Andrei G Vlassenko,Marcus E Raichle
Andrei G Vlassenko
Genetic, biochemical, pathological, and biomarker data demonstrate that Alzheimer's disease (AD) pathology, including the initiation and progressive buildup of insoluble forms of beta-amyloid (Aβ), appears to begin ~ 10-15 years prior to t...
Mario Quarantelli
Mario Quarantelli
Neuroinflammation encompasses a wide range of humoral and cellular responses, not only enabling the CNS to fight various noxious events, including infections and trauma, but also playing a critical role in autoimmune as well as in neurodege...
Cardiac sympathetic activity in hypertrophic cardiomyopathy and Tako-tsubo cardiomyopathy [0.03%]
肥厚性心肌病和 tako-tsubo 心肌病的 cardiac sympathetic 活动
Derk O Verschure,Berthe L F van Eck-Smit,G Aernout Somsen et al.
Derk O Verschure et al.
123I-meta-iodobenzylguanidine (123I-mIBG) scintigraphy has been established as an important technique to evaluate cardiac sympathetic function and it has been shown to be of clinical value, especially for the assessment of prognosis, in man...
PET imaging of the autonomic myocardial function: methods and interpretation [0.03%]
心肌自主神经功能的正电子发射断层扫描显像：方法与解读
Walter Noordzij,Riemer H J A Slart
Walter Noordzij
Cardiac positron emission tomography (PET) is mainly applied in myocardial perfusion and viability detection. Noninvasive imaging of myocardial innervation using PET is a valuable additional methodology in cardiac imaging. Novel methods and...
Piotr Slomka,Daniel S Berman,Erick Alexanderson et al.
Piotr Slomka et al.
Positron Emission Tomography (PET) has several clinical and research applications in cardiovascular imaging. Myocardial perfusion imaging with PET allows accurate global and regional measurements of myocardial perfusion, myocardial blood fl...
Imaging Amyloidopathy in Parkinson Disease and Parkinsonian Dementia Syndromes [0.03%]
帕金森病和帕金森综合征痴呆的淀粉样病变影像学研究
Kirk A Frey,Myria Petrou
Kirk A Frey
Dementia arising in patients with Parkinson disease or parkinsonian neurodegeneration comprises a heterogeneous neuropathology. Clinical labeling of patients with both dementia and Parkinson disease is dichotomous, depending on the temporal...
Ana M Catafau,Santiago Bullich
Ana M Catafau
As a biomarker of beta-amyloid, positron emission tomography (PET) amyloid imaging offers a unique opportunity to detect the presence of this protein in the human body during life. Besides Alzheimer's disease (AD), deposits of beta-amyloid ...
Osama Sabri,John Seibyl,Christopher Rowe et al.
Osama Sabri et al.
Florbetaben is a fluorine-18 (18F)-labeled stilbene derivative that was developed as a positron emission tomography (PET) tracer for routine clinical application to visualize β-amyloid plaques in the Alzheimer's disease (AD) brain. The tra...
Opportunities for NanoTheranosis in Lung Cancer and Pulmonary Metastasis [0.03%]
纳米诊疗技术在肺癌及肺转移癌中的应用机遇
J Key,Y-S Kim,F Tatulli et al.
J Key et al.
Malignancies of the lungs, both primary and metastatic, are the leading cause of death worldwide. Over 1.5 million new cases of primary lung cancer are diagnosed annually worldwide with a dismal five-year survival rate of approximately 15%,...
Jocelyn Dupuis,François Harel,Quang T Nguyen
Jocelyn Dupuis
The pulmonary circulation, at the unique crossroads between the left and the right heart, is submitted to large physiologic hemodynamic variations and possesses numerous important metabolic functions mediated through its vast endothelial su...