Mechanistic insights into the oncolytic activity of vesicular stomatitis virus in cancer immunotherapy [0.03%]
关于-vesicular- stomatitis-病毒在癌症免疫治疗中的溶瘤活性的机制研究
Boris Simovic,Scott R Walsh,Yonghong Wan
Boris Simovic
Immunotherapy and oncolytic virotherapy have both shown anticancer efficacy in the clinic as monotherapies but the greatest promise lies in therapies that combine these approaches. Vesicular stomatitis virus is a prominent oncolytic virus w...
Patient-derived mesenchymal stem cells as delivery vehicles for oncolytic virotherapy: novel state-of-the-art technology [0.03%]
基于患者来源的间充质干细胞作为溶瘤病毒治疗的递送载体：新颖且前沿的技术
Manuel Ramírez,Javier García-Castro,Gustavo J Melen et al.
Manuel Ramírez et al.
Oncolytic virotherapy is gaining interest in the clinic as a new weapon against cancer. In vivo administration of oncolytic viruses showed important limitations that decrease their effectiveness very significantly: the antiviral immune resp...
Oncolytic Sendai virus-based virotherapy for cancer: recent advances [0.03%]
基于条件复制塞奈病毒的癌症溶瘤病毒治疗：最近的研究进展
Kotaro Saga,Yasufumi Kaneda
Kotaro Saga
Many drugs have been developed and optimized for the treatment of cancer; however, it is difficult to completely cure cancer with anticancer drugs alone. Therefore, the development of new therapeutic technologies, in addition to new antican...
Oncolytic virotherapy for human malignant mesothelioma: recent advances [0.03%]
人类恶性间皮瘤的溶瘤病毒治疗：最近的研究进展
Nicolas Boisgerault,Carole Achard,Tiphaine Delaunay et al.
Nicolas Boisgerault et al.
Cancer virotherapy is an attractive alternative to conventional treatments because it offers a wide range of antitumor effects due to 1) the diversity of the oncolytic viruses that are now available and 2) their multifaceted activities agai...
Brian Hutzen,Corey Raffel,Adam W Studebaker
Brian Hutzen
A successful oncolytic virus is one that selectively propagates and destroys cancerous tissue without causing excessive damage to the normal surrounding tissue. Oncolytic measles virus (MV) is one such virus that exhibits this characteristi...
On the potential of oncolytic virotherapy for the treatment of canine cancers [0.03%]
溶瘤病毒疗法治疗犬科动物癌症的潜力探讨
Amy L MacNeill
Amy L MacNeill
Over 6 million dogs are diagnosed with cancer in the USA each year. Treatment options for many of these patients are limited. It is important that the veterinary and scientific communities begin to explore novel treatment protocols for dogs...
Oncolytic virotherapy for head and neck cancer: current research and future developments [0.03%]
溶瘤病毒疗法用于头颈癌：当前研究和未来前景
Akshiv Malhotra,Arun Sendilnathan,Matthew O Old et al.
Akshiv Malhotra et al.
Head and neck cancer (HNC) is the sixth most common malignancy worldwide. Despite recent advancements in surgical, chemotherapy, and radiation treatments, HNC remains a highly morbid and fatal disease. Unlike many other cancers, local contr...
Novel therapeutic strategies in human malignancy: combining immunotherapy and oncolytic virotherapy [0.03%]
人类恶性肿瘤的新型治疗策略：免疫疗法与溶瘤病毒疗法相结合
Padma Sampath,Steve H Thorne
Padma Sampath
Results from randomized clinical trials over the last several years have finally begun to demonstrate the potential of oncolytic viral therapies to treat a variety of cancers. One reason for these successes has been the realization that thi...
James J Cody,Douglas R Hurst
James J Cody
New therapies for metastatic breast cancer patients are urgently needed. The long-term survival rates remain unacceptably low for patients with recurrent disease or disseminated metastases. In addition, existing therapies often cause a vari...
Therapeutic potential of oncolytic Newcastle disease virus: a critical review [0.03%]
新城疾病病毒癌症治疗潜力的批判性综述
Shay Tayeb,Zichria Zakay-Rones,Amos Panet
Shay Tayeb
Newcastle disease virus (NDV) features a natural preference for replication in many tumor cells compared with normal cells. The observed antitumor effect of NDV appears to be a result of both selective killing of tumor cells and induction o...