Upfront Combined Hydroxyurea and Imatinib versus Imatinib Monotherapy in Newly Diagnosed Chronic Phase Chronic Myeloid Leukemia: A Randomized Controlled Trial [0.03%]
羟基脲联合伊马替尼与单用伊马替尼治疗新诊断慢性期慢性粒细胞白血病的随机对照试验
Rituparna Chetia,Sarika Palepu,Vikramjeet Dutta et al.
Rituparna Chetia et al.
Background: Tyrosine kinase inhibitors like imatinib have become the cornerstone of therapy in chronic phase-chronic myeloid leukemia (CML-CP). However, the role of hydroxyurea (HU), a deoxyribonucleic acid synthesis inhi...
Clinical Outcomes of Patients with Multiple Myeloma Presenting with Renal Failure [0.03%]
多发性骨髓瘤肾功能衰竭患者的临床结果分析
Joydeep Singh Vasant,Naveen Gupta,Hemant Malhotra et al.
Joydeep Singh Vasant et al.
Aims and objective: This article studies the clinical outcome of patients with multiple myeloma who have renal failure at presentation. Methodology: ...
Analysis of Treatment Outcome in Large Granular Lymphocytic Leukemia: A Retrospective Study from India [0.03%]
印度大颗粒淋巴细胞白血病治疗效果分析:一项回顾性研究
Mir Sadaqat Hassan Zafar,Sajad Ahmad Geelani,Javid Rasool Bhat
Mir Sadaqat Hassan Zafar
Large granular lymphocytic (LGL) leukemia is a rare and indolent lymphoproliferative disorder that belongs to mature T and natural killer (NK) cell neoplasms, as per the World Health Organization classification. This article assesses the re...
FLAG with Bortezomib Salvage Therapy in Relapsed/Refractory Childhood Leukemia-A Reliable Bridge to Transplantation with Limited Toxicity [0.03%]
FLAG联合硼替佐米解救治疗复发/难治儿童急性白血病诱导缓解并顺利移植的安全性分析
Sreedhar Jayakrishnan Cherulil,Kesavan Melarcode Ramanan,K V Gangadharan et al.
Sreedhar Jayakrishnan Cherulil et al.
Relapsed refractory leukemia represents a difficult-to-treat population of patients. The balance between perceived benefit and potential side effects along with the significant financial burden of managing multidrug-resistant sepsis are fac...
A Prospective Randomized Controlled Trial to Study the Role of Sulfasalazine in the Prevention of Acute Gastrointestinal Toxicities in Patients of Carcinoma of the Cervix Receiving Concurrent Chemoradiation [0.03%]
硫酸羟氨嘧啶预防宫颈癌根治性同步放化疗急性胃肠毒性作用的前瞻性随机对照研究
Vasireddy Abhinav,Naga Chandra Sekhar Darisi,Amrutha Iyyapu et al.
Vasireddy Abhinav et al.
The present study aimed to evaluate the effectiveness of sulfasalazine in preventing acute gastrointestinal (GI) toxicities in patients with cervical carcinoma receiving concurrent chemoradiation. This prospective randomized controlled stud...
Primary Breast Lymphoma: A Rare but Important Differential Diagnosis in Patients with Breast Malignancy [0.03%]
原发性乳腺淋巴瘤:乳腺恶性肿瘤少见但重要的鉴别诊断
Irappa Madabhavi,Malay Sarkar,Raghavendra Sagar et al.
Irappa Madabhavi et al.
This report is based upon the case of a young lady who presented with a history of a breast lump, which despite clinically resembling a carcinoma, was subsequently diagnosed to be a primary breast lymphoma (PBL). Though rare in incidence, P...
Prevalence and Pattern of Nodal Metastases in Ovarian Malignancy: A Perioperative Audit [0.03%]
卵巢恶性肿瘤淋巴结转移的分布及模式:一项围手术期审计研究
Ashok Padhy,Sony Nanda,Bhagyalaxmi Nayak
Ashok Padhy
It is still unclear whether or not full nodal dissection and detailed staging offer any benefits. Little is known regarding the degree of nodal involvement based on histotype. We aimed to assess the lymphatic dissemination patterns and prev...
Intensive Oral Hygiene Interventions during Therapy of Acute Leukemia May Result in Detrimental Outcomes: A Randomized Clinical Trial [0.03%]
急性白血病治疗期间的强化口腔卫生干预可能产生不利后果:一项随机临床试验
Biswajit Dubashi,Nirmal Pratap Mote,B Krishnan et al.
Biswajit Dubashi et al.
Objectives: There are no standard guidelines on oro-dental care during induction therapy of acute leukemia (AL). This study aimed to assess the effect of intensive oral hygiene practice on oral mucositis, infection, and d...
FLAG with Bortezomib in Children and Adolescents with Relapsed/Refractory Acute Myeloid Leukemia in a Resource-Limited Setting: A Single-Center Experience from India [0.03%]
硼替佐米联合化疗治疗印度儿科急性髓系细胞白血病复发或难治患者:一项单中心研究
Dipesh Dave,Himangi Tak,Maharshi Trivedi et al.
Dipesh Dave et al.
Objectives: The present study aimed to evaluate the impact, challenges, and outcome by adding bortezomib to the FLAG (fludarabine, cytarabine, and filgrastim) regimen in these populations in a resource-constraint setting....
Spectrum of Surgico-Pathological Factors and Lymph Node Metastasis among Epithelial Ovarian Cancers: Experience of a Single Tertiary Care Institution from India [0.03%]
单中心来自印度的上皮性卵巢癌的手术病理因素和淋巴结转移特征分析:一项回顾性研究
Anupama Bahadur,Pallavi Verma,Shalini Rajaram et al.
Anupama Bahadur et al.
Introduction Epithelial ovarian cancer (EOC) is one of the leading causes of mortality among women worldwide. The present study aimed to estimate the frequency of various histopathological types, clinical and surgico-pathological factors, a...