeyde Ezgi Erçelik,Seda Çağlar
Zübeyde Ezgi Erçelik
Purpose: The purpose of this review was to assess the effect of active video games among overweight and obese adolescents. Methods: A s...
Clinical management and emerging therapies of FGFR3-related skeletal dysplasia in childhood [0.03%]
儿童FGFR3相关性骨骼发育不良的临床处理及新兴疗法
Hwa Young Kim,Jung Min Ko
Hwa Young Kim
Skeletal dysplasia is a diverse group of disorders that affect bone development and morphology. Currently, approximately 461 different genetic skeletal disorders have been identified, with over 430 causative genes. Among these, fibroblast g...
Classic and backdoor pathways of androgen biosynthesis in human sexual development [0.03%]
人类性发育中雄激素生物合成的经典途径和旁路途径
Hyun Gyung Lee,Chan Jong Kim
Hyun Gyung Lee
Both genes and hormones regulate human sexual development. Although ovarian hormones are not essential for female external genitalia development, male sexual development requires the action of testicular testosterone and dihydrotestosterone...
Cardiometabolic risk factors and metabolic syndrome based on severity of obesity in Korean children and adolescents: data from the Korea National Health and Nutrition Examination Survey 2007-2018 [0.03%]
基于肥胖严重程度的韩国儿童和青少年心血管代谢危险因素及代谢综合征：2007-2018年韩国国民健康和营养 examination 数据分析
Minseung Kim,Jaehyun Kim
Minseung Kim
Purpose: Data regarding cardiometabolic risk factors (CMRFs) and metabolic syndrome (MetS) by body mass index (BMI) category in Korean youth are sparse. M...
Combination therapy of liothyronine and levothyroxine for hypothyroidism-induced dilated cardiomyopathy [0.03%]
左旋甲状腺素与三碘甲状腺原氨酸联合治疗甲减所致扩张型心肌病
Youngha Choi,Se Yong Jung,Jung Min Park et al.
Youngha Choi et al.
Thyroid hormone plays a vital role in regulating human metabolism. They affect the functions of major organs, such as the brain, liver, skeletal muscle, and heart. Hypothyroidism can lead to dilated cardiomyopathy and decreased heart functi...
Pathological brain lesions in girls with central precocious puberty at initial diagnosis in Southern Vietnam [0.03%]
越南南部中枢性早熟女童初诊时脑靶器官病变情况病理分析
Quynh Thi Vu Huynh,Ban Tran Ho,Nguyen Quoc Khanh Le et al.
Quynh Thi Vu Huynh et al.
Purpose: Cranial magnetic resonance imaging (MRI) is recommended to identify intracranial lesions in girls with central precocious puberty (CPP). Yet, the use of routine MRI scans in girls with CPP is still debatable, as ...