Multiple Drug Regimen-Refractory Rosai-Dorfman-Destombes Disease Mimicking Relapsing Polychondritis Successfully Treated with Cobimetinib [0.03%]
美罗华联合来那度胺治疗复发难治性Rosai-Dorfman-Destombes病合并类白塞病型血管炎及成人Still病要素病例报告及其对CRA通路活化的研究：一项罕见病病例报道
Kima López-Aldabe,Francesc Escrihuela-Vidal,Manel Tuells-Morales et al.
Kima López-Aldabe et al.
Rosai-Dorfman-Destombes disease (RDD) or sinus histiocytosis with massive lymphadenopathy is a rare non-Langerhans cell histiocytosis of unknown cause. The disease often manifests as painless bilateral cervical lymphadenopathy associated wi...
The Management of Acute Onset Complete Heart Block and Atrial Flutter in a Patient with COVID-19 [0.03%]
COVID-19患者完全性房室传导阻滞和房性心动过速的治疗
Murtaza Hussain,Dominic Awuah,Smit Deliwala et al.
Murtaza Hussain et al.
Coronavirus disease (COVID-19) has infected millions of people worldwide. Its cardiac presentations include myocarditis, arrhythmias and structural heart changes even in young and healthy individuals. The long-term sequelae of these manifes...
Type II Abernethy Malformation: A Rare Cause of Hepatic Encephalopathy in Adulthood [0.03%]
成人肝性脑病的罕见病因Ⅱ型阿伯内西畸形
Inês Gonçalves,Daniela Barros,Margarida Araújo et al.
Inês Gonçalves et al.
Abernethy malformation is a rare congenital extrahepatic portosystemic shunt with variable clinical manifestations, mainly associated with the portosystemic shunt. Hepatic encephalopathy can be the first manifestation. We present the case o...
Wilson's Disease: First Report of Two Combined Mutational Variants in a Portuguese Patient [0.03%]
威尔逊病合并两种突变型的葡萄牙患者首例报告
Miguel Trindade,Joana Carvalho,Mariana Barosa et al.
Miguel Trindade et al.
Wilson's disease is a rare autosomal recessive condition. A defect on the copper carrier protein ATP7B prevents the excretion of copper, which then accumulates in several organs. The prognosis of Wilson's disease is favourable if the diagno...
Dysphagia as a Rare Presentation of Cervical Cancer with Mediastinal Metastasis [0.03%]
咽部异物感作为颈椎癌伴纵隔转移的罕见表现形式
Vinit Singh,Dhairya Gor,Sarah Azad et al.
Vinit Singh et al.
Dysphagia has a broad aetiology and so it is essential to identify the precise cause. Cervical cancer metastasis is distinctive in that it usually involves local lymph node invasion; however, approximately 1% of cases have mediastinal invol...
Micah LA Heldeweg,Joris R Drossaers,Kenrick Berend
Micah LA Heldeweg
Hyperglycaemic hyperosmolar state (HHS) and diabetic ketoacidosis (DKA) features can occur simultaneously in 27% of diabetic emergencies and have a two-fold increased risk of death. Despite the high prevalence of this combination, recommend...
Mariana Bilreiro,Luís Marote Correia
Mariana Bilreiro
Introduction: Tetanus is a vaccine-preventable disease caused by a neurotoxin produced by Clostridium tetani that proliferates in wound sites. Toxin interference with neuromuscular function leads to spasms. Trismus, risus...
Alkaline Diuresis as Treatment for 2,4-D Dimethylamine Herbicide Intoxication [0.03%]
碱性利尿法治疗2,4-二氯苯氧乙酸丁氧基丙胺中毒
Apolonia Berenika Badu,Ade Ajeng Cempakadewi,Brigitta Marcia Budihardja et al.
Apolonia Berenika Badu et al.
Acute intoxication with 2,4-D dimethylamine is rare, often fatal and can cause signs and symptoms in different organ systems. This case report describes the effectiveness of alkaline diuresis as a life-saving treatment for chlorophenoxy int...
Yaiza Altuzarra-Ranedo,Daniel Gómez-Ramírez,María Rodríguez-Laguna et al.
Yaiza Altuzarra-Ranedo et al.
We present the case of a 59-year-old man with acute B19 parvovirus infection who developed a systemic inflammatory reaction similar to adult-onset Still's disease (AOSD). We discuss the clinical challenge due to overlapping symptoms to dist...
Márcia Agostinho Pereira,Madalena Monjardino Lobão,António Mesquita et al.
Márcia Agostinho Pereira et al.
We present the case of a 53-year-old woman of Portuguese ancestry with a diagnosis of progressive systemic sclerosis (SSc), proposed for haematopoietic stem cell transplantation (HSCT). Clinical re-evaluation when assessing eligibility for ...